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All-In with Chamath, Jason, Sacks & Friedberg

In conversation with Sam Altman

Fri, 10 May 2024

Description

(0:00) Welcoming Sam Altman to the show! (2:28) What's next for OpenAI: GPT-5, open-source, reasoning, what an AI-powered iPhone competitor could look like, and more (21:56) How advanced agents will change the way we interface with apps (33:01) Fair use, creator rights, why OpenAI has stayed away from the music industry (42:02) AI regulation, UBI in a post-AI world (52:23) Sam breaks down how he was fired and re-hired, why he has no equity, dealmaking on behalf of OpenAI, and how he organizes the company (1:05:33) Post-interview recap (1:10:38) All-In Summit announcements, college protests (1:19:06) Signs of innovation dying at Apple: iPad ad, Buffett sells 100M+ shares, what's next? (1:29:41) Google unveils AlphaFold 3.0 Follow Sam: https://twitter.com/sama Follow the besties: https://twitter.com/chamath https://twitter.com/Jason https://twitter.com/DavidSacks https://twitter.com/friedberg Follow on X: https://twitter.com/theallinpod Follow on Instagram: https://www.instagram.com/theallinpod Follow on TikTok: https://www.tiktok.com/@all_in_tok Follow on LinkedIn: https://www.linkedin.com/company/allinpod Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect Referenced in the show: https://twitter.com/EconomyApp/status/1622029832099082241 https://sacra.com/c/openai https://twitter.com/tim_cook/status/1787864325258162239 https://openai.com/index/introducing-the-model-spec https://twitter.com/SabriSun_Miller/status/1788298123434938738 https://www.archives.gov/founding-docs/bill-of-rights-transcript https://twitter.com/ClayTravis/status/1788312545754825091 https://www.inc.com/bill-murphy-jr/warren-buffett-just-sold-more-than-100-million-shares-of-apple-reason-why-is-eye-opening.html https://www.youtube.com/watch?v=snbTCWL6rxo https://www.digitimes.com/news/a20240506PD216/apple-ev-startup-genai.html https://www.theonion.com/fuck-everything-were-doing-five-blades-1819584036 https://blog.google/technology/ai/google-deepmind-isomorphic-alphafold-3-ai-model

Audio
Transcription

0.269 - 19.526 Jason Calacanis

I first met our next guest, Sam Altman, almost 20 years ago when he was working on a local mobile app called Looped. We were both backed by Sequoia Capital. And in fact, we were both in the first class of Sequoia Scouts. He did investment in a little unknown fintech company called Stripe. I did Uber. And in that tiny experimental fund- You did Uber?

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19.566 - 23.73 Sam Altman

I've never heard that before. Yeah, I think so. It's possible. You've got it starting already.

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24.67 - 26.592 Chamath Palihapitiya

You should write a book, Jacob. Maybe.

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26.672 - 26.972 Sam Altman

Maybe.

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31.886 - 33.108 David Sacks

Rain Man, David Sack.

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33.368 - 41.881 David Friedberg

And it said, we open sourced it to the fans and they've just gone crazy with it. Love you guys. Queen of Kinwa.

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45.017 - 61.131 Jason Calacanis

That tiny experimental fund that Sam and I were part of as scouts is Sequoia's highest multiple returning fund. A couple of low-digit millions turned into over 200 million, I'm told. Really? Yeah, that's what I was told by Ruloff, yeah. And he did a stint at Y Combinator, where he was president from 2014 to 2019.

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61.431 - 89.413 Jason Calacanis

In 2016, he co-founded OpenAI with the goal of ensuring that artificial general intelligence benefits all of humanity. In 2019, he left YC to join OpenAI full-time as CEO. Things got really interesting on November 30th of 2022. That's the day OpenAI launched ChatGPT. In January 2023, Microsoft invested $10 billion. In November 2023, Over a crazy five-day span, Sam was fired from OpenAI.

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90.054 - 111.672 Jason Calacanis

Everybody was going to go work at Microsoft. A bunch of heart emojis went viral on X slash Twitter, and people started speculating that the team had reached artificial general intelligence. The world was going to end, and suddenly... A couple days later, he was back to being the CEO of OpenAI. In February, Sam was reportedly looking to raise $7 trillion for an AI chip project.

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112.253 - 128.977 Jason Calacanis

This after it was reported that Sam was looking to raise a billion from Masayoshi-san to create an iPhone killer with Johnny Ive, the co-creator of the iPhone. All of this while chat GPT has become better and better and a household name. It's having a massive impact on how we work and how work is getting done.

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129.377 - 144.541 Jason Calacanis

And it's reportedly the fastest product to hit 100 million users in history in just two months. And check out OpenAI's insane revenue ramp up. They reportedly hit 2 billion in ARR last year. Welcome to the All In podcast, Sam Altman.

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145.001 - 146.342 David Sacks

Thank you. Thank you, guys.

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146.642 - 147.562 Jason Calacanis

Sax, you want to lead us off here?

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148.022 - 164.494 David Sacks

Okay, sure. I mean, I think the whole industry is waiting with bated breath for the release of GPT-5. I guess it's been reported that it's launching sometime this summer, but that's a pretty big window. Can you narrow that down? I guess, where are you in the release of GPT-5?

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164.554 - 167.937 Sam Altman

We take our time on releases of major games.

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168.627 - 193.276 Sam Altman

New models, and I don't think we I think it will be great When we do it, and I think we'll be thoughtful about how we do it Like we may release it in a different way than we've released previous models Also, I don't even know if we'll call it GPT-5 What I what I will say is you know a lot of people have noticed how much better GPT-4 has gotten Since we've released it and particularly over the last few months.

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194.016 - 221.376 Sam Altman

I think I I think that's a better hint of what the world looks like, where it's not the one, two, three, four, five, six, seven, but you use an AI system and the whole system just gets better and better fairly continuously. I think that's both a better technological direction, I think that's easier for society to adapt to. But I assume that's where we'll head.

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221.596 - 234.801 David Friedberg

Does that mean that there's not going to be long training cycles and it's continuously retraining or training submodels, Sam? And maybe you could just speak to us about what might change architecturally going forward with respect to large models.

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235.962 - 244.365 Sam Altman

Well, I mean, one thing that you could imagine is just that you keep training a model. That would seem like a reasonable thing to me.

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246.457 - 267.533 Jason Calacanis

And we talked about releasing it differently this time. Are you thinking maybe releasing it to the paid users first or a slower rollout to get the red teams tight since now there's so much at stake? You have so many customers actually paying and you've got everybody watching everything you do. You have to be more thoughtful now, yeah?

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267.553 - 279.937 Sam Altman

GPT-4 is still only available to the paid users, but one of the things that we really want to do is figure out how to make more advanced technology available to free users too. I think that's a super important part of our mission.

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280.197 - 301.705 Sam Altman

And this idea that we build AI tools and make them super widely available, free or not that expensive, whatever it is, so that people can use them to go kind of invent the future rather than the magic AGI in the sky inventing the future and showing it down upon us. That seems like a much better path. It seems like a more inspiring path. I also think it's where things are actually heading.

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303.8 - 309.865 Sam Altman

It makes me sad that we have not figured out how to make GPT-4 level technology available to free users. It's something we really want to do.

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310.546 - 311.807 Jason Calacanis

It's just very expensive, I take it.

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311.847 - 312.568 Sam Altman

It's very expensive.

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312.948 - 315.11 Jason Calacanis

Yeah. Chamath, your thoughts?

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315.45 - 341.947 Chamath Palihapitiya

I think maybe the two big vectors, Sam, that people always talk about is that underlying cost and sort of the latency that's kind of rate-limited a killer app, and then I think the second is sort of the long-term ability for people to build in an open source world versus a closed source world. And I think the crazy thing about this space is that the open source community is rabid.

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341.987 - 363.857 Chamath Palihapitiya

So one example that I think is incredible is, you know, we had these guys do a pretty crazy demo for Devon, remember, like even like five or six weeks ago that looked incredible. And then some kid just published it under an open MIT license, like OpenDevon. And it's incredibly good and almost as good as that other thing that was closed source.

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364.717 - 374.48 Chamath Palihapitiya

So maybe we can just start with that, which is tell me about the business decision to keep these models closed source. And where do you see things going in the next couple of years?

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375.754 - 398.383 Sam Altman

So on the first part of your question, speed and cost, those are hugely important to us. And I don't want to give a timeline on when we can bring them down a lot because research is hard, but I am confident we'll be able to. We want to cut the latency super dramatically. We want to cut the cost really, really dramatically. And I believe that will happen.

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398.423 - 424.951 Sam Altman

We're still so early in the development of the science and understanding how this works. Plus, we have all the engineering tailwinds. So I don't know when we get to intelligence too cheap to meter and so fast that it feels instantaneous to us and everything else, but... I do believe we can get there for a pretty high level of intelligence. It's important to us.

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425.251 - 446.544 Sam Altman

It's clearly important to users, and it'll unlock a lot of stuff. On the sort of open source, closed source thing, I think there's great roles for both, I think. You know, we've open sourced some stuff. We'll open source more stuff in the future. But really, like, our mission is to build towards AGI and to figure out how to broadly distribute its benefits. We have a strategy for that.

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446.564 - 464.696 Sam Altman

It seems to be resonating with a lot of people. It obviously isn't for everyone, and there's, like, a big ecosystem, and there will also be open source models and people who build that way. One area that I'm particularly interested personally in open source for is I want an open source model that is as good as it can be that runs on my phone.

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465.749 - 475.573 Sam Altman

And that, I think, is going to, you know, the world doesn't quite have the technology for a good version of that yet. But that seems like a really important thing to go do at some point.

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475.613 - 476.734 Jason Calacanis

Will you do? Will you do that?

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476.834 - 478.654 Sam Altman

I don't know if we will or someone will.

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478.674 - 490.414 David Sacks

What about Lama 3? Llama 3 running on a phone? Well, I guess maybe there's like a $7 billion version. Yeah, yeah. I don't know if that will fit on a phone or not.

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490.915 - 496.82 Sam Altman

That should be fittable on a phone, but I'm not sure if that one is like... I haven't played with it.

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496.84 - 516.361 David Sacks

I don't know if it's good enough to kind of do the thing I'm thinking about here. So when Llama 3 got released, I think the big takeaway for a lot of people was, oh, wow, they've like caught up to GPT-4. I don't think it's equal in all dimensions, but it's like pretty... pretty close or pretty in the ballpark. I guess the question is, you know, you guys released four a while ago.

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516.541 - 529.728 David Sacks

You're working on five or, you know, more upgrades to four. I mean, I think to Jamal's point about Devin, how do you stay ahead of open source? I mean, that's just like a very hard thing to do in general, right? I mean, how do you think about that?

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531.489 - 554.375 Sam Altman

What we're trying to do is not make the sort of smartest decisions set of weights that we can. But what we're trying to make is like this useful intelligence layer for people to use. And a model is part of that. I think we will stay pretty far ahead of, I hope we'll stay pretty far ahead of the rest of the world on that. But

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555.492 - 571.922 Sam Altman

There's a lot of other work around the whole system that's not just that the model waits. And we'll have to build up enduring value the old-fashioned way like any other business does. We'll have to figure out a great product and reasons to stick with it and deliver it at a great price.

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572.264 - 593.18 Jason Calacanis

When you founded the organization, the stated goal or part of what you discussed was, hey, this is too important for any one company to own it. So therefore, it needs to be open. Then there was the switch. Hey, it's too dangerous for anybody to be able to see it. And we need to lock this down because you had some fear about that, I think. Is that accurate?

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593.2 - 611.788 Jason Calacanis

Because the cynical side is like, well, this is a capitalistic move. And then the, I think, You know, I'm curious what the decision was here in terms of going from open. The world needs to see this. It's really important to close. Only we can see it. Well, how did you come to that conclusion?

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612.108 - 633.327 Sam Altman

Part of the reason that we released ChatGPT was we want the world to see this. And we've been trying to tell people that AI is really important. And if you go back to like October of 2022, not that many people thought AI was going to be that important or that it was really happening. No. And a huge part of what we try to do is put the technology in the hands of people.

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633.967 - 651.641 Sam Altman

Now, again, there's different ways to do that. And I think there really is an important role to just say, like, here's the way to have at it. But the fact that we have so many people using a free version of ChatGPT that we don't run ads on, we don't try to make money on, we just put out there because we want people to have these tools, I think has done a lot to...

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652.742 - 668.889 Sam Altman

provide a lot of value and teach people how to fish, but also to get the world really thoughtful about what's happening here. Now, we still don't have all the answers, and we're fumbling our way through this like everybody else, and I assume we'll change strategy many more times as we learn new things.

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669.429 - 687.674 Sam Altman

You know, when we started OpenAI, we had really no idea about how things were going to go, that we'd make a language model, that we'd ever make a product. We started off just... I remember very clearly that first day where we're like, well, Now we're all here. That was, you know, it was difficult to get this set up, but what happens now? Maybe we should write some papers.

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687.734 - 698.466 Sam Altman

Maybe we should stand around a whiteboard. And we've just been trying to like put one foot in front of the other and figure out what's next and what's next and what's next. And... I think we'll keep doing that.

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698.886 - 719.1 Chamath Palihapitiya

Can I just replay something and just make sure I heard it right? I think what you were saying on the open source, closed source thing is, if I heard it right, all these models, independent of the business decision you make, are going to become asymptotically accurate towards some amount of accuracy. Not all, but let's just say there's four or five that are

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720.851 - 742.357 Chamath Palihapitiya

well-capitalized enough, you guys, Meta, Google, Microsoft, whomever, right? So let's just say four or five, maybe one startup. And on the open web. And then quickly... the accuracy or the value of these models will probably shift to these proprietary sources of training data that you could get that others can't or others can get that you can't.

