
Bird flu has been in the headlines for ages, with scientists warning that we could be headed for a pandemic. But we’ve been hearing about this H5N1 virus for so long that it’s kind of starting to feel like the boy who cried wolf. So — what’s really going on with H5N1 bird flu? How scary is it, and how likely is it that we’re going to end up in a bird flu pandemic? We talk to virologists Dr. Seema Lakdawala and Dr. Richard Webby. Find our transcript here: https://bit.ly/ScienceVsBirdFlu (00:00) Tons of people are freaked out about H5N1 bird flu (03:38) Why H5N1 bird flu is scary (05:01) Birds are falling out of the sky dead (07:32) Things get weird when bird flu gets into mammals (18:34) What happens when humans start getting this bird flu (23:26) Is bird flu mutating? (29:11) Should I worry about bird flu? (30:50) Do we have anything to fight bird flu? (32:14) We have had some silent cases of bird flu already This episode was produced by Blythe Terrell, with help from Wendy Zukerman, Michelle Dang, Rose Rimler, Meryl Horn and Ekedi Fausther-Keeys. We’re edited by Blythe Terrell with help from Wendy Zukerman. Mix and sound design by Bobby Lord and Sam Bair. Fact checking by Erica Akiko Howard. Music written by Bumi Hidaka, Peter Leonard, Emma Munger, So Wylie, and Bobby Lord. Thanks so much to all the researchers we spoke to for this episode, including Dr. Louise Moncla, Dr. Ted Elsasser, Dr. John Korslund, Victoria Rosado and Lindsey Adams. Thanks to Jeff DelViscio. Science Vs is a Spotify Studios Original. Listen for free on Spotify or wherever you get your podcasts. Follow us and tap the bell for episode notifications. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Chapter 1: Why is H5N1 bird flu considered a serious threat right now?
Hi, I'm Wendy Zuckerman and you're listening to Science Versus. Today on the show, we are pitting facts against bird flu. And to tell us all about it is editor of Science Versus, Blythe Terrell. Hey, Blythe. Yeah, hey, Wendy. So you've spent the last few months, I feel like, coming into meetings and saying, oh, my God, I just learned something crazy about bird flu. Oh, my God, Wendy.
And I have kept telling you to wait. for this conversation right here.
So... The day has finally come when I get to talk to you about bird flu.
The day has come. Tell me this crazy stuff you're hearing about bird flu.
Yes, I will. I will. And actually, Wendy, I will say it's been years that we've been talking about bird flu, not mere months.
It's true. It's true. I mean, when I think about it, the alarm bells about bird flu, just in general, becoming a global pandemic, I feel like they've been going on... and off and on again for like 20 years? I mean, to be honest, it is feeling a little boy who cried wolf at this point. I mean, has something changed?
Yeah, right. Yeah. What's different? What's different? That is an extremely fair question. I can say there are a few things that have kind of tipped things over the edge here. And for one thing, we have had like poultry farms being hit super, super hard.
So right now, the biggest outbreak of bird flu in U.S. history is sweeping across this country, leaving millions of hens dead.
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Chapter 2: How is the current bird flu outbreak affecting poultry and egg prices?
Since the outbreak started in 2022, the avian flu has impacted more than 135 million birds. We're hearing about these super high egg prices, you can't find eggs, which is partly because of bird flu.
Egg-flation is back with a vengeance, and it's cooking the family's grocery budget. Are they going up more? Are all the birds going to die?
Wendy, I have seen reports of eggs smuggling, like people getting busted bringing eggs across the border. Also, like, in New York City, in the Bronx, the bodegas are, like, selling egg loosies. Like, you know, you can usually buy, like, one cigarette at a time. They're selling, like, two eggs at a time.
In Australia too, eggs, crazy expensive right now. Supermarkets empty, kind of like the pandemic where the toilet paper used to be. Just like, it's kind of like that, but for eggs.
Yeah. And I mean, it is really like blowing up beyond chickens and eggs. So, you know, at this point they found the bird flu in like all sorts of animals, more than 450 species.
Recent tests show avian flu was detected in foxes, raccoons, skunks, and even domestic cats.
Many health experts are calling this a global pandemic of animals.
The UN has called the spread in animals, quote, unprecedented, actually. And then, yeah, like, all this is happening while the Trump administration is making cuts to science and to a bunch of the agencies that handle public health in the US. Right. So with all this going on, we are just getting this steady drumbeat of headlines and news reports saying that this bird flu is the real deal.
No more boy who cried wolf Wendy. It's only a matter of time before this thing could totally blow up and land us in another global pandemic.
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Chapter 3: What unusual symptoms and deaths are being seen in wild birds and mammals?
When we say we are in emergency mode, that is the mode we are in right now. Could potentially lead to another pandemic.
Oh, man. Are they right? That's what we're going to find out after the break.
Welcome back. Today we're talking about bird flu. Blythe is about to tell us if this is going to be the next pandemic.
Okay, yeah, so I want to start actually by talking about why exactly this bird flu scares the crap out of us so much.
Okay.
And a huge reason is that generally speaking, this type of bird flu, H5N1, can be really deadly for humans. Like, some of the warnings out there say that if we do get a bird flu pandemic, it could kill 100 million people. Why do they think that? Yeah, so there's a couple reasons, right? So, you know, if you look at past flu pandemics, like, often a lot of people get sick.
And this flu has a really high fatality rate. So when humans get this kind of bird flu, it tends to kill 50 to 60 percent of the people who get it. And, you know, with the caveat that there are some people who get bird flu and we don't know about, so maybe that death rate is a little high.
But still, I mean, over the past few decades, on and off, about 1,000 people have been diagnosed with this, H5N1, and about half of them have died.
