Digital Social Hour
How This Simple Test Could Add Years to Your Life | Panos DSH #1223
Fri, 07 Mar 2025
Discover how this simple test could add years to your life! 🌟 Join Sean Kelly on the Digital Social Hour as he dives into a fascinating conversation with Panos from PNOE about the groundbreaking 7-minute breath analysis test. 🫁✨ Learn how understanding your breathing, metabolism, and VO2 max could transform your health, optimize your fitness, and even predict your biological age. 🕒💪 Packed with valuable insights on sleep apnea, cardio vs. strength training, and the power of biohacks like hyperbaric oxygen therapy, this episode is a must-watch for anyone looking to supercharge their longevity. 🌱 From nasal breathing tips to the four pillars of living longer and stronger, Panos shares the secrets to unlocking your body’s full potential. 🚀 Don’t miss out on this eye-opening conversation! Watch now and subscribe for more insider secrets. 📺 Hit that subscribe button and stay tuned for more transformative health tips on the Digital Social Hour with Sean Kelly! 💡🎉 Join the conversation in the comments below and share how YOU plan to optimize your health. 👇 CHAPTERS: 00:00 - Intro 00:34 - What is VO2 Max 03:26 - How Breathing Affects Health 07:17 - Athletes with Best VO2 Max Results 15:21 - How Lumen Started 20:45 - AI for Personalized Nutrition & Training 26:25 - PNOE's Presence in Greece 31:47 - What's Next for Panos 32:14 - Final Thoughts APPLY TO BE ON THE PODCAST: https://www.digitalsocialhour.com/application BUSINESS INQUIRIES/SPONSORS: [email protected] GUEST: Panos https://linktr.ee/PNOE https://www.instagram.com/pnoe_analytics https://pnoe.com/ LISTEN ON: Apple Podcasts: https://podcasts.apple.com/us/podcast/digital-social-hour/id1676846015 Spotify: https://open.spotify.com/show/5Jn7LXarRlI8Hc0GtTn759 Sean Kelly Instagram: https://www.instagram.com/seanmikekelly/ #cancerbiomarkers #cysticfibrosis #sleepapnea #volatileorganiccompound #chemicalexposure
Chapter 1: What is the importance of breath analysis in health?
Thank you so much for having me, Kelly.
Yeah. So I just did one of your tests, right? And it was a seven minute test. Could you explain what happened?
Chapter 2: How does the 7-minute breath analysis test work?
Yeah, absolutely. So Panoi is a seven to 10 minute breath analysis test. You put a mask on, you breathe normally. And what the device does is that it analyzes how much oxygen you are consuming and how much carbon dioxide you're producing. And this is one of the most fundamental processes in the human body because oxygen has to be delivered to the cells for metabolism to happen.
Metabolism is the process by which your cells will use oxygen to break down nutrients, that is the fats and carbs you get from the food that you eat. to release the energy that your body needs to survive, thrive, and do whatever daily functions you do. And if you think about it, every single major system and organ in our physiology developed to specifically support this function.
You have lungs to absorb oxygen. You have a heart and a circulatory system to pump it. You have mitochondria to use it. And then you have a nervous system to coordinate all of that. And so breath analysis, which is a test we did, is actually the only assessment known to science that can reliably assess all of that process. And so it's a 10-minute test, produces 23 biomarkers.
And through these 23 biomarkers, by collectively analyzing them, we can paint the picture of how efficiently your lungs, your heart, your cells, your metabolism, and your nervous system are working. And some of these biomarkers are quite famous, like view to max test or resting metabolic rate test.
That's why a lot of people tend to know this assessment as a view to max test or a resting metabolic rate test. But there's a lot more to it, you know, as you just saw from the test that we did. And so, for example, this test is the only one that can tell you how efficiently you burn fats and carbs and how many fats and carbs your body's burning.
It's also a test that can very reliably identify your biological age because view to max, according to the American Heart Association, is one of the best indicators for how long and well someone is going to live. So overall, it's an assessment that has been around for about 100 years up until we came along. It was very much in the sidelines for many reasons. We can talk about that.
But it is because of the fact that it looks into so many different areas of physiology, an assessment that has very established clinical utility in the world of cardiology, in the world of pulmonology, endocrinology, sports science, and nutrition science.
Yeah. I just learned the importance of lifting weights, man.
Yeah.
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Chapter 3: How can breathing habits influence long-term health?
We're going to throw up my results on the screen, but basically my, my age was four years above my real age. So I've got some work to do and I thought I was pretty healthy.
Yeah.
So that was pretty interesting.
You know, people like you that, you know, are typically healthy, you know, may have gone through certain health stuffs in the past, but you know they don't really know if there's any residual damage or things they need to be concerned about when it comes to things of the past.
tend to have lingering issues that may be impacting what we call the oxygen flow through the body at that particular point in time. And although that may not be a clinically relevant thing and may not be considered a disease if you were to go to the doctor, it is something that long-term can present certain issues and evolve into some sort of chronic disease or major health event.
So there's actually a lot of people out there that would be generally considered fit, but there is stuff to work on. And that stuff isn't just superficial. It is something that would be considered important to deal with because 10 years or 20 years down the road, it may end up being something considerable.
I would say, because we've done like hundreds of thousands of tests up until now as a company, one of the most important things that...
people have as a problem that they're unaware of is some sort of anatomical issue with their breathing apparatus and i use the term breathing apparatus because you know it's not just the lungs but it's the diaphragm it's the respiratory muscles it's the nose it's the mouth it's you know the entire chain that enables oxygen to be absorbed right
So there's a lot of people that develop mouth abnormalities that may lead to sleep apnea. And because that is mild at that point, it's not something that is clinically relevant. We have a lot of people that we test that have some sort of deviated septum that is obstructing them from breathing from their nose.