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742.537 - 751.5 Chamath Palihapitiya

Is that how you see this thing evolving, where the open web gets everybody to a certain threshold and then it's just an arms race for data beyond that?

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752.583 - 773.5 Sam Altman

So I definitely don't think it'll be an arms race for data, because when the models get smart enough at some point, it shouldn't be about more data, at least not for training. It may matter data to make it useful. Look, the one thing that I have learned most throughout all of this is that it's hard to make confident statements a couple of years in the future about where this is all going to go.

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774.02 - 797.442 Sam Altman

And so I don't want to try now. I will say that I expect lots of very capable models in the world. And, you know, like, it feels to me like we just, like, stumbled on a new fact of nature or science or whatever you want to call it, which is, like, we can create, you can, like... I mean, I don't believe this literally, but it's like a spiritual point.

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797.462 - 814.49 Sam Altman

You know, intelligence is just this emergent property of matter, and that's like a rule of physics or something. So people are going to figure that out. But there will be all these different ways to design the systems. People will make different choices, figure out new ideas. And I'm sure, like, you know,

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817.199 - 827.685 Sam Altman

Like any other industry, I would expect there to be multiple approaches and different people like different ones. Some people like iPhones, some people like an Android phone. I think there will be some effect like that.

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828.005 - 847.381 Chamath Palihapitiya

Let's go back to that first section of just the cost and the speed. all of you guys are sort of a little bit rate limited on literally Nvidia's throughput, right? And I think that you and most everybody else have sort of effectively announced how much capacity you can get just because it's as much as they can spin out.

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848.302 - 860.965 Chamath Palihapitiya

What needs to happen at the substrate so that you can actually compute cheaper, compute faster, get access to more energy? How are you helping to frame out the industry solving those problems?

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861.665 - 888.641 Sam Altman

We'll make huge algorithmic gains for sure, and I don't want to discount that. I'm very interested in chips and energy, but if we can make a same quality model twice as efficient, that's like we had twice as much compute. And I think there's a gigantic amount of work to be done there. And I hope we'll start really seeing those results. Other than that, the whole supply chain is very complicated.

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888.661 - 910.248 Sam Altman

There's LogicFab capacity, there's how much HBM the world can make. There's how quickly you can get permits and pour the concrete, make the data centers, and then have people in there wiring them all up. There's finding the energy, which is a huge bottleneck. But I think when there's this much value to people, the world will do its thing. We'll try to help it happen faster.

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912.05 - 927.724 Sam Altman

And there's probably like I don't know how to give it a number, but there's some percentage chance where there is, as you were saying, a huge substrate breakthrough, and we have a massively more efficient way to do computing, but I don't bank on that or spend too much time thinking about it.

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928.641 - 944.132 Chamath Palihapitiya

What about the device side? And sort of, you mentioned sort of the models that can fit on a phone. So obviously, whether that's an LLM or some SLM or something, I'm sure you're thinking about that. But then does the device itself change? I mean, does it need to be as expensive as an iPhone?

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948.215 - 977.337 Sam Altman

I'm super interested in this. I love like great new form factors of computing. And it feels like with every major technological advance, a new thing becomes possible. Phones are unbelievably good, so I think the threshold is very high here. I personally think an iPhone is the greatest piece of technology humanity has ever made. It's really a wonderful product. What comes after it? I don't know.

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978.258 - 983.462 Sam Altman

That was what I was saying. It's so good to get beyond it. I think the bar is quite high.

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984.175 - 986.736 Jason Calacanis

Well, you've been working with Johnny Ive on something, right?

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986.796 - 990.956 Sam Altman

We've been discussing ideas, but I don't, like, if I knew.

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991.576 - 995.757 Chamath Palihapitiya

Is it that that it has to be more complicated or actually just much, much cheaper and simpler?

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996.557 - 1012.841 Sam Altman

Well, almost everyone's willing to pay for a phone anyway. So if you could, like, make a way cheaper device, I think the barrier to carry a second thing or use a second thing is pretty high. So I don't think, given that we're all willing to pay for phones, or most of us are, I don't think cheaper is the answer.

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1014.471 - 1015.491 Jason Calacanis

Different is the answer then?

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1016.712 - 1023.434 David Sacks

Would there be like a specialized chip that would run on the phone that was really good at powering a phone size AI model?

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1023.734 - 1040.092 Sam Altman

Probably, but the phone manufacturers are going to do that for sure. That doesn't necessitate a new device. I think you'd have to find some really different interaction paradigm that the technology enables. And if I knew what it was, I would be excited to be working on it right now.

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1040.152 - 1053.155 Jason Calacanis

Well, you have voice working right now in the app. In fact, I set my action button on my phone to go directly to ChatGPT's voice app, and I use it with my kids, and they love it, talking to it. It's got latency issues, but it's really great.

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1053.295 - 1065.901 Sam Altman

We'll get that better. And I think voice is a hint to whatever the next thing is. If you can get voice interaction to be really good, it feels great. I think that feels like a different way to use a computer.

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1066.302 - 1080.888 Jason Calacanis

But again, like we already- Let's talk about that, by the way. Like why is it not responsive and- you know, it feels like a CB, you know, like over, over. It's really annoying to use, you know, in that way. But it's also brilliant when it gives you the right answer.

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1081.188 - 1092.657 Sam Altman

We are working on that. It's so clunky right now. It's slow. It's like kind of doesn't feel very smooth or authentic or organic. Like we'll get all that to be much better.

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1094.078 - 1108.306 David Sacks

What about computer vision? I mean, they have glasses or maybe you could wear a pendant. I mean, you take the combination of visual or video data, combine it with voice, and now the AI knows everything that's happening around you.

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1108.386 - 1127.536 Sam Altman

Super powerful to be able to like, the multimodality of saying like, hey, ChatGPT, what am I looking at? Or like, what kind of plant is this? I can't quite tell. That's another, I think, hint, but whether people want to wear glasses or hold up something when they want that,

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1129.604 - 1138.25 Sam Altman

There's a bunch of just like the sort of like societal interpersonal issues here are all very complicated about wearing a computer on your face.

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1139.311 - 1143.854 David Sacks

We saw that with Google Glass. People got punched in the face in the mission. Started a lot of fights.

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1143.874 - 1146.496 Sam Altman

I forgot about that. I forgot about that. So I think it's like.

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1148.898 - 1158.765 David Sacks

What are the apps that could be unlocked if AI was sort of ubiquitous on people's phones? Do you have a sense of that or what would you want to see built?

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1162.892 - 1188.611 Sam Altman

I think what I want is just this always on like super low friction thing where I can... either by voice or by text or ideally like some other, it just kind of knows what I want, have this like constant thing helping me throughout my day that's got like as much context as possible. It's like the world's greatest assistant. And it's just this like thing working to make me better and better.

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1189.432 - 1195.077 Sam Altman

There's like a, I know when you hear people like talk about the AI future, they imagine there's sort of two things

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1197.799 - 1223.943 Sam Altman

different approaches and they don't sound that different but I think they're like very different for how we'll design the system in practice there's the I want an extension of myself I want like a ghost or an alter ego or this thing that really like is me is acting on my behalf is responding to emails not even telling me about it is sort of like It becomes more me and is me.

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1224.463 - 1247.257 Sam Altman

And then there's this other thing, which is like, I want a great senior employee. It may get to know me very well. I may delegate it. You know, you can like have access to my email and I'll tell you the constraints, but I think of it as this like separate entity. And I personally like the separate entity approach better and think that's where we're gonna head. And so in that sense,

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1249.588 - 1257.134 Sam Altman

The thing is not you, but it's like a always available, always great, super capable assistant executive.

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1257.194 - 1265.301 Jason Calacanis

It's an agent in a way, like it's out there working on your behalf and understands what you want and anticipates what you want is what I'm reading into what you're saying.

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1265.381 - 1293.802 Sam Altman

I think there'd be agent-like behavior, but there's like a difference between a senior employee and an agent. And like I want it, you know, I think of like my, I think like a bit, Like one of the things that I like about a senior employee is they'll push back on me. They will sometimes not do something I ask or they sometimes will say like, I can do that thing if you want.

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1293.822 - 1305.611 Sam Altman

But if I do it, here's what I think would happen and then this and then that. And are you really sure? Yeah. I definitely want that kind of vibe, which not just like this thing that I give a task and it blindly does. It can reason.

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1306.032 - 1307.113 Jason Calacanis

Yeah. Yeah, and push back.

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1307.173 - 1315.866 Sam Altman

It can reason. It has like the kind of relationship with me that I would expect out of a really competent person that I worked with, which is different from like a sycophant.

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1316.126 - 1316.287 Chamath Palihapitiya

Yeah.

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1317.017 - 1330.163 Chamath Palihapitiya

The thing in that world where if you had this like Jarvis-like thing that can reason, what do you think it does to products that you use today where the interface is very valuable?

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1330.303 - 1345.531 Chamath Palihapitiya

So for example, if you look at an Instacart or if you look at an Uber or if you look at a DoorDash, these are not services that are meant to be pipes that are just providing a set of APIs to a smart set of agents that ubiquitously work on behalf of 8 billion people.

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1346.957 - 1356.204 Chamath Palihapitiya

What do you think has to change in how we think about how apps need to work, of how this entire infrastructure of experiences need to work in a world where you're agentically interfacing to the world?

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1356.524 - 1383.158 Sam Altman

I'm actually very interested in designing a world that is equally usable by humans and by AIs. So I... I like the interpretability of that. I like the smoothness of the handoffs. I like the ability that we can provide feedback or whatever. So, you know, DoorDash could just expose some API to my future AI assistant and they could go put the order in or whatever.

0
💬 0

1383.94 - 1407.514 Sam Altman

Or I could say, I could be holding my phone and I could say, okay, AI assistant, you put in this order on DoorDash, please. And I could watch the app open and see the thing clicking around and I could say, hey, no, not this. There's something about designing a world that is usable equally well by humans and AIs that I think is an interesting concept.

0
💬 0

1408.074 - 1418.178 Sam Altman

Same reason I'm more excited about humanoid robots than sort of robots of very other shapes. The world is very much designed for humans, and I think we should absolutely keep it that way. And a shared interface is nice.

0
💬 0

1419.384 - 1428.947 Jason Calacanis

So you see voice, chat, that modality kind of gets rid of apps. You just ask it for sushi. It knows sushi you liked before. It knows what you don't like and does its best shot at doing it.

0
💬 0

1430.268 - 1445.929 Sam Altman

It's hard for me to imagine that we just go to a world totally where you say like, hey, ChatGPT, order me sushi. And it says, okay, do you want it from this restaurant? What kind, what time, whatever? I think... I think visual user interfaces are super good for a lot of things.

0
💬 0

1447.57 - 1459.355 Sam Altman

And it's hard for me to imagine a world where you never look at a screen and just use voice mode only, but I can imagine that for a lot of things.

0
💬 0

1460.228 - 1469.975 Jason Calacanis

I mean, Apple tried with Siri. Supposedly, you can order an Uber automatically with Siri. I don't think anybody's ever done it because it's... Why would you take the risk of not putting it in your phone?

0
💬 0

1470.095 - 1485.865 Chamath Palihapitiya

To your point, the quality is not good. But when the quality is good enough, you'll actually prefer it just because it's just lighter weight. You don't have to take your phone out. You don't have to search for your app and press it. Oh, it automatically logged you out. Oh, hold on, log back in. Oh, TFA. It's a whole pain in the ass.

0
💬 0

1485.925 - 1491.548 Sam Altman

You know, it's like setting a timer with Siri, I do every time because it... works really well. And it's great.

0
💬 0

1491.728 - 1492.469 Chamath Palihapitiya

More information.

0
💬 0

1493.309 - 1511.593 Sam Altman

But ordering an Uber, like, I want to see the prices for a few different options, I want to see how far away it is, I want to see like, maybe even where they are on the map, because I might walk somewhere, I get a lot more information by, I think, in less time by looking at that order the Uber screen than I would if I had to do that all through the audio channel.

0
💬 0

1512.393 - 1514.653 Jason Calacanis

So idea of watching it happen. That's kind of cool.

0
💬 0

1515.534 - 1522.367 Sam Altman

I think there will just be like, yeah, different There are different interfaces we use for different tasks, and I think that'll keep going.

0
💬 0

1522.687 - 1538.612 Chamath Palihapitiya

Of all the developers that are building apps and experiences on OpenAI, are there a few that stand out for you where you're like, okay, this is directionally going in a super interesting area, even if it's like a toy app. But are there things that you guys point to and say, this is really important?

0
💬 0

1541.478 - 1562.923 Sam Altman

I met with a new company this morning or barely even a company. It's like two people that are going to work on a summer project trying to actually finally make the AI tutor. And I've always been interested in this space. A lot of people have done great stuff on our platform. But if someone can deliver like the way that you actually like.

0
💬 0

1564.722 - 1584.588 Sam Altman

They used a phrase I love, which is this is going to be like a Montessori level reinvention for how people learn things. But if you can find this new way to let people explore and learn in new ways on their own, I'm personally super excited about that. A lot of the coding-related stuff you mentioned, Devin, earlier, I think that's like a super cool vision of the future.

