PJ Vogt

Okay, so here's something.

Our show's motto, no question too big, no question too small, but there's some questions that I have on this show avoided.

I'll give you an example, GLP-1s.

Surge Engine has barely acknowledged their existence, which is fine, except I read a lot about them, I think a lot about them, and in my private life, I talk a lot about them.

But when they cannonballed into American culture, I had a lot of questions that I didn't want to ask in public.

In 2022 and 2023, GLP-1s were just, for me, too hot a topic.

Going online felt like walking into a crazy shootout at an old Western saloon, except instead of gunslingers, it was all fast draw scolders.

There were scolders out there scolding celebrities for taking GLP-1s, but then they were getting scolded by other scolders for scolding celebrities.

Some people got scolded because they were taking the drugs despite not being fat enough, scolded for wanting to lose 15 pounds.

Rich people, of course, were getting scolded all over the place, accused of ripping GLP-1s out of the hands of the people who actually needed them.

It was scolding mayhem.

Meanwhile, offline, in real life, 20% of the people I knew just lost 15 to 40 pounds.

They seemed happy, and I had questions.

What did we really know about these drugs?

Were they helping people the way they claimed to?

What were the side effects?

I had questions, but I hate getting scolded, so I kept my mouth shut.

Meanwhile, in 2026, the scolders have moved on to other topics, topics I'll cover in 2029.

But today, we can finally get some answers on these fascinating drugs, which it turns out are much weirder than we ever knew.

So this week, we're going to talk to a doctor who's going to tell us the story of GLP-1s from her perspective, which is a very unique one, because she's a doctor to a particular patient population that we don't hear from much in the media, almost never, and who were very absent from the entire early discourse around these drugs.