Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Pricing

Dr. Peter Attia

👤 Person
11178 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

But I was trying to think about the best way to start this. The first thing that came to my mind was, can we just explain what's involved in conception? and maybe do it through the lens of the sperm, but how much of a challenge is this? I mean, obviously there's an enormous evolutionary pressure for this to go as easily as possible, but what is actually involved?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

But I was trying to think about the best way to start this. The first thing that came to my mind was, can we just explain what's involved in conception? and maybe do it through the lens of the sperm, but how much of a challenge is this? I mean, obviously there's an enormous evolutionary pressure for this to go as easily as possible, but what is actually involved?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So what happens for a sperm to fuse with an egg? What are all the things that are standing in its way, so to speak?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So what happens for a sperm to fuse with an egg? What are all the things that are standing in its way, so to speak?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

By the way, is there an evolutionary explanation for that phenomenon?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

By the way, is there an evolutionary explanation for that phenomenon?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And typically absorbs the immune system, secretes FCR receptor. And by the way, we've referred to the immune system a couple of times now. What is it? Is it just a bunch of antibodies? Are they B cells? What is the barrier? There's T cells, B cells, and antibodies. It's a full immune response. Absolutely. So it's a specific immune response. Anything for it.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And typically absorbs the immune system, secretes FCR receptor. And by the way, we've referred to the immune system a couple of times now. What is it? Is it just a bunch of antibodies? Are they B cells? What is the barrier? There's T cells, B cells, and antibodies. It's a full immune response. Absolutely. So it's a specific immune response. Anything for it.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

If you're not able to deactivate the system, you're not going to be able to get through because the immune system is active. Let's go through those numbers one more time. About 100 million ejaculated. At the cervix. 5 million get through. To cervix, into the uterus.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

If you're not able to deactivate the system, you're not going to be able to get through because the immune system is active. Let's go through those numbers one more time. About 100 million ejaculated. At the cervix. 5 million get through. To cervix, into the uterus.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So let's also define what makes up the ejaculate because we've talked about the sperm. So how are sperm made? Because an important consideration for a sperm is it can only have half the genetic information contained within all the other cells in the man's body. So when does that take place? So the testicle makes sperm.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So let's also define what makes up the ejaculate because we've talked about the sperm. So how are sperm made? Because an important consideration for a sperm is it can only have half the genetic information contained within all the other cells in the man's body. So when does that take place? So the testicle makes sperm.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

But it's not always the same half.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

But it's not always the same half.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

It's not the same as when it started. Yeah. A funny story, which I think I've shared on the podcast before, but if not, I'm sure someone will be amused by my stupidity.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

It's not the same as when it started. Yeah. A funny story, which I think I've shared on the podcast before, but if not, I'm sure someone will be amused by my stupidity.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

I had to take the MCAT before doing any of the pre-med stuff because I had studied engineering and then decided I wanted to do medicine, but didn't want to spend two years preparing, one year taking the post back and then the MCAT and then doing it. So I was like, I'm going to just wing it and take this MCAT having never taken a biology class since high school. I took freshman biology.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

I had to take the MCAT before doing any of the pre-med stuff because I had studied engineering and then decided I wanted to do medicine, but didn't want to spend two years preparing, one year taking the post back and then the MCAT and then doing it. So I was like, I'm going to just wing it and take this MCAT having never taken a biology class since high school. I took freshman biology.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So I am studying my heart out for this little MCAT test and the physics and the chemistry are fine. But this biology thing is killing me. And I bought this cheap study guide. I didn't have the money or I didn't want to splurge for the official study guide. There's an official MCAT study guide. But the thing was like 60 bucks. But there were these knockoff books for 10 bucks.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So I am studying my heart out for this little MCAT test and the physics and the chemistry are fine. But this biology thing is killing me. And I bought this cheap study guide. I didn't have the money or I didn't want to splurge for the official study guide. There's an official MCAT study guide. But the thing was like 60 bucks. But there were these knockoff books for 10 bucks.