0
💬 0

1585.048 - 1612.249 Sam Altman

The thing that I am, healthcare, I believe, should be pretty transformed by this. But the thing I'm personally most excited about is the sort of doing faster and better scientific discovery. GPT-4 clearly not there in a big way, although maybe it accelerates things a little bit by making scientists more productive. But alpha 43, yeah. That's like... But Sam... That will be a triumph.

0
💬 0

1612.409 - 1637.977 David Friedberg

Those are not... Like these models are trained... and built differently than the language models. I mean, to some, obviously there's a lot that's similar, but there's a lot, there's kind of a ground up architecture to a lot of these models that are being applied to these specific problem sets, these specific applications like chemistry interaction modeling, for example.

0
💬 0

1639.217 - 1653.046 Sam Altman

You'll need some of that for sure. But the thing that I think we're missing across the board for many of these things we've been talking about is models that can do reasoning. And once you have reasoning, you can connect it to chemistry stimulators or whatever else.

0
💬 0

1653.066 - 1669.59 David Friedberg

Yeah, that's the important question I wanted to kind of talk about today was this idea of networks of models. People talk a lot about agents as if there's kind of this linear set of call functions that happen. But one of the things that arises...

0
💬 0

1671.058 - 1683.765 David Friedberg

in biology is networks of systems that have cross interactions that the aggregation of the system, the aggregation of the network produces an output rather than one thing calling another, that thing calling another.

0
💬 0

1684.366 - 1701.835 David Friedberg

Do we see like an emergence in this architecture of either specialized models or network models that work together to address bigger problem sets, use reasoning, there's computational models that do things like chemistry or arithmetic, and there's other models that do, rather than one model to rule them all that's purely generalized?

0
💬 0

1705.016 - 1705.456 Chamath Palihapitiya

I don't know.

0
💬 0

1709.678 - 1723.003 Sam Altman

I don't know how much reasoning is going to turn out to be a super generalizable thing. I suspect it will, but that's more just like an intuition and a hope, and it would be nice if it worked out that way. I don't know if that's like...

0
💬 0

1726.428 - 1729.589 Chamath Palihapitiya

But let's walk through the protein modeling example.

0
💬 0

1730.929 - 1751.735 David Friedberg

There's a bunch of training data, images of proteins, and then sequence data, and they build a model, predictive model, and they have a set of processes and steps for doing that. Do you envision that there's this artificial general intelligence or this great reasoning model that then figures out how to build that sub model that figures out how to solve that problem by acquiring the necessary data

0
💬 0

1752.879 - 1766.151 Sam Altman

There's so many ways where that could go. Maybe it trains a literal model for it, or maybe it just knows the one big model. It can go pick what other training data it needs and ask a question and then update on that.

0
💬 0

1768.191 - 1783.643 David Friedberg

I guess the real question is, are all these startups going to die? Because so many startups are working in that modality, which is go get special data and then train a new model on that special data from the ground up. And then it only does that one sort of thing. And it works really well at that one thing. And it works better than anything else at that one.

0
💬 0

1783.663 - 1807.453 Sam Altman

You know, there's like a version of this. I think you can like... already see. When you were talking about biology and these complicated networks of systems, the reason I was smiling, I got super sick recently, and I'm mostly better now, but it was just like, body got beat up, one system at a time. You can really tell, okay, it's this cascading thing, and

0
💬 0

1809.468 - 1832.195 Sam Altman

And that reminded me of you talking about biology is just these, you have no idea how much these systems interact with each other until things start going wrong. And that was sort of interesting to see. But I was using ChatGPT to try to figure out what was happening, whatever, and would say, well, I'm unsure of this one thing. And then I just posted a paper

0
💬 0

1833.064 - 1850.134 Sam Altman

on it without even reading the paper, like in the context. And it says, oh, that was the thing I wasn't sure of. Like now I think this instead. So there's like a, that was like a small version of what you're talking about, where you can like, can say this, I don't know this thing. And you can put more information. You don't retrain the model, you're just adding it to the context here.

0
💬 0

1851.075 - 1874.897 David Friedberg

And now you're getting a. So these models that are predicting protein structure, like let's say, right, this is the whole basis. And now other molecules at AlphaFold3, Can they... Yeah, I mean, is it basically a world where the best generalized model goes in and gets that training data and then figures out on its own? And maybe you could use an example for us.

0
💬 0

1874.937 - 1887.444 David Friedberg

Can you tell us about Sora, your video model that generates amazing moving images, moving video? And what's different about the architecture there, whatever you're willing to share, on how that is different?

0
💬 0

1888.425 - 1918.17 Sam Altman

Yeah, so my... On the general thing first, my... You clearly will need specialized simulators, connectors, pieces of data, whatever. But my intuition, and again, I don't have this like backed up with science. My intuition would be if we can figure out the core of generalized reasoning, connecting that to new problem domains in the same way that humans are generalized reasoners.

0
💬 0

1919.992 - 1921.933 Sam Altman

would, I think, be doable.

0
💬 0

1922.313 - 1926.314 David Friedberg

It's like a faster unlock. I think so.

0
💬 0

1931.036 - 1943.56 Sam Altman

But yeah, Sora does not start with a language model. That's a model that is customized to do video. And so we're clearly not at that world yet.

0
💬 0

1944.099 - 1965.446 David Friedberg

Right. So just as an example, for you guys to build a good video model, you built it from scratch using, I'm assuming, some different architecture and different data. But in the future, the generalized reasoning system, the AGI, whatever system, theoretically could render that by figuring out how to do it.

0
💬 0

1966.287 - 1978.913 Sam Altman

Yeah, I mean, one example of this is like, okay, you know, as far as I know, all the best text models in the world are still autoregressive models, and the best image and video models are diffusion models. That's like sort of strange in some sense.

0
💬 0

1979.795 - 1979.995 Chamath Palihapitiya

Yeah.

0
💬 0

1980.576 - 2004.651 Jason Calacanis

So there's a big debate about training data. You guys have been, I think, the most thoughtful of any company. You've got licensing deals now, FT, et cetera. And we got to just be gentle here because you're involved in a New York Times lawsuit. You weren't able to settle, I guess, an arrangement with them for training data. How do you think about fairness in fair use

0
💬 0

2005.992 - 2032.629 Jason Calacanis

we've had big debates here on the pod. Obviously, your actions speak volumes that you're trying to be fair by doing licensing deals. So what's your personal position on the rights of artists who create beautiful music, lyrics, books, and you taking that and then making a derivative product out of it and then monetizing it? And what's fair here? And how do we get to a world where

0
💬 0

2033.65 - 2049.843 Jason Calacanis

you know, artists can make content in the world and then decide what they want other people to do with it. Yeah. And I'm just curious, your personal belief, because I know you to be a thoughtful person on this. And I know a lot of other people in our industry are not very thoughtful about how they think about content creators.

0
💬 0

2051.109 - 2077.913 Sam Altman

So I think it's very different for different kinds of, I mean, look, on unfair use, I think we have a very reasonable position under the current law, but I think AI is so different that for things like art, we'll need to think about them in different ways. I would say if you go read a bunch of math on the internet and learn how to do math, that I think seems unobjectionable to most people.

0
💬 0

2078.273 - 2094.316 Sam Altman

And then there's another set of people who might have a different opinion. Well, what if you like Actually, let me not get into that, just in the interest of not making this answer too long. So I think there's one category people are like, okay, there's generalized human knowledge.

0
💬 0

2094.436 - 2107.88 Sam Altman

You can kind of go, if you learn that, that's open domain or something, if you kind of go learn about the Pythagorean theorem. That's one end of the spectrum. And then I think the other extreme end of the spectrum is...

0
💬 0

2110.262 - 2129.724 Sam Altman

is art, and maybe even like more than, more specifically I would say it's like doing, it's a system generating art in the style or the likeness of another artist would be kind of the furthest end of that. And then there's many, many cases on the spectrum in between.

0
💬 0

2132.034 - 2154.883 Sam Altman

I think the conversation has been historically very caught up on training data, but it will increasingly become more about what happens at inference time. As training data becomes less valuable and what the system does accessing information in context in real time or...

0
💬 0

2157.525 - 2172.585 Sam Altman

you know, taking like something like that, what happens at inference time will become more debated and what the new economic model is there. So if you say like, if you say like, create me a song in the style of Taylor Swift,

0
💬 0

2175.023 - 2197.785 Sam Altman

even if the model were never trained on any Taylor Swift songs at all, you can still have a problem, which is it may have read about Taylor Swift, it may know about her themes, Taylor Swift means something. And then the question is, should that model, even if it were never trained on any Taylor Swift song whatsoever, be allowed to do that? And if so, How should Taylor get paid? Right.

0
💬 0

2198.246 - 2216.263 Sam Altman

So I think there's an opt-in, opt-out in that case, first of all, and then there's an economic model. Staying on the music example, there is something interesting to look at from... the historical perspective here, which is sampling and how the economics around that work. This is not quite the same thing, but it's like an interesting place to start looking.

0
💬 0

2216.283 - 2235.227 David Friedberg

Sam, let me just challenge that. What's the difference in the example you're giving of the model learning about things like song structure, tempo, melody, harmony relationships, discovering all the underlying structure that makes music successful, and then building new music using training data?

0
💬 0

2236.107 - 2257.492 David Friedberg

and what a human does, that listens to lots of music, learns about, and their brain is processing and building all those same sort of predictive models or those same sort of discoveries or understandings. What's the difference here? And why are you making the case that perhaps artists should be uniquely paid. This is not a sampling situation.

0
💬 0

2257.872 - 2263.694 David Friedberg

The AI is not outputting and it's not storing in the model the actual original song. It's learning structure.

0
💬 0

2264.174 - 2273.977 Sam Altman

I wasn't trying to make that point because I agree in the same way that humans are inspired by other humans. I was saying if you say generate me a song in the style of Taylor Swift.

0
💬 0

2274.177 - 2274.777 David Friedberg

I see. Right.

0
💬 0

2275.357 - 2275.898 Sam Altman

Okay.

0
💬 0

2275.998 - 2277.958 David Friedberg

Where the prompt leverages some artist.

0
💬 0

2278.838 - 2280.619 Sam Altman

I think personally that's a different case.

0
💬 0

2281.004 - 2299.671 David Friedberg

Would you be comfortable asking, or would you be comfortable letting the model train itself, a music model being trained on the whole corpus of music that humans have created without royalties being paid to the artists that that music is being fed in? And then you're not allowed to ask, you know, artist specific prompts.

0
💬 0

2299.711 - 2306.734 David Friedberg

You could just say, hey, play me a really cool pop song that's fairly modern about heartbreak, you know, with a female voice, you know?

0
💬 0

2307.134 - 2328.282 Sam Altman

We have currently made the decision not to do music, and partly because exactly these questions of where you draw the lines. I was meeting with several musicians I really admire recently, and I was just trying to talk about some of these edge cases. But even the world in which... If we...

0
💬 0

2329.83 - 2351.927 Sam Altman

went and let's say we paid 10,000 musicians to create a bunch of music just to make a great training set where the music model could learn everything about strong structure and what makes a good catchy beat and everything else. And only trained on that. Let's say we could still make a great music model, which maybe we could.

0
💬 0

2353.408 - 2370.862 Sam Altman

You know, I was kind of like posing that as a thought experiment to musicians. And they're like, well, I can't object to that on any principle basis at that point. And yet there's still something I don't like about it. Now, that's not a reason not to do it necessarily. But it is. Did you see that ad that Apple put out?

0
💬 0

2371.043 - 2375.746 Sam Altman

Maybe it was yesterday or something of like squishing all of human creativity down into one really thin iPad.

0
💬 0

2375.766 - 2380.888 David Sacks

What was your take on it? People got really emotional about it, yeah.

0
💬 0

2381.268 - 2381.688 Sam Altman

Yeah.

0
💬 0

2381.708 - 2383.249 David Sacks

Stronger reaction than you would think.

0
💬 0

2383.89 - 2409.444 Sam Altman

There's something about... I'm obviously hugely positive on AI, but there is something that I think is beautiful about human creativity and human artistic expression. And, you know, for an AI that just does better science, like, great, bring that on. But an AI that is going to do this, like, deeply beautiful human creative expression, I think we should, like... figure out it's going to happen.

0
💬 0

2410.084 - 2417.65 Sam Altman

It's going to be a tool that will lead us to greater creative heights. But I think we should figure out how to do it in a way that preserves the spirit of what we all care about here.

0
💬 0

2418.491 - 2434.725 Jason Calacanis

And I think your actions speak loudly. We were trying to do Star Wars characters in Dali. And if you ask for Darth Vader, it says, hey, we can't do that. So you've, I guess, red teamed or whatever you call it internally. We try.

0
💬 0

2434.745 - 2434.825 Sam Altman

Yeah.

0
💬 0

2435.265 - 2449.48 Jason Calacanis

Yeah, you're not allowing people to use other people's IP. So you've taken that decision. Now, if you asked it to make a Jedi bulldog, or a Sith Lord bulldog, which I did, it made my bulldogs as Sith bulldogs. So there's an interesting question about like, right?

0
💬 0

2449.64 - 2473.691 Sam Altman

Yeah, you know, we put out this thing yesterday called the spec, where we're trying to say here are, here's, here's how our model is supposed to behave. And it's very hard, it's a long document, it's very hard to specify exactly in each case where the limits should be, and I view this as a discussion that's gonna need a lot more input. But these sorts of questions about

0
💬 0

2475.276 - 2485.459 Sam Altman

okay, maybe it shouldn't generate Darth Vader, but the idea of a Sith Lord or a Sith-style thing or Jedi at this point is part of the culture. These are all hard decisions.

