#358 ‒ Peter’s takeaways on navigating HRT, rejuvenating the face, understanding the biology of aging, optimizing fertility, and learning to live well from the dying | Quarterly Podcast Summary #6
28 Jul 2025
Contributed by Lukas
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#357 ‒ A new era of longevity science: models of aging, human trials of rapamycin, biological clocks, promising compounds, and lifestyle interventions | Brian Kennedy, Ph.D.
21 Jul 2025
Contributed by Lukas
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#356 - AMA #73: Preserving brain health, optimizing exercise programming, improving body composition, and more
14 Jul 2025
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Navigating bone health: early life influences and advanced strategies for improvement and injury prevention (#214 rebroadcast)
Mon, 07 Jul
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#355 – Skincare strategies, the science of facial aging, and cosmetic-intervention guidance | Tanuj Nakra, M.D. & Suzan Obagi, M.D.
Mon, 30 Jun
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#354 – What the dying can teach us about living well: lessons on life and reflections on mortality | BJ Miller, M.D. and Bridget Sumser, L.C.S.W.
Mon, 23 Jun
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#353 - AMA #72: Fasting: benefits for body composition and disease prevention, potential risks, and Peter’s updated practical framework
Mon, 16 Jun
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#352 ‒ Female fertility: optimizing reproductive health, diagnosing and treating infertility and PCOS, and understanding the IVF process | Paula Amato, M.D.
Mon, 09 Jun
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#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.
Mon, 02 Jun
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#350 ‒ Injury prevention, recovery, and performance optimization for every decade | Kyler Brown, D.C.
Mon, 26 May
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#349 - AMA #71: Building strength and muscle mass: how to optimize training, nutrition, and more for longevity
Mon, 19 May
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#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.
Mon, 12 May
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#347 – Peter’s takeaways on mastering sleep, dealing with chronic pain, developing breakthrough cancer drugs, transforming healthcare with AI, advancing radiation therapy, and healing trauma | Quarterly Podcast Summary #5
Mon, 05 May
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#346 - Scaling biotech and improving global health: lessons from an extraordinary career in medicine | Susan Desmond-Hellmann, M.D., M.P.H.
Mon, 28 Apr
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#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.
Mon, 21 Apr
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#344 - AMA #70: Nicotine: impact on cognitive function, performance, and mood, health risks, delivery modalities, and smoking cessation strategies
Mon, 14 Apr
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#343 – The evolving role of radiation: advancements in cancer treatment, emerging low-dose treatments for arthritis, tendonitis, and injuries, and addressing misconceptions | Sanjay Mehta, M.D.
Mon, 07 Apr
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#342 ‒ Aging well: Peter shares strategies for improving longevity with residents at a senior living center
Mon, 31 Mar
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#341 - Overcoming insomnia: improving sleep hygiene and treating disordered sleep with cognitive behavioral therapy for insomnia | Ashley Mason, Ph.D.
Mon, 24 Mar
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#340 - AMA #69: Scrutinizing supplements: creatine, fish oil, vitamin D, and more—a framework for understanding effectiveness, quality, and individual need
Mon, 17 Mar
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#339 - Unpacking trauma: How early wounds shape behavior and the path toward healing | Jeff English
Mon, 10 Mar
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#338 ‒ Peter’s takeaways on aerobic exercise and VO2 max, insulin resistance, rising healthcare costs, treating children with autism and ADHD, and strength training | Quarterly Podcast Summary #4
Mon, 03 Mar
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#337 - Insulin resistance masterclass: The full body impact of metabolic dysfunction and prevention, diagnosis, and treatment | Ralph DeFronzo, M.D.
Mon, 24 Feb
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#336 - AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more
Mon, 17 Feb
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#335 ‒ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.
Mon, 10 Feb
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#334 - Cardiovascular disease, the number one killer: development, biomarkers, apoB, cholesterol, brain health, and more | Tom Dayspring, M.D.
Mon, 03 Feb
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#333 ‒ Longevity roundtable — the science of aging, geroprotective molecules, lifestyle interventions, challenges in research, and more | Steven Austad, Matt Kaeberlein, Richard Miller
Mon, 27 Jan
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#332 - AMA #67: Microplastics, PFAS, and phthalates: understanding health risks and a framework for minimizing exposure and mitigating risk
Mon, 20 Jan
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#331 ‒ Optimizing endurance performance: metrics, nutrition, lactate, and more insights from elite performers | Olav Aleksander Bu (Pt. 2)
Mon, 13 Jan
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#330 – Autism, ADHD, and Anxiety: Understanding the rise in autism and a multidisciplinary approach to diagnosis and treatment of each condition in children | Trenna Sutcliffe, M.D.
Mon, 06 Jan
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Building & Changing Habits | James Clear (#183 rebroadcast)
Mon, 30 Dec
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#329 ‒ Special AMA: Peter on exercise, important labs, building good habits, promising longevity research, and more
Mon, 16 Dec
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#328 - AMA #66: Optimizing nutrition for health and longevity: myth of a “best” diet, complexities of nutrition science, and practical steps for building a sustainable diet
Mon, 09 Dec
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#327 - Choices, costs, and challenges in US healthcare: insurance intricacies, drug pricing, economic impacts, and potential reforms | Saum Sutaria, M.D.
