
The Oprah Podcast
Oprah and Dr. Sharon Malone on Everything You Need to Know About Menopause
Tue, 01 Apr 2025
BUY THE BOOK! “Grown Woman Talk” by Dr. Sharon Malone, published by Crown Publishing, is now available wherever books are sold. The paperback version will be available on April 8, 2025. https://www.penguinrandomhouse.com/books/722319/grown-woman-talk-by-sharon-malone-md/ Dr. Sharon Malone, menopause expert, Chief Medical Advisor Alloy Women's Health, and author of the New York Times bestseller, "Grown Woman Talk," joins “The Oprah Podcast” to explain everything you need to know about this natural stage of life that impacts 1 billion women worldwide. Actress Naomi Watts, who writes about her menopausal journey in "Dare I Say It," will also join the conversation to share how she has learned to navigate her marriage, career and motherhood while also dealing with perimenopause. Dr. Malone will give you a greater understanding of the science behind menopause including what it is, why it happens, when it starts and how long it lasts. She will also discuss why women experience such a wide range of symptoms, why hormone fluctuations happen and why hormone replacement therapy can help. Dr. Malone answers questions from women in the throes of menopause including how to deal with workplace bias, how to manage drenching night sweats, what causes those unpredictable mood swings and what we can do to prevent dementia and Alzheimer’s as we age. Alloy Women's Health is a direct to consumer digital healthcare company revolutionizing the way women age by offering education, expertise, and safe, science-backed solutions for perimenopause & menopause symptoms, skincare, sexual health, gut health and more. Treatment plans are customized and everything is delivered with free shipping. Alloy customers receive unlimited follow-up care with their menopause-trained physician through the duration of their active prescription and access to community through member support groups and more all from the convenience of their home. Alloy offers a fast, easy, and 100% digital solution to help women find guidance and treatments wherever they are. Being with Alloy is like having a menopause doctor in one's pocket. https://www.myalloy.com/ Follow Oprah Winfrey on Social: https://www.instagram.com/oprah/ https://www.facebook.com/oprahwinfrey/ Listen to the full podcast: https://open.spotify.com/show/0tEVrfNp92a7lbjDe6GMLI https://podcasts.apple.com/us/podcast/the-oprah-podcast/id1782960381 Learn more about your ad choices. Visit megaphone.fm/adchoices
Chapter 1: Why is menopause a hot topic today?
Thank you all for joining the Oprah Podcast and for watching us on YouTube. I appreciate you taking the time to spend it here with me. And I am just so appreciative of the conversations we're having about things that impact all of our lives. And I'm guessing you all have been hearing a lot about menopause these days.
But the more I talk about it, the more I realize we need a Menopause 101 because there's still so much There's so much confusion still out there, and we need reliable information, and we need facts. Menopause is not a disease or a disorder, but a natural part of aging that all women born with ovaries will eventually experience.
Menopause occurs when a woman has gone 12 months without a period, which means her ovaries have stopped producing hormones and her body is no longer capable of reproduction. For most women, menopause occurs between the ages of 45 and 55. But before you enter menopause, your body will go through a transitional period known as paramenopause, which can begin as early as your mid-30s.
Paramenopause can last anywhere from 4 to 10 years and may include symptoms like hot flashes, fatigue, mood swings, dry skin, dry everything, and low libido. To help us understand more about the menopausal journey, I invited Dr. Sharon Malone to the podcast. Dr. Malone has been a pioneer and nationally renowned expert in menopause for over three decades.
Chapter 2: What are the stages of menopause and their symptoms?
She is the chief medical advisor for Alloy Women's Health and the New York Times bestselling author of Grown Woman Talk. So happy to have you here, Dr. Malone. Thank you so much for having me, Oprah. You know, it's what we were saying before, that I feel like I've been talking about it and talking about it and talking about it. And you say you talk about it. It's every day.
And then there's still all these people who have never heard about menopause and what it means for all of our lives.
Right. You know, even for the women who are out there who are currently going through menopause, they haven't heard this conversation. And there's another 6,000 women every day going into menopause. And so the backfill is constant because there are people that just haven't had this conversation, not with their doctors, not with their mothers, and not even with their friends.