0
💬 0

2485.999 - 2510.786 Jason Calacanis

Yeah, and I think you're right. The music industry is going to consider this opportunity to make Taylor Swift songs their opportunity. It's part of the four-part fair use test is who gets to capitalize on new innovations for existing art. And Disney has an argument that, hey, you know, If you're going to make Sora versions of Ashoka or whatever, Obi-Wan Kenobi, that's Disney's opportunity.

0
💬 0

2511.026 - 2515.388 Jason Calacanis

And that's a great partnership for you to pursue.

0
💬 0

2515.888 - 2528.893 Chamath Palihapitiya

So I think this section I would label as AI and the law. So let me ask maybe a higher level question. What does it mean when people say regulate AI? Totally. Sam, what does that even mean?

0
💬 0

2529.252 - 2535.316 David Friedberg

And comment on California's new proposed regulations as well if you're up for it.

0
💬 0

2535.516 - 2552.658 Sam Altman

I'm concerned. I mean, there's so many proposed regulations, but most of the ones I've seen on the California state things I'm concerned about. I also have a general fear of the states all doing this themselves. When people say regulate AI, I don't think... they mean one thing. I think there's like, some people are like, ban the whole thing.

0
💬 0

2553.238 - 2569.018 Sam Altman

Some people are like, don't allow it to be open source, require it to be open source. The thing that I am personally most interested in is I think there will come Look, I may be wrong about this. I will acknowledge that this is a forward-looking statement and those are always dangerous to make.

0
💬 0

2569.118 - 2583.809 Sam Altman

But I think there will come a time in the not super distant future, like, you know, we're not talking like decades and decades from now, where the frontier AI systems are capable of causing significant damage global harm.

0
💬 0

2584.73 - 2606.382 Sam Altman

And for those kinds of systems, in the same way we have global oversight of nuclear weapons or synthetic bio or things that can really have a very negative impact way beyond the realm of one country, I would like to see some sort of international agency that is looking at the most powerful systems and ensuring reasonable safety testing.

0
💬 0

2606.982 - 2610.704 Sam Altman

These things are not going to escape and recursively self-improve or whatever.

0
💬 0

2611.482 - 2634.732 Jason Calacanis

The criticism of this is that you have the resources to cozy up, to lobby, to be involved, and you've been very involved with politicians, and then startups, which you're also passionate about and invest in, are not going to have the ability to resource and deal with this, and that this regulatory capture, as per our friend You know, Bill Gurley did a great talk last year about it.

0
💬 0

2634.772 - 2636.373 Jason Calacanis

So maybe you could address that head on.

0
💬 0

2636.694 - 2652.281 Sam Altman

Do you feel like if the line where we're only going to look at models that are trained on computers that cost more than 10 billion or more than 100 billion or whatever dollars, I'd be fine with that. There'd be some line that'd be fine. And I don't think that puts any regulatory burden on startups.

0
💬 0

2652.461 - 2666.555 Jason Calacanis

So if you have the nuclear raw material to make a nuclear bomb, there's a small subset of people who have that. Therefore, you use the analogy of a nuclear inspector kind of situation. Yeah. I think that's interesting. Sax, you have a question?

0
💬 0

2666.676 - 2679.954 Sam Altman

Well, Chamath, go ahead. You had a follow-up. Can I say one more thing about that? Of course. I'd be super nervous about regulatory overreach here. I think we can get this wrong by doing way too much, or even a little too much. I think we can get this wrong by doing not enough.

0
💬 0

2680.695 - 2707.556 Sam Altman

But I do think part of... And now, I mean, we have seen regulatory overstepping or capture just get super bad in other areas. And... you know, also maybe nothing will happen. But I think it is part of our duty and our mission to like talk about what we believe is likely to happen and what it takes to get that right.

0
💬 0

2708.069 - 2735.728 David Friedberg

The challenge, Sam, is that we have statute that is meant to protect people, protect society at large. What we're creating, however, is statute that gives the government rights to go in and audit code, to audit business trade secrets. We've never seen that to this degree before. Basically, the California legislation that's proposed and some of the federal legislation that's been proposed

0
💬 0

2736.741 - 2754.553 David Friedberg

basically requires the government to audit a model, to audit software, to audit and review the parameters and the weightings of the model. And then you need their check mark in order to deploy it for commercial or public use. And for me, it just feels like

0
💬 0

2755.543 - 2771.766 David Friedberg

We're trying to rein in the government agencies for fear and because folks have a hard time understanding this and are scared about the implications of it, they want to control it. And the only way to control it is to say, give me a right to audit before you can release it.

0
💬 0

2771.866 - 2774.167 David Sacks

Yeah, and they're clueless. These people are clueless.

0
💬 0

2774.187 - 2781.368 David Friedberg

I mean, the way that the stuff is written, you read it, you're like going to pull your hair out because as you know better than anyone, in 12 months, none of this stuff is going to make sense anyway.

0
💬 0

2781.528 - 2801.154 Sam Altman

Totally. Right. Look, the reason I have pushed for... an agency-based approach for kind of like the big picture stuff and not a like write it in laws. I don't, in 12 months, it will all be written wrong. And I don't think, even if these people were like true world experts, I don't think they could get it right looking at 12 or 24 months.

0
💬 0

2801.934 - 2814.345 Sam Altman

And I don't, these policies, which is like, we're going to look at, you know, we're going to audit all of your source code and like look at all of your weights one by one. Like, I think there's a lot of crazy proposals out there.

0
💬 0

2815.525 - 2819.066 David Friedberg

By the way, especially if the models are always being retrained all the time, if they become more dynamic.

0
💬 0

2819.206 - 2831.93 Sam Altman

Again, this is why I think it's... But, like, when... Before an airplane gets certified, there's, like, a set of safety tests. We put the airplane through it, and... Totally. It's different than reading all of your code.

0
💬 0

2832.09 - 2836.191 David Friedberg

That's reviewing the output of the model, not reviewing the insides of the model.

0
💬 0

2837.311 - 2844.174 Sam Altman

And so what I was going to say is that is the kind of... that I think as safety testing makes sense.

0
💬 0

2844.595 - 2865.708 David Friedberg

How are we going to get that to happen, Sam? And I'm not just speaking for OpenAI, I speak for the industry, for humanity, because I am concerned that we draw ourselves into almost like a dark ages type of era by restricting the growth of these incredible technologies that humanity can prosper from so significantly. How do we change the sentiment and get that to happen?

0
💬 0

2865.728 - 2871.391 David Friedberg

Because this is all moving so quickly at the government levels. And folks seem to be getting it wrong. And I'm personally concerned.

0
💬 0

2871.411 - 2890.839 Chamath Palihapitiya

Just to build on that, Sam, the architectural decision, for example, that Lama took is pretty interesting in that it's like, we're going to let Lama grow and be as unfettered as possible. And we have this other kind of thing that we call Lama guard that's meant to be these protective guardrails. Is that how you see the problem being solved correctly?

0
💬 0

2891.119 - 2911.603 Sam Altman

Or do you see that... At the current strength of models... Definitely some things are going to go wrong, and I don't want to make light of those or not take those seriously. But I don't have any catastrophic risk worries with a GPT-4 level model. And I think there's many safe ways to choose to deploy this.

0
💬 0

2915.895 - 2946.391 Sam Altman

Maybe we'd find more common ground if we said that, like, you know, the specific example of models that are capable, that are technically capable, even if they're not going to be used this way, of recursive self-improvement or of, you know, autonomously designing and deploying a bioweapon or something like that. Or a new model. Yeah. That was the recursive self-improvement point.

0
💬 0

2946.471 - 2959.218 Sam Altman

We should have safety testing on the outputs at an international level for models that have a reasonable chance of posing a threat there. I don't think GPT-4, of course, does not...

0
💬 0

2963.54 - 2984.797 Sam Altman

pose it in any sort of well, I don't say any sort because We don't yeah, I don't think the GPT-4 poses a material threat on those kinds of things And I think there's many safe ways to release a model like this but you know when like significant loss of human life is a serious possibility like airplanes or

0
💬 0

2986.92 - 2993.647 Sam Altman

any number of other examples where I think we're happy to have some sort of testing framework. Like I don't think about an airplane when I get on it. I just assume it's going to be safe.

0
💬 0

2994.087 - 3003.636 Jason Calacanis

Right. There's a lot of hand-wringing right now, Sam, about jobs. And you had a lot of, I think you did like some sort of a test when you were at YC about UBI.

0
💬 0

3004.297 - 3014.574 Sam Altman

Our results on that come out very soon. It was a five-year study that wrapped up or started five years ago. Well, there was like a beta study first and then it was like a long one that ran.

0
💬 0

3015.275 - 3019.998 David Friedberg

But- Well, Mark, what did you learn about that? Yeah, why'd you start it? Maybe just explain UBI and why you started it.

0
💬 0

3022.004 - 3053.262 Sam Altman

So we started thinking about this in 2016, kind of about the same time, started taking AI really seriously. And the theory was that the magnitude of the change that may come to society and jobs and the economy, and sort of in some deeper sense than that, like what the social contract looks like, meant that we should have many studies to study many ideas about new ways to arrange that.

0
💬 0

3053.923 - 3077.048 Sam Altman

I also think that I'm not a super fan of how the government has handled most policies designed to help poor people. And I kind of believe that if you could just give people money, they would make good decisions and the market would do its thing. And, you know, I'm very much in favor of lifting up the floor and reducing, eliminating poverty.

0
💬 0

3077.869 - 3101.687 Sam Altman

But I'm interested in better ways to do that than what we have tried for the existing social safety net and kind of the way things have been handled. And I think giving people money is not going to go solve all problems. It's certainly not going to make people happy, but it might solve some problems and it might give people a better horizon with which to help themselves.

0
💬 0

3101.747 - 3129.253 Sam Altman

And I'm interested in that. I think that now that we see some of the ways, so 2016 was a very long time ago. Now that we see some of the ways that AI is developing, I wonder if there's better things to do than the traditional way conceptualization of UBI. Like I wonder, I wonder if the future looks something like, more like universal basic compute than universal basic income.

0
💬 0

3129.853 - 3144.041 Sam Altman

And everybody gets like a slice of GPT-7's compute and they can use it, they can resell it, they can donate it to somebody to use for cancer research. But what you get is not dollars, but this like, slice. Yeah, you own like part of the productivity.

0
💬 0

3144.321 - 3146.783 Chamath Palihapitiya

Right. I would like to shift to the gossip part of this.

0
💬 0

3147.684 - 3147.864 Sam Altman

Okay.

0
💬 0

3147.884 - 3154.35 Chamath Palihapitiya

Gossip? What gossip? Sam, let's go back to November. What the flying f*** happened?

0
💬 0

3156.832 - 3164.476 Sam Altman

Um... You know, I, if you have specific questions, I'm happy to maybe I said, maybe I want to talk about it at some point.

0
💬 0

3164.576 - 3167.096 David Sacks

So here's the point. What happened?

0
💬 0

3167.376 - 3176.699 Jason Calacanis

You were fired, you came back and it was palace intrigue. Did somebody stab you in the back? Did you find AGI? What's going on? This is a safe space.

0
💬 0

3176.819 - 3207.913 Sam Altman

I was fired. I was I talked about coming back. I kind of was a little bit unsure at the moment about what I wanted to do because I was very upset. And I realized that I really loved OpenAI and the people and that I would come back. And I kind of I knew it was going to be hard. It was even harder than I thought. But I kind of was like, all right, fine. I agreed to come back.

0
💬 0

3209.433 - 3229.263 Sam Altman

The board like took a while to figure things out. And then, you know, we were kind of like, trying to keep the team together and keep doing things for our customers. And, you know, sort of started making other plans, then the board decided to hire a different interim CEO. And then everybody There are many people. Oh, my gosh.

0
💬 0

3229.303 - 3235.047 Chamath Palihapitiya

What was that guy's name? He was there for like a Scaramucci, right? Emmett's great.

0
💬 0

3235.167 - 3241.511 Sam Altman

And I have nothing but good things to say about Emmett. I was here for Scaramucci. And then.

0
💬 0

3241.932 - 3246.535 Jason Calacanis

Where were you when you found the news that you'd been fired? Take me to that moment.

0
💬 0

3246.715 - 3248.917 Sam Altman

I was in a hotel room in Vegas for F1 weekend.

0
💬 0

3249.417 - 3253.54 Jason Calacanis

I think that's happened to you before, J. Cal. So, you're there and they want you to get a text and they're like, fire, pick up the couch.

0
💬 0

3253.56 - 3255.081 David Sacks

I said, I think that's happened to you before, J. Cal. Yeah.

0
💬 0

3256.215 - 3262.299 Jason Calacanis

I'm trying to think if I ever got fired. I don't think I've gotten fired. Yeah, I got a text. No, it's just a weird thing. Like, it's a text from who?

0
💬 0

3262.819 - 3281.568 Sam Altman

Actually, no, I got a text the night before. And then I got on a phone call with the board. And then that was that. And then I kind of like, I mean, then everything went crazy. I was like, it was like. I mean, my phone was like unusable. It was just a nonstop vibrating thing of like text messages, calls.

0
💬 0

3281.748 - 3290.717 David Sacks

Basically, you got fired by tweet. That happened a few times during the Trump administration. A few cabinet appointments got tweeted out. They did call me first before tweeting.

