Dr. Peter Attia

And this is something that's standardized and automated through microfluidics? How is the assay actually done? So the guy ejaculates in a cup, takes it to a lab? Oh, I mean, it used to be done manually. Okay.

And this is something that's standardized and automated through microfluidics? How is the assay actually done? So the guy ejaculates in a cup, takes it to a lab? Oh, I mean, it used to be done manually. Okay.

Yeah. Given how good AI is at image recognition, this should be a one-foot putt. Yeah. Okay. You mentioned hormones. You were obviously alluding to LH and FSH. What else are you looking at? Testosterone? Right.

Yeah. Given how good AI is at image recognition, this should be a one-foot putt. Yeah. Okay. You mentioned hormones. You were obviously alluding to LH and FSH. What else are you looking at? Testosterone? Right.

Sorry, these men are not making FSH and LH. No. So they have virtually no testosterone. Right. Nor sperm, but you can give them those signals. Yeah.

Sorry, these men are not making FSH and LH. No. So they have virtually no testosterone. Right. Nor sperm, but you can give them those signals. Yeah.

So is the problem in the pituitary, not the hypothalamus?

So is the problem in the pituitary, not the hypothalamus?

So could you give them Clomid and would they make?

So could you give them Clomid and would they make?

What about estradiol? Does it play a role?

What about estradiol? Does it play a role?

But if you correct for testosterone, so in other words, if a guy has normal FSH, LH, and testosterone, is there an estradiol level by itself that is problematic? Not usually. Okay. So it's really only high estradiol in the context of suppressed testosterone. Right. So that's when you would act on it.

But if you correct for testosterone, so in other words, if a guy has normal FSH, LH, and testosterone, is there an estradiol level by itself that is problematic? Not usually. Okay. So it's really only high estradiol in the context of suppressed testosterone. Right. So that's when you would act on it.

So those are four big pillars. Anything else besides the history, the exam, the analysis, and the hormones?

So those are four big pillars. Anything else besides the history, the exam, the analysis, and the hormones?

So never make a decision on one semen analysis. It's really hard. Yeah. Especially if it's the first one, as you said, for all the potential.

So never make a decision on one semen analysis. It's really hard. Yeah. Especially if it's the first one, as you said, for all the potential.

So what percentage of drugs that are going through an FDA approval process are having a semen analysis as part of the evaluation? I don't think many. Why is that? Because usually the indications aren't reproductive age men or women for some of them.

So what percentage of drugs that are going through an FDA approval process are having a semen analysis as part of the evaluation? I don't think many. Why is that? Because usually the indications aren't reproductive age men or women for some of them.