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Lex Fridman Podcast

#475 – Demis Hassabis: Future of AI, Simulating Reality, Physics and Video Games

23 Jul 2025

Description

Demis Hassabis is the CEO of Google DeepMind and Nobel Prize winner for his groundbreaking work in protein structure prediction using AI. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep475-sc See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc. Transcript: https://lexfridman.com/demis-hassabis-2-transcript CONTACT LEX: Feedback - give feedback to Lex: https://lexfridman.com/survey AMA - submit questions, videos or call-in: https://lexfridman.com/ama Hiring - join our team: https://lexfridman.com/hiring Other - other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: Demis's X: https://x.com/demishassabis DeepMind's X: https://x.com/GoogleDeepMind DeepMind's Instagram: https://instagram.com/GoogleDeepMind DeepMind's Website: https://deepmind.google/ Gemini's Website: https://gemini.google.com/ Isomorphic Labs: https://isomorphiclabs.com/ The MANIAC (book): https://amzn.to/4lOXJ81 Life Ascending (book): https://amzn.to/3AhUP7z SPONSORS: To support this podcast, check out our sponsors & get discounts: Hampton: Community for high-growth founders and CEOs. Go to https://joinhampton.com/lex Fin: AI agent for customer service. Go to https://fin.ai/lex Shopify: Sell stuff online. Go to https://shopify.com/lex LMNT: Zero-sugar electrolyte drink mix. Go to https://drinkLMNT.com/lex AG1: All-in-one daily nutrition drink. Go to https://drinkag1.com/lex OUTLINE: (00:00) - Introduction (00:29) - Sponsors, Comments, and Reflections (08:40) - Learnable patterns in nature (12:22) - Computation and P vs NP (21:00) - Veo 3 and understanding reality (25:24) - Video games (37:26) - AlphaEvolve (43:27) - AI research (47:51) - Simulating a biological organism (52:34) - Origin of life (58:49) - Path to AGI (1:09:35) - Scaling laws (1:12:51) - Compute (1:15:38) - Future of energy (1:19:34) - Human nature (1:24:28) - Google and the race to AGI (1:42:27) - Competition and AI talent (1:49:01) - Future of programming (1:55:27) - John von Neumann (2:04:41) - p(doom) (2:09:24) - Humanity (2:12:30) - Consciousness and quantum computation (2:18:40) - David Foster Wallace (2:25:54) - Education and research PODCAST LINKS: - Podcast Website: https://lexfridman.com/podcast - Apple Podcasts: https://apple.co/2lwqZIr - Spotify: https://spoti.fi/2nEwCF8 - RSS: https://lexfridman.com/feed/podcast/ - Podcast Playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 - Clips Channel: https://www.youtube.com/lexclips

Audio
Transcription

Full Episode

0.031 - 28.334 Lex Fridman

The following is a conversation with Demis Hassabis, his second time on the podcast. He is the leader of Google DeepMind and is now a Nobel Prize winner. Demis is one of the most brilliant and fascinating minds in the world today, working on understanding and building intelligence and exploring the big mysteries of our universe. This was truly an honor and a pleasure for me.

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29.676 - 54.085 Lex Fridman

And now a quick few second mention of each sponsor. Check them out in the description or at lexfriedman.com slash sponsors. It's the best way to support this podcast. We've got Hampton for connecting with founders and CEOs, Finn for AI customer service, Shopify for building e-commerce businesses, Element for daily electrolytes, and AG1 for your health. Choose wisely, my friends.

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54.065 - 77.78 Lex Fridman

And now on to the full ad reads. I do try to make them interesting, but if you must skip, friends, please still check out our sponsors. I enjoy their stuff, maybe you will too. And also, to get in touch with me, for whatever reason, go to lexfreeman.com slash contact. All right, let's go. This episode is brought to you by Hampton, a private community for high growth founders and CEOs.

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78.321 - 95.26 Lex Fridman

That's the interesting thing about starting a company and running a company, especially one that's growing really quickly, has to hire a lot, has to scale a lot. It's perhaps a little bit counterintuitive, but for the founder, it can be deeply lonely. I suppose that's one of the reasons they recommend to have a co-founder, but

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95.24 - 121.191 Lex Fridman

Even outside of that, there's just a deep loneliness with putting it all on the line, risking everything, knowing that the chances of success are low, But if you do succeed, the gains are huge. And you have your heart in it. You have your dreams in it. You believe in it. But also there's a constant rollercoaster of fear and doubt and hope and moments of triumph and moments of failure.

121.252 - 138.626 Lex Fridman

All those go back and forth and just this constant psychological turmoil. Anyway. Through all that, it's just nice to connect with other people that are going through the same thing, and that's what Hampton is about. It does a thing where every month, eight founders face-to-face have real conversations about their daily struggles.

139.167 - 163.695 Lex Fridman

Groups are forming in a bunch of places, New York City, Austin, San Francisco, LA, Miami, Denver, and so on. If you are a founder who's tired of carrying it all alone, visit joinhampton.com to see if it's a fit for you. That's joinhampton.com. This episode is also brought to you by Finn. It's an AI agent for customer service.

164.135 - 170.722 Lex Fridman

So they are focused, laser focused on the customer service application, and they want to do that better than anybody else in the world.

171.562 - 194.403 Lex Fridman

In fact, if you measure by the metric of the number of resolutions, so when you have the agent resolve the customer service issue, that's resolution, they have a 59% average resolution rate, which makes it the highest performing customer service agent on the market. It's trusted by over 5,000 customer service leaders and even top AI companies, including Anthropic.

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