0
💬 0

3290.757 - 3318.425 Sam Altman

It was nice of them. And then like, you know, I kind of did like a few hours of just this like absolute fugue state in the hotel room. trying to like I was just confused beyond belief trying to figure out what to do and so weird and then like Flew home at maybe like, I don't know, 3 p.m. or something like that. Still just like, you know, crazy nonstop phone blowing up.

0
💬 0

3319.285 - 3348.116 Sam Altman

Met up with some people in person. By that evening, I was like, okay, you know, I'll just like go do AGI research and was feeling pretty happy about the future. Yeah, you have options. And then the next morning, had this call with a couple of board members about coming back and that led to a few more days of craziness. And then, uh, and then it kind of, I think it got resolved.

0
💬 0

3349.037 - 3351.719 Sam Altman

Well, it was like a lot of insanity in between.

0
💬 0

3352.28 - 3355.643 David Sacks

What percent of it was because of these nonprofit board members?

0
💬 0

3357.204 - 3375.262 Sam Altman

Um, well, we only have a nonprofit board, so it was all the nonprofit board members. Uh, there, the board had gotten down to six people. Um, they, uh, And then they removed Greg from the board and then fired me. So, but it was like, you know.

0
💬 0

3375.282 - 3382.488 David Sacks

But I mean, like, was there a culture clash between the people on the board who had only nonprofit experience versus the people who had startup experience?

0
💬 0

3382.808 - 3388.032 David Friedberg

And maybe you can share a little bit about if you're willing to, the motivation behind the action, anything you can.

0
💬 0

3389.493 - 3425.239 Sam Altman

I think there's always been culture clashes at... Look, obviously... not all of those board members are my favorite people in the world, but I have serious respect for the gravity with which they treat AGI and the importance of getting AI safety right. And even if I stringently disagree with their decision making and actions, which I do, I have never once doubted their

0
💬 0

3426.676 - 3455.034 Sam Altman

integrity or commitment to the sort of shared mission of safe and beneficial AGI. You know, do I think they, like, made good decisions in the process of that or kind of know how to balance all the things OpenAI has to get right? No. But I think the, like... The intent. The intent of the magnitude of AGI and getting that right

0
💬 0

3456.284 - 3472.261 David Sacks

Actually, let me ask you about that. So the mission of OpenAI is explicitly to create AGI, which I think is really interesting. A lot of people would say that if we create AGI, that would be like an unintended consequence of something gone wrong.

0
💬 0

3472.762 - 3499.02 David Sacks

horribly wrong and they're very afraid of that outcome but open ai makes that the actual mission does that create like more fear about what you're doing i mean i understand it can create motivation too but how do you reconcile that i guess why i think a lot of i think a lot of the well i mean first i'll say i'll answer the first question in the second one i think it does create a great deal of fear i think a lot of the world is understandably

0
💬 0

3500.1 - 3523.614 Sam Altman

very afraid of AGI or very afraid of even current AI and very excited about it and even more afraid and even more excited about where it's going. And we We wrestle with that, but I think it is unavoidable that this is going to happen. I also think it's going to be tremendously beneficial. But we do have to navigate how to get there in a reasonable way.

0
💬 0

3524.215 - 3534.382 Sam Altman

And a lot of stuff is going to change, and change is pretty uncomfortable for people. So there's a lot of pieces that we got to get right.

0
💬 0

3534.402 - 3558.814 Chamath Palihapitiya

Can I ask a different question? You have created, I mean... It's the hottest company. And you are literally at the center of the center of the center. But then it's so unique in the sense that all of this value you eschewed economically. Can you just walk us through why?

0
💬 0

3558.914 - 3561.895 Sam Altman

Yeah, I wish I had taken equity so I never had to answer this question.

0
💬 0

3562.675 - 3568.517 David Sacks

If I could go back in time. Why don't they give you a grant now? Why doesn't the board just give you a big option grant like you deserve?

0
💬 0

3568.557 - 3572.818 Chamath Palihapitiya

Yeah, give you five points. What was the decision back then? Why was that so important?

0
💬 0

3572.838 - 3593.498 Sam Altman

The decision back then, the original reason was just the structure of our nonprofit. There was something about... yeah, okay, this is like nice from a motivations perspective, but mostly it was that our board needed to be a majority of disinterested directors. And I was like, that's fine, I don't need equity right now. I kind of...

0
💬 0

3595.865 - 3605.709 Chamath Palihapitiya

But in this weird way, now that you're running a company, yeah, it creates these weird questions of like, well, what's your real motivation?

0
💬 0

3605.729 - 3616.791 Sam Altman

One thing I have noticed, it's so deeply unimaginable to people to say, I don't really need more money. Like, and I get how toned up.

0
💬 0

3617.111 - 3619.813 Chamath Palihapitiya

I think people think it's a little bit of an ulterior motive.

0
💬 0

3619.853 - 3621.754 Sam Altman

Well, yeah, yeah, yeah. No, so it assumes.

0
💬 0

3621.834 - 3624.115 David Friedberg

It's like, what else is he doing on the side to make money?

0
💬 0

3624.635 - 3633.1 Sam Altman

If I were just trying to say, like, I'm going to try to make a trillion dollars with open AI, I think everybody would have an easier time and it wouldn't save me. It would save a lot of conspiracy theories.

0
💬 0

3633.58 - 3657.899 Jason Calacanis

Sam, this is the back channel. You are a great dealmaker. I've watched your whole career. I mean, you're just great at it. You got all these connections. You're really good at raising money. You're fantastic at it. And you got this Johnny Ive thing going. You're inhumane. You're investing in companies. You got the orb. You're raising $7 trillion to build fabs, all this stuff.

0
💬 0

3658.679 - 3680.244 Jason Calacanis

All of that put together, J. Cal loves fake news. I'm kind of being a little facetious here. Obviously, you're not raising $7 trillion, but maybe that's the market cap or something. Putting all that aside, the T was you're doing all these deals. They don't trust you because what's your motivation? You're end running. And what opportunities belong inside of OpenAI?

0
💬 0

3680.344 - 3686.085 Jason Calacanis

What opportunities should be Sam's? And this group of nonprofit people didn't trust you. Is that what happened? Yeah.

0
💬 0

3686.445 - 3696.607 Sam Altman

So the things like, you know, device companies or if we were doing some chip fab company, it's like those are not SAM project. Those would be like opening. I would get that equity. They would.

0
💬 0

3696.847 - 3698.427 Jason Calacanis

OK, that's not the public's perception.

0
💬 0

3699.147 - 3717.453 Sam Altman

Well, that's not like kind of the people like you who have to like commentate on this stuff all day's perception, which is fair because we haven't announced this stuff because it's not done. I don't think most people in the world like are thinking about this, but I agree it spins up a lot of conspiracies. conspiracy theories in like tech commentators.

0
💬 0

3717.773 - 3718.373 Jason Calacanis

Yeah, in a vacuum.

0
💬 0

3718.934 - 3731.745 Sam Altman

And if I could go back, yeah, I would just say like, let me take equity and make that super clear. And then everyone would be like, all right. Like I'd still be doing it because I really care about AGI and think this is like the most interesting work in the world. But it would at least hype check to everybody.

0
💬 0

3732.246 - 3737.362 Jason Calacanis

What's the chip project? That's a $7 trillion. And where did the $7 trillion number come from? It makes no sense.

0
💬 0

3737.402 - 3756.516 Sam Altman

I don't know where that came from, actually. I genuinely don't. I think the world needs a lot more AI infrastructure, a lot more than it's currently planning to build and with a different cost structure. The exact way for us to play there is we're still trying to figure that out. Got it.

0
💬 0

3756.536 - 3771.358 Chamath Palihapitiya

What's your preferred model of organizing open AI? Is it... sort of like the move fast, break things, highly distributed small teams, or is it more of this organized effort where you need to plan because you want to prevent some of these edge cases?

0
💬 0

3772.419 - 3788.173 Sam Altman

Oh, I have to go in a minute. It's not because... It's not to prevent the edge cases that we need to be more organized, but it is that these systems are so complicated and concentrating bets are so important. Like one...

0
💬 0

3790.083 - 3808.563 Sam Altman

You know, at the time, before it was, like, obvious to do this, you have, like, DeepMind or whatever has all these different teams doing all these different things, and they're spreading their bets out. And you had OpenAI say, we're going to, like, basically put the whole company and work together to make GPT-4. And that was, like, unimaginable for how to run an AI research lab. But it is...

0
💬 0

3809.639 - 3821.16 Sam Altman

I think what works, at a minimum, it's what works for us. So not because we're trying to prevent edge cases, but because we want to concentrate resources and do these big, hard, complicated things, we do have a lot of coordination on what we work on.

0
💬 0

3822.116 - 3826.038 Jason Calacanis

All right, Sam, I know you got to go. You've been great on the hour. Come back anytime.

0
💬 0

3826.438 - 3828.899 Sam Altman

Great talking to you guys. Yeah, it was fun. Thanks for coming out.

0
💬 0

3828.919 - 3832.48 Jason Calacanis

Thanks for being so open about it. We've been talking about it for like a year plus.

0
💬 0

3832.62 - 3840.383 Sam Altman

I'm really happy it finally happened. Yeah, it's awesome. I really appreciate it. I would love to come back on after our next major launch and I'll be able to talk more directly about some of these things.

0
💬 0

3840.403 - 3844.585 Jason Calacanis

Yeah, you got the Zoom link. Same Zoom link every week. Same time, same Zoom link. Drop it anytime.

0
💬 0

3844.985 - 3845.445 Sam Altman

Just drop it.

0
💬 0

3845.465 - 3847.186 Jason Calacanis

Just put it on your calendar. Come back to the game.

0
💬 0

3847.266 - 3849.046 Chamath Palihapitiya

Come back to the game. Yeah, come back to the game.

0
💬 0

3849.066 - 3854.991 Sam Altman

We haven't seen you at poker in a while. You know, I would love to play poker. It has been forever. That would be a lot of fun.

0
💬 0

3855.392 - 3872.73 Jason Calacanis

That famous hand where you and I were heads up. I don't rely on me? You and I were heads up and you went all in. I had a set, but there was a straight and a flush on the board. And I'm in the tank trying to figure out if I want to lose. This is back when we played small stakes. It might have been like...

0
💬 0

3873.631 - 3893.496 Jason Calacanis

5k pot or something and then chamath can't stay out of the pot and he starts taunting the two of us you should call you shouldn't call he's bluffing and i'm like i'm going i'm trying to figure out if i make the call here i make the call and uh it was like uh you had a really good hand and i just happen to have a set i think you had the top pair top kicker or something but

0
💬 0

3894.216 - 3897.079 Jason Calacanis

You made a great move because the board was so textured, almost like old bottom set.

0
💬 0

3897.339 - 3902.104 Chamath Palihapitiya

Sam has a great style of playing, which I would call Ram and Jam. Totally. You got to just get out of the way.

0
💬 0

3902.124 - 3907.389 Sam Altman

I don't really know if you, I don't know if you could say that about anybody else. I don't, I'm not going to.

0
💬 0

3907.569 - 3911.753 David Friedberg

You haven't seen Samad play in the last 18 months. It's a lot different.

0
💬 0

3911.873 - 3919.7 Jason Calacanis

It's so much fun now. I find that really hard to believe. Have you played Bomb Pots? I don't know what that is. Okay, you'll love it.

0
💬 0

3920.04 - 3920.601 Chamath Palihapitiya

We'll see you next time.

0
💬 0

3920.621 - 3921.642 Jason Calacanis

This place is nuts.

0
💬 0

3921.662 - 3922.102 Chamath Palihapitiya

Thank you.

0
💬 0

3922.162 - 3923.703 David Sacks

It's PLO. Sam, thank you.

0
💬 0

3923.723 - 3925.344 Chamath Palihapitiya

But you do two boards. And congrats.

0
💬 0

3925.364 - 3932.289 David Sacks

It's nuts on everything, honestly. Thank you so much. Thanks for coming on. Thanks, Dan. Let's have you back when the next F the Big launch. Sounds good. Please do. Cool. Bye.

0
💬 0

3933.27 - 3946.28 Jason Calacanis

Gentlemen, some breaking news here. All those projects, he said, are part of OpenAI. That's something people didn't know before this and a lot of confusion there. Shamath, what was your major takeaway from our hour with Sam?

0
💬 0

3946.941 - 3959.85 Chamath Palihapitiya

I think that these guys are going to be one of the four major companies that matter in this whole space. I think that that's clear. I think what's still unclear is where is the economics going to be?

0
💬 0

3959.93 - 3980.95 Chamath Palihapitiya

He said something very discreet, but I thought was important, which is, I think he basically, my interpretation is these models will roughly all be the same, but there's going to be a lot of scaffolding around these models that actually allow you to build these apps. So in many ways, that is like the open source movement. So even if the model itself is never open source.

0
💬 0

3981.21 - 4003.187 Chamath Palihapitiya

It doesn't much matter because you have to pay for the infrastructure, right? There's a lot of open source software that runs on Amazon. You still pay AWS something. So I think the right way to think about this now is the models will basically be all really good. And then it's all this other stuff that you'll have to pay for. The interface. Whoever builds all this other stuff

0
💬 0

4005.086 - 4007.787 Chamath Palihapitiya

is going to be in a position to build a really good business.

0
💬 0

4008.127 - 4016.81 Jason Calacanis

Freeberg, he talked a lot about reasoning. It seemed like that he kept going to reasoning and away from the language model. Did you note that and anything else that you noted in our hour with him?