So I'm hoping those of you who are seeing this, if you're watching for yourself, that you pass it on to somebody who you also know needs it. Let's start by you explaining the four stages of women's reproductive and post reproductive lives. Can you walk us through what they are?
Yes.
You do that very well in Grown Talk, but I want you to share it with people who haven't read the book yet.
I would love to. The first stage that we're all familiar with is your premenopausal phase, and that really starts at puberty. And that encompasses your reproductive life, the peak reproductive years, which starts somewhere at 12, 13, and it goes to women when they're early 30s. That's premenopause. So when we're talking about that, that's the concern. Yes.
Then when you become perimenopausal, that is that amorphous phase between being your peak reproductive years and the end of your reproductive years. And the end of reproduction really starts at menopause. So there's this great space in between the perimenopausal years where you start to have some of the symptoms of menopause.
But you're still having your periods, sometimes regularly, sometimes not.
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Chapter 3: How does hormone replacement therapy work?
Absolutely no longer fertile. And sometimes it's not just the complete loss of eggs, it's the loss of function of your eggs. Because the other thing that happens that people don't talk enough about during perimenopause is that there's a change in your fertility.
Because when you're perimenopausal, when you're 40, you still have eggs, you're still having your period, but your fertility is not what it was at 20. It's not what it was at 25. Because you've already lost eggs. It's not because you've lost them. It's because they are less responsive. Oh, they're less functional. They're less functional. And I'll give you an example.
I like to say, you're born with all the eggs you're ever going to have. You don't get any more, you don't make any more. And then over time, you ovulate some, but you're not losing them because you've run out of them. You only ovulate about 500 times in your lifetime, but you had a million when you were born. Those eggs become less functional.
And every woman has a different expiration date stamped on your eggs. So you don't know, are my eggs going to last until I'm 45? Or are they going to expire when I'm 35? And that's why we start to see the fertility changes. And for each individual, when you reach the end of that road, it's going to be different from person to person.
I thank you for taking the time out of your busy day to listen to this episode about our health and well-being. We'll have more of my conversation about menopause with the author of Grown Woman Talk, Dr. Sharon Malone, after these messages.
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Welcome back to more of my conversation with Dr. Sharon Malone about the latest science on menopause. I want to bring in actress and activist Naomi Watts to this conversation. She, too, has a new book, Dare I Say It? Everything I Wish I'd Known About Menopause. It's a New York Times bestseller. Naomi, I hear you're on set. Thank you for joining us. Thank you for having me, Oprah. Yes.
What was the inspiration for you to write it? Because you were going through it or had been through it?
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Chapter 4: What is Naomi Watts' experience with early menopause?
As I understand it, still to this day, doctors are gatekeeping that because of the bad studies in 2002. But my doctor was ahead of the curve, and I've been on HRT successfully and safely for over 10 years.
I know we're going to talk about HRTs with Dr. Malone because there is so much confusion, misconception about HRTs. I've been on them for, I think now, well, for whenever I was 54, that's when I went on HRTs. So I believe them. What is HRT? Can you explain that, Dr. Malone?
Yes, hormone replacement therapy, typically it is comprised of estrogen, which is the secret sauce in hormone replacement therapy, and a progestin, which is the second hormone that you take when you have an intact uterus. Now, for women who've had hysterectomies and don't need to have the progestin, you can just take estrogen alone.
But most of what we associate with the symptomatic relief really comes from the estrogen component.
And I hear some women are also now taking a little bit of testosterone also.
Yes, they are. But all of the studies that have been done really basically are with estrogen and progestin. We are sort of behind the curve. We're finding out a lot more about testosterone because women make testosterone too. And I think that that's sort of the misconception is that, well... Estrogen is a female hormone and testosterone is a male hormone. And that is not true.
Women make almost as much testosterone in the course of our reproductive lives as we make estrogen. That's really responsible for that sex drive that you get right around mid-cycle. So we're coming back around to understanding that maybe there should be more to hormone replacement therapy than just estrogen and progestin. But we need a lot more studies about that.
Okay, we're going to talk more about that. But in your book, I think this is really an interesting aspect, Naomi, because in your book, chapter 12 is titled Minnow Boss and how to deal with ageism in the workplace. What advice would you give menopausal women who...
