Dr. Peter Attia

It just seems to me that in this day and age with people reproducing at older and older ages, we shouldn't just assume that because we've developed a drug for blood pressure or diabetes, that it's not going to be used by people with fertility. I'll give you a silly example. Have GLP-1 agonists been tested for fertility? No, because it's sort of an off-label use of a diabetic medication. off-label.

It just seems to me that in this day and age with people reproducing at older and older ages, we shouldn't just assume that because we've developed a drug for blood pressure or diabetes, that it's not going to be used by people with fertility. I'll give you a silly example. Have GLP-1 agonists been tested for fertility? No, because it's sort of an off-label use of a diabetic medication. off-label.

It's an on-label use today. But it looks like it might be helping with fertility. But even if it was on-label, I mean, I'm just using that as one example of a drug that was initially approved when we thought, ah, this is going to be for people who are not having kids. But the truth of it is you're going to have lots of people that are trying to reproduce on many of these drugs.

It's an on-label use today. But it looks like it might be helping with fertility. But even if it was on-label, I mean, I'm just using that as one example of a drug that was initially approved when we thought, ah, this is going to be for people who are not having kids. But the truth of it is you're going to have lots of people that are trying to reproduce on many of these drugs.

Absolutely.

Absolutely.

Yeah.

Yeah.

Why don't we just talk about some of those things then now? So this is, I'm sure, a contentious topic, but as you know, lots of discussion around microplastics. So I don't know how far we want to go down that rabbit hole. I recently did a podcast on this topic. I didn't really touch on fertility because I just didn't see any great evidence.

Why don't we just talk about some of those things then now? So this is, I'm sure, a contentious topic, but as you know, lots of discussion around microplastics. So I don't know how far we want to go down that rabbit hole. I recently did a podcast on this topic. I didn't really touch on fertility because I just didn't see any great evidence.

I talked more about things where I thought there was a little bit more evidence. Obviously, with the microplastic story, there's quite a bit of smoke, but there's no real fire. My conclusion from the analysis was there is enough smoke that takes steps where they are reasonable and reduce your exposure to these things.

I talked more about things where I thought there was a little bit more evidence. Obviously, with the microplastic story, there's quite a bit of smoke, but there's no real fire. My conclusion from the analysis was there is enough smoke that takes steps where they are reasonable and reduce your exposure to these things.

So everything from microplastics to PFAS chemicals to phthalates and even the PM2.5s, like there's no reason to expose yourself unnecessarily to this. If you can take relatively straightforward steps, eliminate 60 to 80% of it in your life, do it. Tell me what your impression is of the effect of any or all of the above on fertility.

So everything from microplastics to PFAS chemicals to phthalates and even the PM2.5s, like there's no reason to expose yourself unnecessarily to this. If you can take relatively straightforward steps, eliminate 60 to 80% of it in your life, do it. Tell me what your impression is of the effect of any or all of the above on fertility.

And what is your advice to a guy when you're giving him counsel on everything he can do? We're going to talk about everything, but on this particular domain, if he says, hey, should I stop drinking Starbucks coffees in those plastic cups with the plastic lids? And should I get a reverse osmosis filter in the house? Like, where are you telling him to draw that line?

And what is your advice to a guy when you're giving him counsel on everything he can do? We're going to talk about everything, but on this particular domain, if he says, hey, should I stop drinking Starbucks coffees in those plastic cups with the plastic lids? And should I get a reverse osmosis filter in the house? Like, where are you telling him to draw that line?

I'm not great at that because the stress level goes up so much.

I'm not great at that because the stress level goes up so much.

Should have had a pretty good. Total T, 220 nanograms per deciliter. Did you measure LH? It's probably low. Yeah, I'm sure FSH and LH were totally low. I don't remember what they were. Free testosterone of like three to four. Well, the sleep deprivation, the stress.

Should have had a pretty good. Total T, 220 nanograms per deciliter. Did you measure LH? It's probably low. Yeah, I'm sure FSH and LH were totally low. I don't remember what they were. Free testosterone of like three to four. Well, the sleep deprivation, the stress.