0
💬 0

4017.13 - 4039.509 David Friedberg

Yeah, I mean, that's a longer conversation because there is a lot of talk about language models eventually evolving to be so generalizable that they can resolve problems pretty much like all intelligent function. And so the language model is the foundational model that yields AGI. But I think there's a lot of people that are different schools of thought on this. And how much...

0
💬 0

4040.532 - 4057.641 Chamath Palihapitiya

My other takeaway, I think, is that the, I think what he also seemed to indicate is there's like so many, like we're all so enraptured by LLMs, but there's so many things other than LLMs that are being baked and rolled by him and by other groups.

0
💬 0

4057.721 - 4075.476 Chamath Palihapitiya

And I think we have to pay some amount of attention to all those because that's probably where, and I think Freeberg, you tried to go there in your question, that's where reasoning will really come from is this mixture of experts approach. And so you're gonna have to think multi-dimensionally to reason, right? We do that, right? Do I cross the street or not in this point in time?

0
💬 0

4075.976 - 4091.004 Chamath Palihapitiya

You reason based on all these multi-inputs. And so there's all these little systems that go into making that decision in your brain. And if you use that as a simple example, there's all this stuff that has to go into making some experience being able to reason intelligently.

0
💬 0

4091.424 - 4095.286 Jason Calacanis

Sacks, you went right there with the corporate structure, the board.

0
💬 0

4097.006 - 4117.828 Jason Calacanis

and uh he he gave us a lot more information here what are your thoughts on the hey you know the chip stuff and the other stuff i'm working on that's all part of open ai people just don't realize it and that moment and then you know your questions to him about equity your thoughts on um i'm not sure i was like the main guy who asked that question jacob but um

0
💬 0

4119.048 - 4123.671 Jason Calacanis

Well, no, you do talk about the nonprofit, the difference between the nonprofit.

0
💬 0

4123.791 - 4135.518 David Sacks

There clearly was some sort of culture clash on the board between the people who originated from the nonprofit world and the people who came from the startup world. We don't really know more than that, but there clearly was some sort of culture clash.

0
💬 0

4136.306 - 4157.065 David Sacks

I thought a couple of the other areas that he drew attention to that were kind of interesting is he clearly thinks there's a big opportunity on mobile that goes beyond just having a ChatGPT app on your phone, or maybe even having a Siri on your phone. There's clearly something bigger there. He doesn't know exactly what it is, but It's going to require more inputs.

0
💬 0

4157.565 - 4161.966 David Sacks

It's that personal assistant that's seeing everything around you and helping you.

0
💬 0

4162.326 - 4172.968 Jason Calacanis

I think that's a great insight, David, because he was talking about, hey, I'm looking for a senior team member who can push back on me and understands all context. I thought that was like a very interesting to think about.

0
💬 0

4172.988 - 4190.015 David Sacks

Yeah, he's talking about an executive assistant or an assistant that has executive function as opposed to being like just an alter ego for you or what he called a sycophant. That's kind of interesting. I thought that was interesting, yeah. Yeah, and clearly he thinks there's a big opportunity in biology and scientific discovery.

0
💬 0

4190.295 - 4193.738 David Friedberg

After the break, I think we should talk about AlphaFold 3. It was just announced today. Yeah, let's do that.

0
💬 0

4193.798 - 4211.153 Jason Calacanis

And we can talk about the Apple ad in depth. I just want to also make sure people understand when people come on the pod, we don't show them questions. They don't edit the transcript. Nothing is out of bounds. If you were wondering why I didn't ask or we didn't ask about the Elon lawsuit, he's just not going to be able to comment on that. So it'd be a no comment. So, you know.

0
💬 0

4212.834 - 4217.097 David Sacks

Our time was limited and there's a lot of questions that we could ask him that would have just been a waste of time.

0
💬 0

4217.637 - 4220.219 Jason Calacanis

I just want to make sure people understand.

0
💬 0

4220.239 - 4227.284 David Sacks

Yeah, of course he's going to no comment on any lawsuit and he's already been asked about that 500 times. Should we take a quick break before we come back?

0
💬 0

4227.304 - 4247.245 Jason Calacanis

Yeah, let's take a bio break and then we'll come back with some news for you and some more banter with your favorite besties on the number one podcast in the world, the All In Podcast. All right, welcome back, everybody. Second half of the show, great guests, Sam Altman, thanks for coming on the pod. We've got a bunch of news on the docket, so let's get started.

0
💬 0

4247.665 - 4255.148 Jason Calacanis

Freyberg, you told me I could give some names of the guests that we've booked for the All In Summit. I did not. You did.

0
💬 0

4255.349 - 4264.65 David Friedberg

You've said each week, every week that I get to say some names. I did not. I appreciate your interest in the all-in summits lineup, but we do not yet have...

0
💬 0

4266.253 - 4287.367 Jason Calacanis

enough critical mass uh to feel like we should go out there well uh i am a loose cannon so i will announce my two guests and i created the summit and you took it from me so i've done a great job i will announce my guests i don't care what your opinion is i have booked two guests for the summit and it's going to be sold out look at these two guests i booked

0
💬 0

4287.927 - 4307.054 Jason Calacanis

For the third time coming back to the summit, our guy Elon Musk will be there. Hopefully in person, if not, you know, from 40,000 feet on Starlink connection, wherever he is in the world. And for the first time, our friend Mark Cuban will be coming. And so two great guests for you to look forward to. But Freeberg's got like a thousand guests coming.

0
💬 0

4307.194 - 4311.575 Jason Calacanis

He'll tell you when it's like 48 hours before the conference. But yeah, two great guests coming.

0
💬 0

4311.595 - 4317.838 David Sacks

Speaking of billionaires who are coming, isn't *** coming too? Yes, *** is coming. Yes, he's booked. So we have three billionaires.

0
💬 0

4318.218 - 4319.379 Jason Calacanis

Three billionaires, yes.

0
💬 0

4319.399 - 4319.839 David Sacks

Okay.

0
💬 0

4319.939 - 4324.542 Jason Calacanis

It hasn't fully confirmed, so don't... Okay, well, we're going to say it anyway. As penciled in. Don't say it.

0
💬 0

4324.562 - 4325.062 Chamath Palihapitiya

Don't back up.

0
💬 0

4325.082 - 4327.203 Jason Calacanis

We'll say penciled. Yeah, don't back out.

0
💬 0

4327.383 - 4330.285 Chamath Palihapitiya

This is going to be catnip for all these protest organizers.

0
💬 0

4330.305 - 4340.35 David Sacks

Like, if you ever got one place... Do not poke the bear. Well, by the way, speaking of updates, what did you guys think of the bottle for the all-in tequila? Oh, beautiful.

0
💬 0

4340.59 - 4356.456 Chamath Palihapitiya

Honestly, I will just say, I think you are doing a marvelous job. That... I was shocked at the design. Shocked meaning it is so unique and high quality. I think it's amazing. It would make me drink tequila.

0
💬 0

4358.22 - 4359.681 David Sacks

You're going to, you're going to want to.

0
💬 0

4359.741 - 4380.117 Jason Calacanis

It is stunning. Just congratulations. And yeah, it was just, when we went through the deck at the, at the monthly meeting, it was like, oh, that's nice. Oh, that's nice. We're going through the concept bottles. And then that bottle came up and everybody went like crazy. It was like somebody hitting like a Steph Curry hitting a half court shot. It was like, oh my God.

0
💬 0

4380.577 - 4389.464 Jason Calacanis

It was just so clear that you've made an iconic bottle of, that if we can produce it, oh, Lord, it is going to be a game.

0
💬 0

4389.484 - 4391.806 David Sacks

Looks like we can. Oh, is it going to make it? Yeah.

0
💬 0

4391.866 - 4395.489 Jason Calacanis

It's going to be amazing. I'm excited. I'm excited for it. You know, it's like for other things.

0
💬 0

4395.509 - 4407.439 David Sacks

I mean, the vol design is so complicated that we had to do a feasibility analysis on whether it was actually manufacturable, but it is. So, or at least the early reports are good. So, we're going to, hopefully we'll have some made for the, in time for the all-in summit.

0
💬 0

4408.283 - 4421.311 Chamath Palihapitiya

I mean, why not? I mean, it's great when we get barricaded in by all these protesters, we can drink the tequila. Did you guys see Peter Thiel? Peter Thiel got barricaded by these ding-dongs at Cambridge? My God.

0
💬 0

4421.511 - 4429.076 Jason Calacanis

Listen, people have the right to protest. I think it's great people are protesting, but surrounding people and threatening them is a little bit over the top and dangerous.

0
💬 0

4429.096 - 4430.737 David Sacks

I think you're exaggerating what happened.

0
💬 0

4431.217 - 4433.619 Jason Calacanis

Well, I don't know exactly what happened because all we see is these videos.

0
💬 0

4434.153 - 4449.125 David Sacks

Look, they're not threatening anybody, and I don't even think they tried to barricade him in. They were just outside the building, and because they were blocking the driveway, his car couldn't leave. But he wasn't physically locked in the building or something.

0
💬 0

4450.226 - 4453.308 Jason Calacanis

That's what the headlines say, but that could be fake news, fake social.

0
💬 0

4453.688 - 4460.474 Chamath Palihapitiya

This was not on my bingo card. This pro-protester support by Sachs was not on the bingo card, I got to say.

0
💬 0

4461.482 - 4485.117 David Sacks

I didn't see it coming. The Constitution of the United States in the First Amendment provides for the right of assembly, which includes protest incidents as long as they're peaceable. Now, obviously, if they go too far and they vandalize or break into buildings or use violence, then that's not peaceable. However... Expressing sentiments with which you disagree does not make it violent.

0
💬 0

4485.958 - 4506.063 David Sacks

And there's all these people out there now making the argument that if you hear something from a protester that you don't like, and you subjectively experience that as a threat to your safety, then that somehow should be treated as valid, like that's basically violent. Well, that's not what the Constitution says.

0
💬 0

4507.105 - 4528.858 David Sacks

And these people understood well just a few months ago that that was basically snowflakery. That, you know, just because somebody, you know what I'm saying? We have the rise of the woke right now where they're buying into the woke right. They're buying into this idea of safetyism, which is being exposed to ideas you don't like, to protests you don't like, is a threat to your safety. No, it's not.

0
💬 0

4529.439 - 4534.302 David Sacks

So now we have snowflakes on one side. We absolutely have snowflakery on both sides now.

0
💬 0

4534.855 - 4547.868 Jason Calacanis

It's ridiculous. The only thing I will say that I've seen is this surrounding individuals who you don't want there and locking them in a circle and then moving them out of the protest area.

0
💬 0

4547.888 - 4569.526 David Sacks

That's not cool. Yeah, obviously you can't do that. But look, I think that... Most of the protests on most of the campuses have not crossed the line. They've just occupied the lawns of these campuses. And look, I've seen some troublemakers try to barge through the encampments and claim that because they can't go through there, that somehow they're being prevented from going to class.

0
💬 0

4569.587 - 4573.689 David Sacks

Look, you just walk around the lawn and you can get to class, okay?

0
💬 0

4573.709 - 4573.789 Jason Calacanis

Yeah.

0
💬 0

4575.071 - 4585.791 David Sacks

Some of these videos are showing that these are effectively right-wing provocateurs who are engaging in left-wing tactics. I don't support it either way.

0
💬 0

4586.271 - 4600.14 Chamath Palihapitiya

By the way, some of these camps are some of the funniest things you've ever seen. It's like there are like one tent that's dedicated to like a reading room and you go in there and there's like these like... Mindfulness center? Oh my God, it's unbelievably hilarious.

0
💬 0

4600.32 - 4614.11 David Sacks

Look, there's no question that because the protests are originating on the left that there's some goofy views. Like, you know, you're dealing with like a left-wing idea complex, right? But... And, you know, it's easy to make fun of them doing different things, but...

0
💬 0

4615.09 - 4635.921 David Sacks

The fact of the matter is that most of the protests on most of these campuses are, even though they can be annoying because they're occupying part of the lawn, they're not violent. And the way they're being cracked down on, they're sending the police in at 5 a.m. to crack down on these encampments with batons and riot gear. And I find that part to be completely excessive.

0
💬 0

4636.667 - 4653.913 Jason Calacanis

Well, it's also dangerous because, you know, things can escalate when you have mobs of people and large groups of people. So I just want to make sure people understand that. Large group of people, you have a diffusion of responsibility that occurs when there's large groups of people who are passionate about things and people can get hurt. People have gotten killed at these things.

0
💬 0

4653.973 - 4662.536 Jason Calacanis

So just, you know, keep it calm, everybody. I agree with you. Like, what's the harm of these folks protesting on a lawn? It's not a big deal. When they break into buildings, of Of course.

0
💬 0

4662.576 - 4663.817 David Sacks

Yeah, that crosses the line, obviously.

0
💬 0

4663.837 - 4670.642 Jason Calacanis

Yeah, but I mean, let them sit out there and then they'll run out their food cars, their campus food cart, and they'll run out of waffles.

0
💬 0

4671.022 - 4686.212 Chamath Palihapitiya

Did you guys see the clip? I think it was on the University of Washington campus where one kid challenged this Antifa guy to a push-up contest. Oh, fantastic. I mean, it is some of the funniest stuff. Some content is coming out that's just hilarious.

0
💬 0

4686.652 - 4691.416 Jason Calacanis

My favorite was the woman who came out and said that the Columbia students needed humanitarian aid.

