Dr. Peter Attia

If you look at the embryo, it's kind of hard to tell.

If you look at the embryo, it's kind of hard to tell.

So this is a man who's XXY instead of XY. So 47 chromosomes, not 46. Yep. And phenotypically, he kind of has a distinctive look, right? 10% of the time. Oh, really? 90% of the time, a man with Klinefelter's, you'd never know. Yeah.

So this is a man who's XXY instead of XY. So 47 chromosomes, not 46. Yep. And phenotypically, he kind of has a distinctive look, right? 10% of the time. Oh, really? 90% of the time, a man with Klinefelter's, you'd never know. Yeah.

So that's the board question. That's the board question, right?

So that's the board question. That's the board question, right?

Meaning they will produce an X or a Y sperm. Just like everyone else. The only difference is they have a two-thirds chance of producing an X and a one-third chance of producing a Y, I'm assuming, instead of 50-50. Don't think we know that.

Meaning they will produce an X or a Y sperm. Just like everyone else. The only difference is they have a two-thirds chance of producing an X and a one-third chance of producing a Y, I'm assuming, instead of 50-50. Don't think we know that.

I interrupted you. You were in the process of explaining how we actually make the sperm, where the tail comes from and the whole process. Yeah, it's all done in the testicle. Yep. It's an amazing machine. Weird question we should maybe get to is why is it out in the breeze like that? I assumed it was temperature related. Why? Why does it need to be a little cooler?

I interrupted you. You were in the process of explaining how we actually make the sperm, where the tail comes from and the whole process. Yeah, it's all done in the testicle. Yep. It's an amazing machine. Weird question we should maybe get to is why is it out in the breeze like that? I assumed it was temperature related. Why? Why does it need to be a little cooler?

I would guess, because I like to make things up, that it's so energetically demanding that it's giving off more heat in the process of creating something that is going to be so efficient to be able to swim 20 miles effectively. And that's very glycolytic, I'm assuming. The amount of ATP that must be generated. 75 mitochondria for sperm. That's like an electric motor on each wheel. Yeah.

I would guess, because I like to make things up, that it's so energetically demanding that it's giving off more heat in the process of creating something that is going to be so efficient to be able to swim 20 miles effectively. And that's very glycolytic, I'm assuming. The amount of ATP that must be generated. 75 mitochondria for sperm. That's like an electric motor on each wheel. Yeah.

So that would be my guess is it's an overheating problem if you tried to keep those guys inside. And I think overheating could be translated to oxidative stress, which is a cause of a lot of infertility.

So that would be my guess is it's an overheating problem if you tried to keep those guys inside. And I think overheating could be translated to oxidative stress, which is a cause of a lot of infertility.

Women can get in hot baths and they're okay. It's funny. I had a buddy over who shall remain nameless. He does not have kids, but he would like to have kids. And we sauna'd the other day. He went up to my freezer beforehand. I didn't really know what he was doing in there. I thought he was getting a drink or something. And he came down with ice packs.

Women can get in hot baths and they're okay. It's funny. I had a buddy over who shall remain nameless. He does not have kids, but he would like to have kids. And we sauna'd the other day. He went up to my freezer beforehand. I didn't really know what he was doing in there. I thought he was getting a drink or something. And he came down with ice packs.

We were sitting in the sauna and he was in the sauna, but he's got ice packs all over his groin. Immediately understood why he was doing that. But yeah, we'll come back to whether or not that's an important strategy for men in saunas who want to have kids. So the complete sperm, spermatogenesis is the whole process.

We were sitting in the sauna and he was in the sauna, but he's got ice packs all over his groin. Immediately understood why he was doing that. But yeah, we'll come back to whether or not that's an important strategy for men in saunas who want to have kids. So the complete sperm, spermatogenesis is the whole process.

Give us some size comparison. Before the tail is on, what is the size of that cell? Probably similar to half the size of a lymphocyte or half the size of a red blood cell, a couple microns.

Give us some size comparison. Before the tail is on, what is the size of that cell? Probably similar to half the size of a lymphocyte or half the size of a red blood cell, a couple microns.