Mon, 02 Dec
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Optimizing life for maximum fulfillment | Bill Perkins (#237 rebroadcast)
Mon, 25 Nov
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#326 - AMA #65: Red light therapy: promising applications, mixed evidence, and impact on health and aging
Mon, 18 Nov
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#325 ‒ Peter’s key takeaways on bone health, calorie restriction and energy balance, dopamine and addiction, gene editing, and testosterone therapy safety with a prostate cancer diagnosis | Quarterly Podcast Summary #3
Mon, 11 Nov
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#324 ‒ Metabolism, energy balance, and aging: How diet, calorie restriction, and macronutrients influence longevity and metabolic health | Eric Ravussin, Ph.D.
Mon, 04 Nov
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#323 - CRISPR and the future of gene editing: scientific advances, genetic therapies, disease treatment potential, and ethical considerations | Feng Zhang, Ph.D.
Mon, 28 Oct
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#322 - Bone health for life: building strong bones, preventing age-related loss, and reversing osteoporosis with evidence-based exercise | Belinda Beck, Ph.D.
Mon, 21 Oct
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#321 – Dopamine and addiction: navigating pleasure, pain, and the path to recovery | Anna Lembke, M.D.
Mon, 14 Oct
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#320 – AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) - efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape
Mon, 07 Oct
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#319 ‒ Peter's key takeaways on liver health, heart rate variability, AI in medicine, klotho, and lactate metabolism | Quarterly Podcast Summary #2
Mon, 30 Sep
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#318 ‒ Cycling phenom and Tour de France champion Tadej Pogačar reveals his training strategies, on-bike nutrition, and future aspirations
Mon, 23 Sep
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#317 ‒ Reforming medicine: uncovering blind spots, challenging the norm, and embracing innovation | Marty Makary, M.D., M.P.H.
Mon, 16 Sep
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#316 - AMA #63: A guide for hair loss: causes, treatments, transplants, and sex-specific considerations
Mon, 09 Sep
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Improve your decision-making, frameworks for learning, backcasting, and more | Annie Duke (#60 rebroadcast)
Mon, 02 Sep
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#315 ‒ Life after near-death: a new perspective on living, dying, and the afterlife | Sebastian Junger
Mon, 26 Aug
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#314 ‒ Rethinking nutrition science: the evolving landscape of obesity treatment, GLP-1 agonists, protein, and the need for higher research standards | David Allison, Ph.D.
Mon, 19 Aug
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#313 - AMA #62: Protein’s impact on appetite and weight management, and uric acid's link to disease and how to manage levels
Mon, 12 Aug
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#312 - A masterclass in lactate: Its critical role as metabolic fuel, implications for diseases, and therapeutic potential from cancer to brain health and beyond | George A. Brooks, Ph.D.
Mon, 05 Aug
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#311 ‒ Longevity 101: a foundational guide to Peter's frameworks for longevity, and understanding CVD, cancer, neurodegenerative disease, nutrition, exercise, sleep, and more
Mon, 29 Jul
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#310 - The relationship between testosterone and prostate cancer, testosterone replacement therapy, and tools for predicting cancer aggressiveness and guiding therapy | Ted Schaeffer, M.D., Ph.D.
Mon, 22 Jul
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#309 ‒ AI in medicine: its potential to revolutionize disease prediction, diagnosis, and outcomes, causes for concern in medicine and beyond, and more | Isaac Kohane, M.D., Ph.D.
Mon, 15 Jul
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Zone 2 training: impact on longevity and mitochondrial function, how to dose frequency and duration, and more | Iñigo San-Millán, Ph.D. (#201 rebroadcast)
Mon, 08 Jul
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#308 - AMA #61: Sun exposure, sunscreen, and skin health: relationship between sun exposure and skin cancer, vitamin D production, and photoaging, how to choose a sunscreen, and more
Mon, 01 Jul
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#307 ‒ Exercise for aging people: where to begin, and how to minimize risk while maximizing potential | Peter Attia, M.D.
Mon, 24 Jun
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#306 - AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more
Mon, 17 Jun
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#305 ‒ Heart rate variability: how to measure, interpret, and utilize HRV for training and health optimization | Joel Jamieson
Mon, 10 Jun
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#304 – NEW: Introducing quarterly podcast summaries - Peter shares his biggest takeaways on muscle protein synthesis, VO2 max, toe strength, gut health, and more
Mon, 03 Jun
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#303 - A breakthrough in Alzheimer’s disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer's disease | Dena Dubal, M.D., Ph.D.
Mon, 27 May
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#302 - Confronting a metabolic epidemic: understanding liver health and how to prevent, diagnose, and manage liver disease | Julia Wattacheril, M.D., M.P.H.
Mon, 20 May
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#301 - AMA #59: Inflammation: its impact on aging and disease risk, and how to identify, prevent, and reduce it
Mon, 13 May
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#300 - Special episode: Peter on exercise, fasting, nutrition, stem cells, geroprotective drugs, and more — promising interventions or just noise?