0
💬 0

4692.516 - 4720.689 David Sacks

oh my god the overdubs on her were hilarious i was like uh humanitarian i was like we need our door dash right now we need to be double dash some boba and we can't get it through the police we need our boba low sugar boba with the with the popping boba bubbles wasn't getting in but you know people have the right to protest and a piece of bull by the way there's a word i've never heard very good sax a piece of bull inclined to avoid argument or violent conflict very nice

0
💬 0

4721.309 - 4723.155 David Sacks

Well, it's in the Constitution. It's in the First Amendment.

0
💬 0

4723.877 - 4744.477 Jason Calacanis

Is it really? I haven't heard the word peaceable before. I mean, you and I are simpatico on this. Like, I don't... We used to have the ACLU backing up the KKK going down Main Street and really fighting for... Yeah, the Skokie decision. Yeah, they were really fighting for... And I have to say, the Overton window is opened back up. And I think it's great. All right.

0
💬 0

4744.937 - 4769.615 Jason Calacanis

We got some things on the docket here. I don't know if you guys saw the Apple new iPad ad. It's getting a bunch of criticism. They used some giant... hydraulic press to crush a bunch of creative tools, DJ turntable, trumpet, piano. People really care about Apple's ads and what they represent. We talked about that Mother Earth little vignette they created here. What do you think, Freeberg?

0
💬 0

4769.635 - 4771.077 Jason Calacanis

Did you see the ad? What was your reaction to it?

0
💬 0

4771.8 - 4774.281 David Friedberg

It made me sad. It did not make me want to buy an iPad.

0
💬 0

4776.902 - 4786.506 Chamath Palihapitiya

It made you sad? It actually elicited an emotion? Meaning like commercials? It's very rare that commercials can actually do that. Most people just zone out. Yeah, they took all this beautiful stuff and heard it.

0
💬 0

4786.846 - 4793.16 David Friedberg

It didn't feel good. I don't know. It just didn't seem like a good ad. I don't know why they did that. I don't get it. I don't know.

0
💬 0

4793.22 - 4811.329 David Sacks

I think maybe what they're trying to do is the selling point of this new iPad is that it's the thinnest one. I mean, there's no innovation left, so they're just making the devices thinner. So I think the idea was that they were going to take this hydraulic press to represent how ridiculously thin the new iPad is.

0
💬 0

4812.17 - 4829.632 David Sacks

Now, I don't know if the point there was to smush all of that good stuff into the iPad. I don't know if that's what they were trying to convey. But yeah, I think that... By destroying all those creative tools that Apple is supposed to represent, it definitely seemed very off-brand for them.

0
💬 0

4829.692 - 4841.435 David Sacks

And I think people were reacting to the fact that it was so different than what they would have done in the past. And of course, everyone was saying, well, Steve would never have done this. I do think it did land wrong.

0
💬 0

4841.495 - 4855.288 David Sacks

I mean, I didn't care that much, but I was kind of asking the question, like, why are they destroying all these creator tools that they're renowned for creating or for turning into the digital version?

0
💬 0

4856.268 - 4863.981 Jason Calacanis

Yeah. It just didn't land. I mean, Chamatha, how are you doing emotionally after seeing that? Are you okay, buddy?

0
💬 0

4864.982 - 4894.243 Chamath Palihapitiya

Yeah. I think this is... You guys see that in the Berkshire annual meeting last weekend, Tim Cook was in the audience and Buffett... was very laudatory. This is an incredible company. But he's so clever with words. He's like, you know, this is an incredible business that we will hold forever, most likely. And then it turns out that he sold $20 billion worth of Apple shares in the quarter.

0
💬 0

4894.263 - 4910.935 Chamath Palihapitiya

A caveat. Which, by the way, if you guys remember, we put that little chart up, which shows when he doesn't mention it in the annual letter, it's basically like it's foreshadowing the fact that he is just pounding the sell. And he sold $20 billion.

0
💬 0

4910.976 - 4918.097 David Sacks

Well, also holding it forever could mean one share. Yeah, exactly. We kind of need to know like how much are we talking about?

0
💬 0

4919.217 - 4926.416 Chamath Palihapitiya

I mean, it's an incredible business that has so much money with nothing to do. They're probably just going to buy back the stock. Just a total waste.

0
💬 0

4926.576 - 4937.265 Jason Calacanis

They were floating this rumor of buying Rivian, you know, after they shut down Titan Project, the internal project to make a car. It seems like a car is the only thing people can think of that would move the needle in terms of earnings.

0
💬 0

4937.425 - 4950.317 Chamath Palihapitiya

I think the problem is, J. Cal, like, you kind of become afraid of your own shadow. Meaning, the folks that are really good at M&A, like, you look at Benioff. The thing with Benioff's M&A strategy is that he's been doing it for 20 years.

0
💬 0

4950.937 - 4972.776 Chamath Palihapitiya

And so he's cut his teeth on small acquisitions and the market learns to give him trust so that when he proposes like the $27 billion Slack acquisition, he's allowed to do that. Another guy, you know, Nikesh Arora at Pan W. These last five years, people were very skeptical that he could actually roll up security because it was a super fragmented market. He's gotten permission.

0
💬 0

4973.277 - 4993.329 Chamath Palihapitiya

Then there are companies like Danaher that buy hundreds of companies. So all of these folks are examples of you start small and you earn the right to do more. Apple hasn't bought anything more than $50 or $100 million. And so the idea that all of a sudden they come out of the blue and buy a $10, $20 billion company, I think is just totally doesn't stand logic.

0
💬 0

4993.389 - 4998.132 Chamath Palihapitiya

It's just not possible for them because they'll be so afraid of their own shadow. That's the big problem. It's themselves.

0
💬 0

4999.113 - 5018.217 David Sacks

Well, if you're running out of in-house innovation and you can't do M&A, then your options are kind of limited. I mean, I do think that the fact that the big news out of Apple is the iPad's getting thinner does represent kind of the end of the road in terms of innovation. It's kind of like when they added the third camera to the iPhone.

0
💬 0

5018.897 - 5023.881 David Sacks

It reminds me of those, remember like when the Gillette Mach 3 came out and then they did the 5?

0
💬 0

5023.941 - 5025.782 Jason Calacanis

It was the best onion thing. It was like, we're doing 5. F it.

0
💬 0

5027.574 - 5035.601 David Sacks

But then Gillette actually came out with the Mach 5, so the parody became the reality. What are they going to do, add two more cameras to the iPhone? You have five cameras on it?

0
💬 0

5036.322 - 5041.606 Jason Calacanis

No, it makes no sense. And then, I don't know, anybody wants to... Remember the Apple Vision was going to change everything?

0
💬 0

5041.946 - 5044.649 Chamath Palihapitiya

Plus, why are they body-shaming the fat iPads?

0
💬 0

5046.249 - 5055.133 Jason Calacanis

It's a fair point. It's a fair point. Actually, you know what? Actually, this didn't come out yet, but it turns out the iPad is on Ozempic. It's actually dropped.

0
💬 0

5055.433 - 5057.954 David Sacks

That would have been a funnier ad. Yeah. Exactly.

0
💬 0

5058.254 - 5073.585 Jason Calacanis

Oh, oh, oh, Ozempic. We could just workshop that right here. But there was another funny one, which was making the iPhone smaller and smaller and smaller and the iPod smaller and smaller and smaller to the point it was like, you know, like a thumb size iPhone. Like the Ben Stiller phone in Zoolander.

0
💬 0

5073.645 - 5075.186 Chamath Palihapitiya

Correct.

0
💬 0

5077.568 - 5077.749 Jason Calacanis

Yeah.

0
💬 0

5078.369 - 5079.37 Chamath Palihapitiya

That was a great scene.

0
💬 0

5079.69 - 5090.79 Jason Calacanis

Is there a category that you can think of that you would love an Apple product for? There's a product in your life. that you would love to have Apple's version of it.

0
💬 0

5091.15 - 5114.186 Chamath Palihapitiya

They killed it. I think a lot of people would be very open-minded to an Apple car. They just would. It's a connected internet device, increasingly so. And they managed to flub it. They had a chance to buy Tesla. They managed to flub it. There are just too many examples here where these guys have so much money and not enough ideas. That's a shame.

0
💬 0

5115.546 - 5132.038 Jason Calacanis

It's a bummer, yeah. The one I always wanted to see them do, Zach, was... TV? The one I always wanted to see them do was the TV, and they were supposedly working on it, like the actual TV, not the little Apple TV box in the back. And that would have been extraordinary to actually have a gorgeous, you know, big television.

0
💬 0

5132.058 - 5147.358 Chamath Palihapitiya

What about a gaming console? They could have done that, you know? There's just all these things that they could have done. It's not a lack of imagination because these aren't exactly incredibly world-beating ideas. They're sitting right in front of your face. It's just the will to do it.

0
💬 0

5148.299 - 5151.083 David Sacks

Yeah. The all-in-one TV would have been good.

0
💬 0

5151.965 - 5172.753 David Friedberg

If you think back on... Apple's product lineup over the years where they've really created value is on how unique the products are. They almost create new categories. Sure, there may have been a, quote, tablet computer prior to the iPad, but the iPad really defined the tablet computer era. Sure, there was a smartphone or two before the iPhone came along, but it really defined the smartphone era.

0
💬 0

5173.513 - 5190.433 David Friedberg

And sure, there was a computer before the Apple II, and then it came along and it defined the personal computer. In all these cases, I think Apple strives to define the category. So it's very hard to define a television, if you think about it, or a gaming console in a way that you take a step up and you say, this is the new thing, this is the new platform.

0
💬 0

5191.567 - 5207.292 David Friedberg

So I don't know, that's the lens I would look at if I'm Apple in terms of like, can I redefine a car? Can I make, you know, we're all trying to fit them into an existing product bucket, but I think what they've always been so good at is identifying consumer needs and then creating an entirely new way of addressing that need in a real step change function.

0
💬 0

5208.092 - 5212.654 David Friedberg

From like the iPod, it was so different from any MP3 player ever.

0
💬 0

5212.894 - 5240.935 Chamath Palihapitiya

I think the reason why the car could have been completely re-imagined by Apple is that they have a level of credibility and trust that I think probably no other company has, and absolutely no other tech company has. And we talked about this, but I think this was the third Steve Jobs story that I left out. But in 2000, and I don't know, was it one? I launched a 99 cent download store.

0
💬 0

5241.496 - 5261.626 Chamath Palihapitiya

I think I've told you this story in Winamp. And Steve Jobs just ran total circles around us. But the reason he was able to is he had all the credibility to go to the labels and get deals done for licensing music that nobody could get done before. I think that's an example of what Apple's able to do, which is to use their political capital to change the rules.

0
💬 0

5262.286 - 5284.942 Chamath Palihapitiya

So if the thing that we would all want is safer roads and autonomous vehicles, there are regions in every town and city that could be completely converted to level five autonomous zones. If I had to pick one company that had the credibility to go and change those rules, it's them. because they could demonstrate that there was a methodical safe approach to doing something.

0
💬 0

5285.342 - 5303.245 Chamath Palihapitiya

And so the point is that even in these categories that could be totally reimagined, it's not for a lack of imagination. Again, it just goes back to a complete lack of will. And I understand because if they had, if you had $200 billion of capital on your balance sheet, I think it's probably pretty easy to get fat and lazy.

0
💬 0

5304.066 - 5311.61 Jason Calacanis

Yeah, it is. And they want to have everything built there. People don't remember, but they actually built one of the first digital cameras. You must have owned this, right, Freeberg?

0
💬 0

5312.051 - 5312.911 David Friedberg

I remember this.

0
💬 0

5313.131 - 5317.514 Jason Calacanis

Yeah, totally. It was beautiful. What did they call it? Was it the iCamera or something?

0
💬 0

5317.974 - 5318.415 David Friedberg

QuickTake.

0
💬 0

5318.855 - 5346.397 Jason Calacanis

QuickTake, yeah. The thing I would like to see Apple build, and I'm surprised they didn't, was a smart home system the way Apple has Nest. Drop cam, a door lock, you know, AV system, go after Questron or whatever, and just have your whole home automated thermostat nest. All of that would be brilliant by Apple. And right now I'm an Apple family that has all of our home automation through Google.

0
💬 0

5346.437 - 5349.199 Jason Calacanis

So it's just kind of sucks. I would like that all to be integrated.

0
💬 0

5349.219 - 5356.464 David Sacks

Actually, that would be pretty amazing. Like if they did a Crestron or Savant. Because then when you just go to your Apple TV, all your cameras just work. You don't need to.

0
💬 0

5356.504 - 5362.154 Jason Calacanis

Yes. I mean, and everybody has a home, and everybody automates their home.

0
💬 0

5362.174 - 5367.963 David Sacks

Well, everyone has Apple TV at this point, so you just make Apple TV the brain for the home system.

0
💬 0

5368.563 - 5370.326 Jason Calacanis

Right. That would be your hub.

0
💬 0

5370.366 - 5373.951 David Sacks

And you can connect your phone to it, and yes, that would be very nice.

0
💬 0

5374.472 - 5393.259 Jason Calacanis

Yeah. Like, can you imagine like the ring cameras, all that stuff being integrated? I don't know why they didn't go after that. That seems like the easy layup. Hey, you know, everybody's been talking, Friedberg, about this alpha fold, this folding proteins thing. And there's some new version out from Google.

0
💬 0

5393.759 - 5414.507 Jason Calacanis

And also, Google reportedly, we talked about this before, is also advancing talks to acquire HubSpot. So that rumor for the $30 billion market cap, HubSpot is out there as well. Freebreak, you're our resident science sultan, our resident sultan of science. And as a Google alumni, pick either story and let's go for it.

