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Dr. Peter Attia

👤 Person
11178 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

But is there a frequency of ejaculation that is too much that if a guy is, say, ejaculating every single day, is that insufficient to get a complete replenishment where if he's having infertility, you would say, you got to move it to every other day or whatever the number is?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

But is there a frequency of ejaculation that is too much that if a guy is, say, ejaculating every single day, is that insufficient to get a complete replenishment where if he's having infertility, you would say, you got to move it to every other day or whatever the number is?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

To optimize. Right.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

To optimize. Right.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

but your motility will fall because it's older. There's a min-max curve that you're optimizing for, which you would say is... Three days would be about right.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

but your motility will fall because it's older. There's a min-max curve that you're optimizing for, which you would say is... Three days would be about right.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

If ovulation is day 15, how could a day 11 sperm survive four days? It's nurtured once it's past the vagina. But how many of them are surviving? Is it literally the lone wolf or is it the last hundred? Maybe. Some of the sperm bind to the oviduct and wait.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

If ovulation is day 15, how could a day 11 sperm survive four days? It's nurtured once it's past the vagina. But how many of them are surviving? Is it literally the lone wolf or is it the last hundred? Maybe. Some of the sperm bind to the oviduct and wait.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Fallopian tubes.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Fallopian tubes.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

The fallopian tube, essentially. Yeah.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

The fallopian tube, essentially. Yeah.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Because if there's no egg, they'll just sit there. So again, going back to our moon analogy, this is after you've done stage one, stage two, stage three, you're now out of gravity, right? Like it's actually not an energetics problem anymore. Right. Or a death star problem, right? That's right. You've escaped the hostile environment, in this case of gravity. So now it's a fun place.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Because if there's no egg, they'll just sit there. So again, going back to our moon analogy, this is after you've done stage one, stage two, stage three, you're now out of gravity, right? Like it's actually not an energetics problem anymore. Right. Or a death star problem, right? That's right. You've escaped the hostile environment, in this case of gravity. So now it's a fun place.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

It's the right pH. It's warm. So do we have a sense? This would be a very interesting experiment. of what is the longest duration that a sperm could survive for conception. In other words, to do the experiment, let's just make it as a thought experiment.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

It's the right pH. It's warm. So do we have a sense? This would be a very interesting experiment. of what is the longest duration that a sperm could survive for conception. In other words, to do the experiment, let's just make it as a thought experiment.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

You had a large number of women that you knew were going to ovulate on day 15, and then you would have them have intercourse on day seven, eight, nine, 10, and you create a histoplot or a distribution of what's the frequency of pregnancy across those things and ask what's the bottom fifth percentile, which is the

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

You had a large number of women that you knew were going to ovulate on day 15, and then you would have them have intercourse on day seven, eight, nine, 10, and you create a histoplot or a distribution of what's the frequency of pregnancy across those things and ask what's the bottom fifth percentile, which is the

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

theoretical possibility yeah that's a good one and then the same thing after you want to develop the bell curve of the whole thing well we know that once the egg is ovulated about eight hours and then it's over this is a very important point it really needs to be front if it's only eight hours of survival after ovulation about eight hours it's dead if it's not this is a very very left tail curve correct ah i did not know that so you want the sperm there ahead of time

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

theoretical possibility yeah that's a good one and then the same thing after you want to develop the bell curve of the whole thing well we know that once the egg is ovulated about eight hours and then it's over this is a very important point it really needs to be front if it's only eight hours of survival after ovulation about eight hours it's dead if it's not this is a very very left tail curve correct ah i did not know that so you want the sperm there ahead of time