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Dr. Peter Attia

👤 Person
11178 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And it looks like it's algebraic. This is incredible. It's easier for me to think about these things graphically than to think that it basically shuts off at about eight hours. So I'll give some more physiology.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And it looks like it's algebraic. This is incredible. It's easier for me to think about these things graphically than to think that it basically shuts off at about eight hours. So I'll give some more physiology.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And then we checked the first... Sorry, dumb question. Why didn't they just measure the ejaculate? Why did they have to biopsy the testes? I'm not sure. They just wanted to know about spermatogenesis, but we didn't want to biopsy the testes. They actually wanted to torture the guys, but...

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And then we checked the first... Sorry, dumb question. Why didn't they just measure the ejaculate? Why did they have to biopsy the testes? I'm not sure. They just wanted to know about spermatogenesis, but we didn't want to biopsy the testes. They actually wanted to torture the guys, but...

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So let's now define infertility. We've been using this term quite a bit. I suspect it actually has a formal definition. It's one year of inability to conceive after sex, using sex.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So let's now define infertility. We've been using this term quite a bit. I suspect it actually has a formal definition. It's one year of inability to conceive after sex, using sex.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

When someone shows up in your office, is it usually after they've gone down the rabbit hole of troubleshooting the female partner, or are people doing this in parallel?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

When someone shows up in your office, is it usually after they've gone down the rabbit hole of troubleshooting the female partner, or are people doing this in parallel?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Okay. Let's talk about your workup. What do you do when a guy comes in and what are the things you want to know about him? So getting a guy in is great.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Okay. Let's talk about your workup. What do you do when a guy comes in and what are the things you want to know about him? So getting a guy in is great.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Can you explain what that, we haven't talked about how a vasectomy works and why a guy still ejaculates, but is infertile. Explain what the vas deferens, how the whole thing works in the plumbing. Right. So we didn't answer that question, which was what's the semen consist of?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Can you explain what that, we haven't talked about how a vasectomy works and why a guy still ejaculates, but is infertile. Explain what the vas deferens, how the whole thing works in the plumbing. Right. So we didn't answer that question, which was what's the semen consist of?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And it gets forced out with muscular contractions in seconds. Yeah. So therefore, if the vas deferens is clipped... you're getting essentially 90% of the volume. You're just missing the 10% of the volume that contains the payload.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And it gets forced out with muscular contractions in seconds. Yeah. So therefore, if the vas deferens is clipped... you're getting essentially 90% of the volume. You're just missing the 10% of the volume that contains the payload.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So physical exam, do you need an ultrasound? How are you able to detect if a person is congenitally missing a vas deferens? Pure physical exam. What, you feel it? Mm-hmm. Interesting.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So physical exam, do you need an ultrasound? How are you able to detect if a person is congenitally missing a vas deferens? Pure physical exam. What, you feel it? Mm-hmm. Interesting.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

What percentage of men are congenitally missing their VAS? One in 500. One in 500, okay.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

What percentage of men are congenitally missing their VAS? One in 500. One in 500, okay.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Okay, so what's the Venn diagram of cystic fibrosis and congenital lacking vas deferens? The genes for that were discovered.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Okay, so what's the Venn diagram of cystic fibrosis and congenital lacking vas deferens? The genes for that were discovered.