I think in many cases start to feel invisible at work and also feel a level of embarrassment and shame about going through this change because there is no – number one, they don't understand it and the culture doesn't understand it.
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Chapter 5: How can women address menopause in the workplace?
So imagine going into puberty and not knowing anything about what's going to happen to your body, which a lot of us women did. Nobody had said anything about what a period is and what the hormones were going to do and all of that. And so many women are experiencing the same going into menopause because their doctors don't even know. There's a lack of an awareness and information from doctors.
From what I've learned from you and other doctors, it's not even taught in medical school.
You know, it used to be. And let me say, because, you know, I'm in the old group of people. And, you know, the study that really changed everything in 2002, the Women's Health Initiative, really did an about face on the conversation about menopause. Because let me just say, women have been going through menopause for as long as we've been alive. Yes.
The only thing that's changed historically is that more of us are living long enough to get to this phase of life. But women have complained about menopause forever. But it was thought to be, you know, women just being hysterical with the symptoms or you're losing your mind. Women would go to sanitariums at that point because of the mental illness and the mental distress that it caused women.
But we have known how to treat the symptoms of menopause since 1942. That was when the first estrogen product was introduced. That was Primarin. And so women have been using hormones since 1942, those who had access and the awareness of it. But it really changed everything. In 2002. In 2002. Okay. I was taught about menopause and what to do about it.
And then from 2002 on, doctors who were trained didn't really get that information.
Yes. Yeah. I was talking to Dr. Haver, who was saying she had an hour of training about it, a discussion about it, and was in another session that lasted six hours. So you come out of medical school with seven hours of training. So Since 2002, doctors have been trained about it.
And obviously, so many doctors even, I think, are still confused about the Women's Health Initiative study done in 2002, which said, can you clear that up for us to understand what actually happened? This is one of the reasons. The reason why this is so important is because this 2002 study is the reason why so many people are afraid of hormone replacement therapy.
Exactly. In a nutshell, you know, as I told you, 1942, we've been treating women who were symptomatic during menopause, typically the hot flashes and the mood swings, with an estrogen product. It worked. So as we sort of got more women who were taking hormones, we found that there were some tweaks that need to be made along the way and added the progestin component to it.
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Chapter 6: What was the impact of the 2002 Women's Health Initiative study?
Well, I would understand why. Yes. Because I remember I was doing the Oprah show when this happened and it was a big announcement and everybody was like, oh, that's it. Exactly. Hormone replacement therapy is dangerous. It causes cancer. And now what we're hearing, what I hear you saying, and I've heard other doctors say, this was a flawed study. Yes.
It was a very much misinterpreted study because if you had said, I don't disagree, okay, your data is your data. If you start women on hormone therapy later in life, you're not going to prevent their heart disease. I think that's probably true. The problem is that they generalize that data to everybody. Well, what about a 50-year-old?
Well, what about if I start it when I'm 45, whenever I'm menopausal? Because that's when we clinically would start it. Yes, yes, yes. That's a very different outcome. And that was the misinterpretation of taking very limited findings and applying it to everyone.
But it became the narrative. It's what people believe. It's the reason why my best friend still won't do an HRT because she's like, she wrote about her in the book, still won't do an HRT because she's like, I don't know, I think it causes cancer.
It has been, when you say the words breast cancer... to women, I think that is their number one fear, is breast cancer, despite the fact that the number one cause of deaths in women is cardiovascular disease. It is more than all cancers combined and all accidental causes of death for women.
And do we know for sure that HRT, that hormone replacement therapy, helps now cardiovascular issues with women?
There is everything. When you take that same data, the largest study ever done, and you exclude the women who are older and only apply it to the women who are under 60? Yes. And within 10 years of menopause, guess what they find?
The same findings that we had from the observational study that the cumulative data says that if you start hormone therapy within 10 years of your last period or before age 60, you decrease the risk of cardiovascular disease by anywhere from 30 to 50%. Wow. Yeah, wow.
We've got people joining us on Zoom with questions. Trisha and her husband, Stephen, are joining us from Edina, Minnesota. What's going on with you, Trish?
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