Habits and Hustle
Episode 453: Dave Asprey: Biohacking Secrets - Testosterone, Peptides, and Daily Routines for Optimal Human Performance
Tue, 27 May 2025
Today, I’m back for part 2 of my conversation with Dave Asprey. In this episode, we get into the controversial health practices and daily routines that have transformed his health and energy. Dave reveals his complete daily protocol, including cold plunges, infrared saunas, and the shocking revelation that he takes 150 supplements daily. He challenges conventional wisdom about exercise ("it doesn't make you lose weight"), nutrition ("vegan diets were my biggest mistake"), and controversial testosterone optimization protocols that he's followed since age 26. Dave Asprey is the founder of nine companies, including Bulletproof, Danger Coffee, TrueDark, and Upgrade Labs. He's authored bestselling books including "The Bulletproof Diet," "Head Strong," and his newest release, "Heavily Meditated." Dave is credited with creating three unique billion-dollar markets: MCT Oil, Collagen Protein, and Functional Coffee. What We Discuss: needs updated when audio is done (01:08) Facing Trauma as an Entrepreneur (09:30) Identifying and Managing Toxic Personalities (19:46) Sleep, Biohacking, and Longevity Insights (29:43) Retraining the Brain for Neurotypical Function (35:20) Alzheimer's and Cognitive Enhancement Solutions (46:01) Debating Vaccines and Health Choices (55:41) Optimizing Longevity With Biohacking Supplements …and more! Thank you to our sponsors: Therasage: Head over to therasage.com and use code Be Bold for 15% off TruNiagen: Head over to truniagen.com and use code HUSTLE20 to get $20 off any purchase over $100. Magic Mind: Head over to www.magicmind.com/jen and use code Jen at checkout. Air Doctor: Go to airdoctorpro.com and use promo code HUSTLE for up to $300 off and a 3-year warranty on air purifiers. Bio.me: Link to daily prebiotic fiber here, code Jennifer20 for 20% off. Momentous: Shop this link and use code Jen for 20% off David: Buy 4, get the 5th free at davidprotein.com/habitsandhustle. Find more from Jen: Website: https://www.jennifercohen.com/ Instagram: @therealjencohen Books: https://www.jennifercohen.com/books Speaking: https://www.jennifercohen.com/speaking-engagement Find more from Dave Aspry: Website: https://daveasprey.com/ X: https://www.instagram.com/dave.asprey/?hl=en YouTube: https://www.youtube.com/c/DaveAspreyBPR
Chapter 1: What are Dave Asprey's daily biohacking routines?
I usually wear it this way because then if you need to breathe through the side of your mouth, you can. You just want to make it so that when you're asleep, your mouth is held close. And the difference in outcomes for sleep and brain health, it's profound.
Chapter 2: How does Dave manage sleep and circadian biology?
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Trust me, you'll be happy you did. Give me a few more nights. I want to know like all the habits.
my bed is electrically grounded, so I drop the static charge that builds up during the day. I wear the true dark glasses for sleep about an hour before bed or when I'm home, my entire house has dim red lighting that I turn on at night. So it looks like a submarine or a house of ill repute. Really? This is the coolest thing. My girlfriend didn't do any of this stuff.
And we walked through LAX two nights ago because we landed at 10 o'clock. And she was wearing her true dark glasses too. And I didn't make her do it. She's like, can I do that? Because you feel so much better when you have darkness at night. It's unbelievable. So yeah, I go to a hotel room, I turn off a little red light and I turn off all the bright lights and I turn on my red light.
And then I have an environment where my body knows it's nighttime, so I should go to sleep. So light's important. Electrical grounding is important. I do a handful of stuff like supplements before I go to sleep.
What supplements are you taking at night?
I take like 40 of them.
At night?
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Chapter 3: What supplements does Dave take for optimal health?
I love it. Okay. When you have autism like that, there's two things going on. One, your mitochondria don't make enough energy. And two, your nerves, your sensory input, they have static on them. So when you're a little baby, you're trying to make sense of the world. Like, is that light important or not important? Is that vibration and that sound important or not important?
and you're like a little large language model trying to figure out what's good, what's not. But when you don't have enough power for your central processor, which is the mitochondrial problem, and there's static on everything, the brain becomes hyper-efficient,
but it ignores a huge amount of the data because it can't sort it out from the chaos from all the static so there's static in your eyes i didn't have peripheral vision i did not know how to see peripherally until i was in my 30s and i worked with a developmental ophthalmologist and i just did an episode with bryce applebaum on vision training and i learned how to see in my peripheral vision because my brain's like i don't need that data to live so i was seeing in tunnel vision and i didn't know it
My left eye was turned off half the time because it was too much work for my brain to make him go. The brain will make these incredible sacrifices on your perception of the world just to make sure it can function.
You turned your eye back on? Yeah. I could sit with you for three weeks and have more questions. I'm so sorry.
It's okay. Here's the basis, though. If you can turn the power back on, which is fixing your mitochondria, which is fundamental to the whole bioactive movement, all of a sudden, wow, now I have a hyper-efficient software code and my operating system is meant for low power, but I have tons of power. So now I can really do things that really would be hard to do otherwise.
Problem is I don't have a good signal. So then you have to teach the brain how to clean the visual signal, how to clean the auditory signal. And that had to do with figuring out where the little gaps in my hearing was where it didn't match, and then doing uncomfortable hearing exercises that trained my brain to fill in the gaps in my hearing.
And then the tongue, my tongue was glued to the floor of my mouth. I had to have the surgery for that and do a bunch of tongue rehab, which affects your fascia and your whole movement. And I had to, like I said, spread out my palate and move my jaw forward so my nervous system would work.
And then I had to learn how to crawl because I never learned how to crawl as a kid because I was reading in 18 months. Like this stuff, most people are never going to do this. But if you want to, you can take a brain that is not neurotypical and you can maintain the gift of And you can recover from the downside.
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