
Our immune system operates like a finely tuned symphony, yet many of us find ourselves out of harmony, vulnerable to persistent infections, autoimmune conditions, and chronic disease. Rather than merely suppressing symptoms, a Functional Medicine approach seeks to identify and address the underlying disruptions driving immune imbalance. Central to this dysfunction is compromised gut health, which undermines immune regulation, while mitochondrial impairment and chronic inflammation further erode the body's capacity for resilience and repair. By restoring balance at the root level, we can cultivate a more robust and adaptive immune system. In this episode, I discuss, along with Dr. Elroy Vojdani and Dr. Leonard Calabrese, how cleaning up our diets, improving gut health, removing toxins, and decreasing stress can do wonders for our immune systems. Dr. Elroy Vojdani is a pioneer in the field of functional medicine and research and is the founder of Regenera Medical, a concierge functional medicine practice in Los Angeles, California. He graduated from USC Keck School of Medicine, is a certified Institute for Functional Medicine Practitioner. Dr. Vojdani has conducted medical scientific research for decades with more than 25 publications in multiple peer-reviewed journals. He is also world-renowned for his research and development of state-of-the-art lab testing in the field of immunology. He recently authored a book entitled “When Food Bites Back” which discusses the role of food immune reactions in the development of autoimmune disease. Dr. Leonard Calabrese, is an expert in immunology and rheumatology. In fact, he is a Professor of Medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and Vice Chair of the Department of Rheumatic and Immunologic Diseases. Dr. Calabrese is the director of the RJ Fasenmyer Center for Clinical Immunology at the Cleveland Clinic and holds joint appointments in the Department of Infectious Diseases and the Wellness Institute. Dr. Calabrese has made significant contributions to science in the fields of chronic viral infections and autoimmunity and vascular inflammatory diseases of the brain. He has received numerous awards and honors for his contributions to the advancements of immunology and wellness. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: Boost Your Immunity with These Simple Steps How To Reset Your Immune System At A Cellular Level The Secrets to Creating a Healthy Immune System
Full Episode
Coming up on this episode of The Dr. Hyman Show. 60% of your immune system is right underneath the lining of your gut. So it's there because you're exposed to foreign molecules from food and bugs, and your immune system is the first line of defense. And so when that system gets disrupted, If you get what we call a leaky gut, it creates a lot of inflammation.
And so changing your diet has a huge impact on there, working on your inner guard and your gut microbiome. Did you know that over 75% of people are deficient in magnesium? That's a problem because magnesium is essential for over 600 functions in your body, including energy production, stress regulation, and deep sleep. Here's the catch. Not all magnesium is created equal.
Most supplements only contain one or two forms, but Magnesium Breakthrough by Bioptimizers gives you all seven essential forms in one capsule. So your body gets exactly what it needs, where it needs it. I take Magnesium Breakthrough every night, and I've noticed a huge difference in my sleep, stress, and muscle recovery. It's a game changer.
Right now, Bioptimizers is offering my listeners a special discount. Just go to bioptimizers.com slash hymen and use code HYMEN10 at checkout. Don't wait. Your body will thank you. It plays a big role. Now, before we jump into today's episode, I'd like to note that while I wish I could help everyone by my personal practice, there's simply not enough time for me to do this at scale.
And that's why I've been busy building several passion projects to help you better understand, well, you. If you're looking for data about your biology, check out Function Health for real-time lab insights. And if you're in need of deepening your knowledge around your health journey, well, check out my membership community, Dr. Hyman Plus.
And if you're looking for curated, trusted supplements and health products for your health journey, visit my website, drhyman.com, for my website store and a summary of my favorite and thoroughly tested products. What are the things that help us have immune resilience?
And what are the things that have changed in our environment, our life, our lifestyle that have actually made our immune systems be dysregulated?
Yeah, the most important cell in the immune system is something called a T regulatory cell. And the dominant population of T regulatory cells in an adult lives in the lining of the gut. So the gut is the center of immune resilience. Those regulatory cells are responsible for
you know, kind of balancing all the different sides, making sure that, you know, in an inflammatory attack against something that we should be attacking, we don't end up in that mistake of attacking ourselves. So the gut is absolutely the center of the immune system and immune resilience.
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