Dr. Peter Attia

I was like, they're just as thick. So I buy one of those. And every time I encounter the word meiosis and mitosis, I assume it's a spelling mistake because I bought the knockoff book. So I'm treating it as the same thing. Every time I see the word meiosis, I'm like, these guys, they just misspelled it, idiots. It's mitosis, mitosis, mitosis.

I was like, they're just as thick. So I buy one of those. And every time I encounter the word meiosis and mitosis, I assume it's a spelling mistake because I bought the knockoff book. So I'm treating it as the same thing. Every time I see the word meiosis, I'm like, these guys, they just misspelled it, idiots. It's mitosis, mitosis, mitosis.

Finally, on the night before the exam, which I still remember, August 17th was the day I took the test. I realized they were two totally different things. Big things. Oh my God. That realization might've got me into med school because I think I barely got a 10 on the biology section, which was, it's hard to get into a good med school if you get below that.

Finally, on the night before the exam, which I still remember, August 17th was the day I took the test. I realized they were two totally different things. Big things. Oh my God. That realization might've got me into med school because I think I barely got a 10 on the biology section, which was, it's hard to get into a good med school if you get below that.

So anyway, to this day, I get such a chuckle out of The confusion of the nomenclature. But again, just to explain for people, mitosis is what happens when cells are dividing in our body constantly where they're trying to create a perfect replica of the entire suite of DNA. So really, to my knowledge, the only time we're undergoing meiosis is in the creation of an egg or a sperm. That's right.

So anyway, to this day, I get such a chuckle out of The confusion of the nomenclature. But again, just to explain for people, mitosis is what happens when cells are dividing in our body constantly where they're trying to create a perfect replica of the entire suite of DNA. So really, to my knowledge, the only time we're undergoing meiosis is in the creation of an egg or a sperm. That's right.

Okay. Now, remind me, are women born with all of their eggs? I feel like that's something I vaguely remember.

Okay. Now, remind me, are women born with all of their eggs? I feel like that's something I vaguely remember.

But sperm are constantly renewed. Is that just a mass space problem? Because the testes, if we did the same thing women did, would we just have to have an enormous set of testes? Why do you think out of the box like that? No, I'm not sure. I mean...

But sperm are constantly renewed. Is that just a mass space problem? Because the testes, if we did the same thing women did, would we just have to have an enormous set of testes? Why do you think out of the box like that? No, I'm not sure. I mean...

That's an interesting point. So it's transgenerational. Does that mean that the father is more likely to pass on environmental stressors than the mother? Probably, yeah. And that's definitely been shown. Okay, so let's go back to it. So the sperm is the actual cell. Where does it get the little tail from and what is the other part of the cocktail that is...

That's an interesting point. So it's transgenerational. Does that mean that the father is more likely to pass on environmental stressors than the mother? Probably, yeah. And that's definitely been shown. Okay, so let's go back to it. So the sperm is the actual cell. Where does it get the little tail from and what is the other part of the cocktail that is...

Is there any other cell in the body that is capable of that?

Is there any other cell in the body that is capable of that?

And a man potentially has access to this cell his entire life? Yep. As long as he's making sperm.

And a man potentially has access to this cell his entire life? Yep. As long as he's making sperm.

Actually, let's focus on that for a second. I hadn't considered that. So when the cell that is becoming a sperm undergoes meiosis and it divides, what's the fraction of times when this becomes an aneuploidic sperm? And explain maybe to people what aneuploidy is and what's the process by which that thing gets discarded?

Actually, let's focus on that for a second. I hadn't considered that. So when the cell that is becoming a sperm undergoes meiosis and it divides, what's the fraction of times when this becomes an aneuploidic sperm? And explain maybe to people what aneuploidy is and what's the process by which that thing gets discarded?

So something is getting filtered. So there's a filter. Yeah, and just so folks know, when we say aneuploidy, we mean you don't have one copy of each chromosome. You either have none or you have two or anything that's not one is bad. Right. When aneuploidy occurs in the fusion of the sperm and the egg, do we know, I guess we can figure out pretty easily if it's maternal or paternal in origin?

So something is getting filtered. So there's a filter. Yeah, and just so folks know, when we say aneuploidy, we mean you don't have one copy of each chromosome. You either have none or you have two or anything that's not one is bad. Right. When aneuploidy occurs in the fusion of the sperm and the egg, do we know, I guess we can figure out pretty easily if it's maternal or paternal in origin?