0
💬 0

5414.824 - 5435.335 David Friedberg

Yeah, I mean, I'm not sure there's much more to add on the HubSpot acquisition rumors. They are still just rumors. And I think we covered the topic a couple of weeks ago. But I will say that AlphaFold3 that was just announced today and demonstrated by Google is a real, I would say, breathtaking moment for biology, for bioengineering, for human health, for medicine.

0
💬 0

5436.229 - 5459.973 David Friedberg

And maybe I'll just take 30 seconds to kind of explain it. You remember when they introduced AlphaFold 2, we talked about DNA codes for proteins. So every three letters of DNA codes for an amino acid. So a string of DNA codes for a string of amino acids, and that's called a gene that produces a protein. And that protein is basically a long, like think about beads.

0
💬 0

5460.053 - 5478.551 David Friedberg

There's 20 different types of beads, 20 different amino acids that can be strung together. And what happens is that necklace, that bead necklace basically collapses on itself. And all those little beads stick together with each other in some complicated way that we can't deterministically model. And that creates a three-dimensional structure, which is called a protein, that molecule.

0
💬 0

5478.891 - 5495.543 David Friedberg

And that molecule does something interesting. It can break apart other molecules. It can bind molecules. It can move molecules around. So it's basically the machinery of chemistry, of biochemistry. And so proteins are what is encoded in our DNA. And then the proteins do all the work of making living organisms.

0
💬 0

5496.343 - 5511.129 David Friedberg

So Google's AlphaFold project took three-dimensional images of proteins and the DNA sequence that codes for those proteins, and then they built a predictive model that predicted the three-dimensional structure of a protein from the DNA that codes for it. And that was a huge breakthrough years ago.

0
💬 0

5511.75 - 5531.646 David Friedberg

What they just announced with AlphaFold 3 today is that they're now including all small molecules, so all the other little molecules that go into chemistry and biology that drive the function of everything we see around us, And the way that all those molecules actually bind and fit together is part of the predictive model. Why is that important?

0
💬 0

5531.746 - 5536.871 David Friedberg

Well, let's say that you're designing a new drug, and it's a protein-based drug, which biologic drugs, which most drugs are today.

0
💬 0

5537.111 - 5554.546 David Friedberg

You could find a biologic drug that binds to a cancer cell, and then you'll spend 10 years going to clinical trials, and billions of dollars later, you find out that that protein accidentally binds to other stuff and hurts other stuff in the body, and that's an off-target effect or a side effect, and that drug is pulled from the clinical trials, and it never goes to market.

0
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5555.167 - 5574.125 David Friedberg

Most drugs go through that process. They are actually tested in animals and then in humans. And we find all these side effects that arise from those drugs because we don't know how those drugs are gonna bind or interact with other things in our biochemistry. And we only discovered after we put it in. But now we can actually model that with software.

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5574.645 - 5591.501 David Friedberg

We can take that drug, we can create a three-dimensional representation of it using the software, and we can model how that drug might interact with all the other cells, all the other proteins, all the other small molecules in the body to find all the off-target effects that may arise and decide whether or not that presents a good drug candidate.

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5592.242 - 5605.854 David Friedberg

That is one example of how this capability can be used. And there are many, many others, including creating new proteins that could be used to bind molecules or stick molecules together or new proteins that could be designed to rip molecules apart.

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5606.534 - 5629.31 David Friedberg

We can now predict the function of three-dimensional molecules using this capability, which opens up all of the software-based design of chemistry, of biology, of drugs. And it really is an incredible breakthrough moment. The interesting thing that happened though is Google Alphabet has a subsidiary called Isomorphic Labs. It is a drug development subsidiary of Alphabet.

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5629.87 - 5650.742 David Friedberg

And they've basically kept all the IP for AlphaFold3 in Isomorphic. So Google is going to monetize the heck out of this capability. And what they made available was not open source code, but a web based viewer that scientists for quote, non commercial purposes can use to do some fundamental research in a web based viewer and make some experiments and try stuff out and how interactions might occur.

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5651.342 - 5668.669 David Friedberg

But no one can use it for commercial use. Only Google's isomorphic labs can. So number one, it's an incredible demonstration of what AI outside of LLMs, which we just talked about with Sam today, And obviously, we talked about other models, but LLMs being kind of this consumer text, predictive model capability.

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5668.969 - 5687.898 David Friedberg

But outside of that, there's this capability in things like chemistry, with these new AI models that can be trained and built to predict things like three dimensional chemical interactions, that is going to open up an entirely new era for human progress. And I think that's what's so exciting. I think the other side of this is Google is hugely advantaged.

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5688.258 - 5703.096 David Friedberg

And they just showed the world a little bit about some of these jewels that they have in the treasure chest. And they're like, look at what we got. We're going to make all these drugs. And they've got partnerships with all these pharma companies and isomorphic labs that they've talked about. And it's going to usher in a new era of drug development design for human health.

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5703.496 - 5718.86 David Friedberg

So all in all, I'd say it's a pretty astounding day. A lot of people are going crazy over the capability that they just demonstrated. And then it begs all this really interesting question around like, you know, what's Google going to do with it and how much value is going to be created here? So anyway, I thought it was a great story. And I just rambled on for a couple of minutes, but I don't know.

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5718.9 - 5719.421 David Friedberg

It's pretty cool.

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5719.461 - 5724.302 Jason Calacanis

Super interesting. Is this AI capable of making a science corner that David Sachs pays attention to?

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0
💬 0

5734.299 - 5742.103 Jason Calacanis

Folding Cells is the app that Saks, a casual game Saks just downloaded, is playing. How many chess moves did you make during that segment, Saks?

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5742.163 - 5761.018 David Friedberg

Sorry, let me just say one more thing. Do you guys remember we talked about Yamanaka factors and how challenging it is to basically, we can reverse aging if we can get the right proteins into cells to tune the expression of certain genes to make those cells youthful? Right now, it's a shotgun approach to trying millions of compounds and combinations of compounds to do them.

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5761.038 - 5767.619 David Friedberg

There's a lot of companies actually trying to do this right now to come up with a fountain of youth type product. We can now simulate that.

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5768.2 - 5786.346 David Friedberg

So with this system, one of the things that this AlphaFold3 can do is predict what molecules will bind and promote certain sequences of DNA, which is exactly what we try and do with the Yamanaka factor-based expression systems, and find ones that won't trigger off-target expression. So meaning we can now go through the search space and software

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5787.006 - 5805.421 David Friedberg

of creating a combination of molecules that theoretically could unlock this fountain of youth to de-age all the cells in the body and introduce an extraordinary kind of health benefit. And that's just, again, one example of the many things that are possible with this sort of platform. And I'm really, I gotta be honest, I'm really just sort of skimming the surface here of what this can do.

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5805.441 - 5812.826 David Friedberg

The capabilities and the impact are gonna be like... I know I say this sort of stuff a lot, but it's going to be pretty profound.

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5813.226 - 5833.561 Chamath Palihapitiya

On the blog post, they have this incredible video that they show of the coronavirus that creates a common cold, I think the 7-PNM protein. And not only did they literally predict it accurately, they also predicted how it interacts with an antibody, with a sugar. It's nuts.

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5833.661 - 5840.205 Chamath Palihapitiya

So you could see a world where like, I don't know, you just get a vaccine for the cold and it's kind of like you never have colds again.

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5841.346 - 5850.211 David Friedberg

I mean, simple stuff, but so powerful. And you can filter out stuff that has off-target effects. So, so much of drug discovery and all the side effects stuff can start to be solved for in silico.

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5850.931 - 5870.518 David Friedberg

And you could think about running extraordinarily large, use a model like this, run extraordinarily large simulations in a search space of chemistry to find stuff that does things in the body that can unlock all these benefits, can do all sorts of amazing things to destroy cancer, to destroy viruses, to repair cells, to de-age cells.

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5871.127 - 5873.788 Jason Calacanis

And this is a hundred billion dollar business. They say, Oh my God.

0
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5873.808 - 5882.971 David Friedberg

I mean, this alone, I feel like this is where I, I've said this before. I think Google's got this like portfolio of like quiet. Yeah. Yeah.

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5882.991 - 5884.711 Jason Calacanis

What if they hit?

0
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5884.871 - 5890.153 David Friedberg

And the fact, and I think the fact that they didn't open source everything in this says a lot about their intentions. Yeah.

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5890.353 - 5903.743 Jason Calacanis

Yeah, open source when you're behind, closed source, lock it up when you're ahead. The Yamanaka, actually, interestingly, Yamanaka is the Japanese whiskey that Saks serves on his plane as well. It's delicious. I love that Hokkaido, Yakanama.

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5904.163 - 5910.367 David Friedberg

Jason, I feel like if you didn't find your way to Silicon Valley, you could be like a Vegas lounge comedy guy. Absolutely.

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💬 0

5910.467 - 5910.988 Jason Calacanis

For sure.

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5911.128 - 5911.308 David Friedberg

Yeah.

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5911.508 - 5912.289 Jason Calacanis

I was actually, yeah.

0
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5912.329 - 5918.594 David Friedberg

Somebody said I should do like those 1950s, those 1950s talk shows where the guys would do like the, the stage show. Yeah.

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5918.614 - 5937.929 Jason Calacanis

Somebody told me I should do, um, like Spalding gray, Eric Boghossian style stuff. I don't know if you guys remember like the, uh, the monologue is from the eighties in New York. It's like, Oh, that's interesting. Maybe. All right, everybody. Thanks for tuning in to the world's number one podcast. Can you believe we did it? Uh, the number one podcast in the world. And yeah,

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5938.31 - 5960.254 Jason Calacanis

The All In Summit, the TED killer. If you are going to TED, congratulations for genuflecting. If you want to talk about real issues, come to the All In Summit. And if you are protesting at the all-in summit, let us know what mock meat you would like to have. Freeburg is setting up mock meat stations for all of our protesters. And what milk you would like. Yeah, all vegan.

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5960.274 - 5961.615 Jason Calacanis

If you want, if you're oat milk, soy nut milk.

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💬 0

5961.655 - 5962.836 Chamath Palihapitiya

And your preference of nut milk.

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💬 0

5962.856 - 5963.977 Jason Calacanis

Just please, when you come to protest.

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💬 0

5963.997 - 5967.019 David Friedberg

We have five different kinds of xanthan gum you can choose from, right, Jamal?

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5967.039 - 5971.322 Jason Calacanis

We have all of the nut milks you could want. And then there'll be mindful yoga with guns.

0
💬 0

5971.402 - 5973.003 Chamath Palihapitiya

Can we have some soy-like to them, please?

0
💬 0

5973.103 - 5980.39 Jason Calacanis

Yes. On the south lawn, we'll have the goat yoga going on. So, just please note that. The goat yoga will be going on for all of you.

0
💬 0

5980.51 - 5986.756 Jason Calacanis

It's very thoughtful for you to make sure that our protesters are going to be well fed, well taken care of.

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5986.816 - 6002.028 Jason Calacanis

Yes. We're actually – Freiburg is working on the protester gift bags. The protester gift bags. They're made of Yakima-folded proteins. So, you're good. Yeah. Folding projects. I think I saw them opening for the Smashing Pumpkins in 2003. On fire.

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6004.529 - 6006.59 David Sacks

Enough. I'll be here for three more nights.

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6006.85 - 6013.392 David Sacks

Love you, boys. Bye-bye. Love you, besties. Is this the all-on pod or open mic night? What's going on? It's basically it. I'm just bored.

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6023.991 - 6027.805 David Friedberg

Open source it to the fans and they've just gone crazy with it. Love you, Wes. Nice.

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💬 0

6056.33 - 6057.737 Jason Calacanis

We need to get merch.

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6070.945 - 6095.96 Jason Calacanis

That's episode 178. And now the plugs. The All In Summit is taking place in Los Angeles on September 8th through the 10th. You can apply for a ticket at summit.allinpodcast.co. Scholarships will be coming soon. If you want to see the four of us interview Sam Altman, you can actually see the video of this podcast on YouTube, youtube.com slash at all in or just search All In Podcast.

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6096.5 - 6120.618 Jason Calacanis

and hit the alert bell and you'll get updates when we post. We're doing a Q&A episode live when the YouTube channel hits 500,000. And we're going to do a party in Vegas, my understanding, when we hit a million subscribers. So look for that as well. You can follow us on X, x.com slash the all in pod. TikTok is all underscore in underscore talk. Instagram, the all in pod.

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💬 0

6121.318 - 6141.354 Jason Calacanis

And on LinkedIn, just search for the All In Podcast. You can follow Chamath at x.com slash Chamath. And you can sign up for a Substack at chamath.substack.com. I do. Freeberg can be followed at x.com slash Freeberg. And Ohalo is hiring. Click on the careers page at ohalogenetics.com. And you can follow Sachs at x.com slash David Sachs.

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6141.614 - 6161.459 Jason Calacanis

Sachs recently spoke at the American Moment Conference and people are going crazy for it. It's pinned to his tweet on his ex-profile. I'm Jason Calacanis. I am x.com slash Jason. And if you want to see pictures of my bulldogs and the food I'm eating, go to instagram.com slash Jason in the first name club. You can listen to my other podcasts this week in startups.

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6161.499 - 6182.289 Jason Calacanis

Just search for it on YouTube or your favorite podcast player. We are hiring a researcher. Apply to be a researcher doing primary research and working with me and producer Nick, working in data and science and being able to do great research, finance, et cetera. allinpodcast.co slash research. It's a full-time job working with us, the besties. We'll see you all next time on the All In Podcast.

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