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Chapter 4: Which athletes have the best VO2 Max results?
But once we dive and we double click into the components of the oxygen chain, right, your lungs, your heart and your cells, we uncover certain things that, as I said, may not be relevant now and may not be life debilitating now, but 10 years or 20 years down the road may very well be.
Yeah, I think that's what happened in my case. I had some nasty bronchitis during the pandemic and I actually just found out I'm allergic to penicillin now because they put me on so many antibiotics for growing up. So yeah, you got to take these tests. They're really important. You mentioned a few things earlier. I did want to ask this first though.
So since you've done hundreds of thousands of tests, I'm curious which athletes had the best result, which sport?
So, I mean, as expected, sports that have a lot of cardio and endurance component in them will typically yield athletes that score better in their view to max. But, you know... What's also very important for people to understand is that every type of exercise is going to impact our biology differently.
So if you're looking to have great mitochondrial function and great fat burn efficiency, doing endurance and zone two training and steady state cardio is going to be your best bet. But if you want to have a high metabolism, lifting weights is going to be better. So-
You may run into an endurance athlete that has incredible view to max, very good fat burn efficiency because they do a ton of cardio and a ton of steady state, low intensity cardio. But that person may not have a great metabolic rate because, you know, as a matter of fact, doing a lot of cardio will suppress your metabolic rate, right? Because your body is being asked to cover large distances.
And so it is becoming more economical because it's trying to conserve energy, right? And so on the flip side of things, you can run into bodybuilding athletes, right? That have great metabolic rates because they have huge muscles and, you know, they're also the muscle composition is such that enables them to burn more.
The type of training you do will also impact the type of muscle that you end up developing. But these people will end up having not great fat burn efficiencies. So to your point earlier, yeah, every type of sport is going to optimize your biology in one particular area. But it's very difficult to have like the super well-rounded, perfect athlete that is almost optimal in all different areas.
What I've observed is that, at least in the world of triathlon and high rocks now, that is becoming a very big trend.
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Chapter 5: What inspired the creation of PNOE?
Fairly common. You know, there's, you know, people that have had accidents. There's many reasons that can lead to something like that.
Yeah. I know sleep apnea and sleeping issues overall are getting pretty common too. And a lot of it has to do with breathing, right?
Yeah. Yeah. uh there's a very big uh comorbidity with the fact that we are chewing food that is a lot softer than what it used to be james nestor in his book about breathing talks about that a lot and it is so true you know um the fact that we're not consuming food that is natural is also certainly a contributor to the fact that we are seeing the sleep apnea epidemic that
Because of this strong comorbidity with neurodegenerative diseases, ultimately, I think we're going to see a very big rise in, unfortunately, neurodegenerative conditions down the road for our generation, which we haven't yet seen. Right now, we're just seeing the first wave of symptoms, which is sleep apnea.
But there are, as I said, second and third order effects that will unavoidably start to occur down the road. That's scary, man. That's scary, I know, yeah.
Is that a big reason why you started this company?
So how we started as a company, it's so interesting. So I personally have no background in health. I did my first degree in mechanical engineering. That was back in Greece. Came to the US, did my graduate degree at Stanford. That was in engineering again. I went into big tech. I was working in enterprise data centers and then Oracle for a little bit. And then my co-founder, Apostolos,
He's my first friend in life, actually. We met first year, first day of elementary school. That's awesome. So we've known each other since the age of six. So we went through elementary, middle school, high school together. Also undergrad. I was in the mechanical engineering school. He was doing applied physics and math. He then went on to Cambridge, UK.
focusing to do his PhD on sensing technologies. And when he was there, he discovered the amazing world of breath analysis. Breath analysis is at the same time, such an old, but also such a new field. All because this type of breath analysis called cardiometabolic testing has been around for about a hundred years. And he was like, this is such an important thing.
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Chapter 6: How has PNOE made breath analysis more accessible?
um and uh i always wanted to do something of my own and you know i found that that was like a very interesting idea and we started working on that together uh as i said we were like the first company to create a device that provides this assessment in an easy and practical way for the average clinic and so uh that made the test a lot easier
But then the other problem that we uncovered as we made the test easier is that the analysis, the interpretation, and also the prescription based on the information coming out of the test was also a very big issue because, as I said,
This test had been around for about 100 years, but it remained at the sidelines for decades, despite the fact that if you look at the clinical literature, there's so much information to establish it as a very, very important assessment.
And so to address that, we made the hardware cheaper, more practical, more affordable, but then we also built the entire ecosystem of services and software to streamline the process for analyzing the data and then providing wellness prescription, nutrition training, bioptimization.
so that clinics don't have to hire an entire team of experts to be able to analyze the information because the reality is that there's so much information coming out of your breathing and the time requirements and the certification and the skills and expertise required to analyze all the data pretty much made it cost prohibitive for the average clinic.
That makes sense. That's probably why they didn't adopt it on a mass scale, right? Yeah. Because growing up, I was never taught to do this type of test. No one ever brought it up.
Exactly. And even like, you know, varsity athletes or professional athletes haven't even done the test. It's crazy.
Wow. Now they probably are.
Now there's obviously a big trend and, you know, it's very important that People like Peter Attia, Andrew Huberman, and so many others are talking about the value of Vue 2 Max, but it was because the hardware was very expensive and impractical, and also analyzing data was also very difficult and costly that kept that from entering mainstream adoption. And because we made it...
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