Mon, 06 May
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Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna’s death
Mon, 29 Apr
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#299 ‒ Optimizing muscle protein synthesis: the crucial impact of protein quality and quantity, and the key role of resistance training | Luc van Loon, Ph.D.
Mon, 22 Apr
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#298 ‒ The impact of emotional health on longevity, self-audit strategies, improving well-being, and more | Paul Conti, M.D.
Mon, 15 Apr
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#297 - AMA #58: Iron: its role in health, testing methods, and strategies for preventing and managing iron deficiency
Mon, 08 Apr
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#296 ‒ Foot health: preventing and treating common injuries, enhancing strength and mobility, picking footwear, and more | Courtney Conley, D.C.
Mon, 01 Apr
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#295 ‒ Roadway death and injury: why everyone should care and what you can do to reduce risk | Mark Rosekind, Ph.D.
Mon, 25 Mar
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#294 ‒ Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth | Olav Aleksander Bu
Mon, 18 Mar
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#293 - AMA #57: High-intensity interval training: benefits, risks, protocols, and impact on longevity
Mon, 11 Mar
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#292 ‒ Rucking: benefits, gear, FAQs, and the journey from Special Forces to founding GORUCK | Jason McCarthy
Mon, 04 Mar
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#291 ‒ The role of testosterone in males and females, performance-enhancing drugs, sustainable fat loss, supplements, and more | Derek, More Plates More Dates Pt.2
Mon, 26 Feb
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#290 ‒ Liquid biopsies for early cancer detection, the role of epigenetics in aging, and the future of aging research | Alex Aravanis, M.D., Ph.D.
Mon, 19 Feb
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#289 - AMA #56: Cancer screening: pros and cons, screening options, interpreting results, and more
Mon, 12 Feb
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#288 ‒ The impact of gratitude, serving others, embracing mortality, and living intentionally | Walter Green
Mon, 05 Feb
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#287 ‒ Lower back pain: causes, treatment, and prevention of lower back injuries and pain | Stuart McGill, Ph.D.
Mon, 29 Jan
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#286 ‒ Journal club with Andrew Huberman: the impact of light exposure on mental health and an immunotherapy breakthrough for cancer treatment
Mon, 22 Jan
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#285 - AMA #55: Exercise: longevity-focused training, goal setting, improving deficiencies, managing emotional stress, and more
Mon, 15 Jan
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#284 ‒ Overcoming addictive behaviors, elevating wellbeing, thriving in an era of excess, and the scarcity loop | Michael Easter, M.A.
Mon, 08 Jan
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James Clear: Building & Changing Habits (#183 rebroadcast)
Mon, 01 Jan
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#283 ‒ Gut health & the microbiome: improving and maintaining the microbiome, probiotics, prebiotics, innovative treatments, and more | Colleen Cutcliffe, Ph.D.
Mon, 18 Dec
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#282 - AMA #54: Magnesium: risks of deficiency, how to correct it, supplement options, potential cognitive and sleep benefits, and more
Mon, 11 Dec
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#281 ‒ Longevity drugs, aging biomarkers, and updated findings from the Interventions Testing Program (ITP) | Rich Miller, M.D., Ph.D.
Mon, 04 Dec
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#280 ‒ Cultivating happiness, emotional self-management, and more | Arthur Brooks Ph.D.
Mon, 27 Nov
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The world’s most important doctor to millions in the war-torn and remote villages of Sudan | Tom Catena, M.D. (#40 rebroadcast)
Mon, 20 Nov
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#279 - AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and the impact of statins
Mon, 13 Nov
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#278 ‒ Breast cancer: how to catch, treat, and survive breast cancer | Harold Burstein, M.D., Ph.D.
Mon, 06 Nov
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#277 ‒ Food allergies: causes, prevention, and treatment with immunotherapy | Kari Nadeau, M.D., Ph.D.
Mon, 30 Oct
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#276 ‒ Special episode: Peter answers questions on longevity, supplements, protein, fasting, apoB, statins, and more
Mon, 23 Oct
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#275 - AMA #52: Hormone replacement therapy: practical applications and the role of compounding pharmacies
Mon, 16 Oct
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#274 - Performance-enhancing drugs and hormones: risks, rewards, and broader implications for the public | Derek: More Plates, More Dates
Mon, 09 Oct
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#273 ‒ Prostate health: common problems, cancer prevention, screening, treatment, and more | Ted Schaeffer, M.D., Ph.D.
Mon, 02 Oct
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#272 ‒ Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more | David Sabatini, M.D., Ph.D. and Matt Kaeberlein, Ph.D.
Mon, 25 Sep
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#271 - AMA #51: Understanding and improving your metabolic health
Mon, 18 Sep
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#270 ‒ Journal club with Andrew Huberman: metformin as a geroprotective drug, the power of belief, and how to read scientific papers
Mon, 11 Sep
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#269 - Good vs. bad science: how to read and understand scientific studies
Mon, 04 Sep
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#268 ‒ Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D.
Mon, 28 Aug
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#267 ‒ The latest in cancer therapeutics, diagnostics, and early detection | Keith Flaherty, M.D.
Mon, 21 Aug
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