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Dr. Peter Attia

👤 Person
11178 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

I really don't. So let's go back to the Clomid HCG route. What is the extent to which fertility is preserved when a man is on one of those agents? So Clomid is, we give it for fertility all the time. So it's very good.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

I really don't. So let's go back to the Clomid HCG route. What is the extent to which fertility is preserved when a man is on one of those agents? So Clomid is, we give it for fertility all the time. So it's very good.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And then your fertility is preserved. 1500 three times a week of HCG is a whopping dose. Mm-hmm. You're saying beneath that, you typically don't have issues with FSH and LH suppression? Right. LH you will, because it's LH, but not FSH. Maybe 1,000 to 1,500, you start seeing it. So that's the way you protect the fertility. And what dose of Clomid will you give on top of that regimen? Depends.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And then your fertility is preserved. 1500 three times a week of HCG is a whopping dose. Mm-hmm. You're saying beneath that, you typically don't have issues with FSH and LH suppression? Right. LH you will, because it's LH, but not FSH. Maybe 1,000 to 1,500, you start seeing it. So that's the way you protect the fertility. And what dose of Clomid will you give on top of that regimen? Depends.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

I mean, usually half a pill a day. Half a 25, half a 50? 50 milligram pills, yes. Usually half. You'd give 25 every day? Huh? These are staggering doses. How high are these guys' testosterone getting? The testosterone is driven mainly by the HCG.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

I mean, usually half a pill a day. Half a 25, half a 50? 50 milligram pills, yes. Usually half. You'd give 25 every day? Huh? These are staggering doses. How high are these guys' testosterone getting? The testosterone is driven mainly by the HCG.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Yeah, yeah, yeah. No, it's interesting. I mean, we don't like clomiphene at all. Just because, well, there are a whole bunch of reasons, but they have to do with kind of lipid stuff. Even when we would use it, we would probably use 53 times a week. So that's about the same, right? 25 a day. But for most guys, that would be sufficient alone, even without HCG.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Yeah, yeah, yeah. No, it's interesting. I mean, we don't like clomiphene at all. Just because, well, there are a whole bunch of reasons, but they have to do with kind of lipid stuff. Even when we would use it, we would probably use 53 times a week. So that's about the same, right? 25 a day. But for most guys, that would be sufficient alone, even without HCG.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So I think there's another reason, Paul, and it's everything you just said, but the HCG and testosterone are schedule four, which means you cannot prescribe them through these testosterone clinics that don't even see patients and are literally just not being doctors. They're just sort of giving it to anybody who shows up and pays. It's a coin-operated testosterone dispensary.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So I think there's another reason, Paul, and it's everything you just said, but the HCG and testosterone are schedule four, which means you cannot prescribe them through these testosterone clinics that don't even see patients and are literally just not being doctors. They're just sort of giving it to anybody who shows up and pays. It's a coin-operated testosterone dispensary.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

But Clomid, and I assume by extension, and Clomiphene are not scheduled. which means you can coin operate those. And my guess is that's probably why the FDA is saying what it's saying. It's already bad enough that the Clomid cat is out of the bag, but we don't want to put another one of these unscheduled drugs out there in the land of shady medicine.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

But Clomid, and I assume by extension, and Clomiphene are not scheduled. which means you can coin operate those. And my guess is that's probably why the FDA is saying what it's saying. It's already bad enough that the Clomid cat is out of the bag, but we don't want to put another one of these unscheduled drugs out there in the land of shady medicine.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

The indications are pretty clear and they're really safe.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

The indications are pretty clear and they're really safe.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And what are the approximate levels for each of those?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And what are the approximate levels for each of those?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So most guys that are having difficulty with erections are above 290. There's some other issue. Usually. Yeah. But you have to prove it to them. And I'm fine with that as long as it's safe.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So most guys that are having difficulty with erections are above 290. There's some other issue. Usually. Yeah. But you have to prove it to them. And I'm fine with that as long as it's safe.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

You start seeing issues- With how much FSH and LH? I don't know. Okay. Obviously the other thresholds would be anabolic capacity, like muscle mass and things of that nature. And mood tends to be a lot more variable in my mind. Absolutely.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

You start seeing issues- With how much FSH and LH? I don't know. Okay. Obviously the other thresholds would be anabolic capacity, like muscle mass and things of that nature. And mood tends to be a lot more variable in my mind. Absolutely.