Wow. And so how exactly are people dying from bird flu?
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Chapter 4: How does bird flu infect mammals and why does that worry scientists?
And so scientists are seeing all these awful deaths in birds, right?
And of course, what can happen with bird flu is that it moves with the birds who also move. So it makes its way to other countries, including the U.S. And we start seeing it in wild birds and in chickens. And this is like late 2021, 2022. And so in the U.S., what we do when this happens, when it shows up on like a poultry farm, whatever, we kill those birds. And we are killing millions of birds.
Which is definitely, like, one thing that can make eggs more expensive, right? You've got fewer birds, you've got fewer eggs. Right. So overall, as this happens, though, when it first kind of pops up, it's not ringing, like, huge alarm bells for humans, right? Like, it's crappy, but we're kind of used to bird flu and birds. Right.
But then this virus starts showing up in, like, more and more mammals. And scientists always keep an eye on that. Because... Once a virus starts like jumping species, maybe adapting to these different hosts, you start to worry that it could get to a point where it is easier for it to move from human to human.
Which at this point hasn't really happened.
Right. But here is SEMA. Every time a virus, like a bird virus, gets into a mammal, it can then adapt to that mammal, right? Because viruses change. We know this. COVID, right? Omicron, Delta. Like, you know, I'm saying things that people remember. Viruses change when they infect hosts.
Uh-huh. Okay.
So we're finding this new bird flu in all these different animals. But the important thing that happens next in our story is when it shows up in this particular mammal.
We've had sporadic spillover events from birds into seals in lots of different places, right? You might remember this. seal outbreaks.
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Chapter 5: Why is bird flu infection in cattle a game changer for the virus's spread?
And they actually had mastitis in their udders.
So this is where like the milk from a cow becomes like yogurt-y and yellow-y and chunky. And it's typically caused by bacteria.
Okay, so these veterinarians, they ran their tests. They did their thing. They were like, okay, is it this? Is it this? It doesn't seem to be any of these infections we thought it was. Right. And they were like pretty confused.
Yeah. And so then a veterinarian went on the farm and noticed some dead birds and a neurologically sick cat, like a cat with neurological symptoms.
Whoa. This is like house. This is like... Yeah. Like, right? It's super... Whoa. Detective work. Right. And then, of course, they work out that it's bird flu.
Mm-hmm. And the bird flu was giving the cat neurological symptoms and the cows mastitis.
Yeah, right, which is like kind of crazy. And what's interesting here is that they didn't just like pop a swab up the cow's nose and swirl it around in there. They also tested the milk.
And what they found was like massive amounts of virus in the milk. And when I talk about massive amounts, like it is scary how much virus is in the milk of a cow. And I'm talking 10 million to 100 million infectious particles in one milliliter. One milliliter of milk. Oh, gosh.
Was the virus alive? I mean, are we drinking that virus?
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Chapter 6: What are the risks of bird flu virus in cow milk and dairy products?
So this is also one of the most interesting things that I've learned.
Yeah. So to go back to one of the big concerns here, that we end up in a situation where the virus gets in more and more animals, more and more animals. Now that the cows have it, we think... a whole bunch of new animals might also be at risk.
Yeah.
And that's partly because of this disgusting and kind of fascinating thing called a manure lagoon. Oh, sounds like a 90s band.
You wish it were a 90s band, Wendy. And here's Seema. When a cow is sick, like say with H5 or with any bacterial infection, it has to be milked, right? It's inhumane to not milk a lactating cow. And so it is this like yogurt, chunkety milk, right? The smesitis milk. So it does not make it into our drinking milk.
It gets collected separately, and then it is poured into, typically on farms, into what's called a manure lagoon. Oh, no. And this manure lagoon is this large area where there's water, so there's always birds feeding at it. The milk is not treated, in most cases, before it is poured into the manure lagoon.
And again, just to remind you, like I said, 10 million to 100 million infectious virus particles per small milliliter. Wow. This is one of the ways we think that peridomestic animals on farms, near farms, are getting infected, right? Because it's just in the environment. Oh, no.
Don't. Don't put the milk in the manure lagoons. Oh, my gosh. So it's like it's just in the environment. It's just out there. Okay, so there's all this potential for humans to now get infected, not just from the cow to human interface, but also the cat-human interface and the rodent-human interface and the raccoon-human interface and the opossum. I'm sure those opossums are also getting it.
So where are we at now?
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Chapter 7: What is known about recent human infections with this new bird flu strain?
Right, right, yeah. We normally get it directly from a bird.
Okay.
And some people in the U.S. do start getting it from birds, too. So overall, in the past couple years, we've seen about 70 known cases of this bird flu in the U.S., of this H5N1 baby.
Uh-huh. 70 known cases. And so what's happening now when people get it? Are they getting really sick?
Yeah. So actually, this is what's pretty surprising. So despite all the scary headlines, every time someone gets bird flu, generally speaking, people who have gotten this in the U.S. are not getting that sick. Oh. We are mostly seeing people who have flu-y symptoms, your typical stuff, fatigue, respiratory issues.
We do see this one weird symptom that I want to talk about for a sec, cropping up a lot, because a lot of people are getting conjunctivitis or pink eye. Actually, one study looked at this, the people who'd gotten it, and found that 93% of them had gotten pink eye, which is like not typical for flu.
No, that is strange.
Yeah, but overall, like a lot of people are getting these sort of like milder symptoms.
Good news, great news there.
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Chapter 8: How likely is it that bird flu will cause the next human pandemic?
Yeah, there are vaccines. You can't just go get one at the pharmacy. They're not like available, but they do exist. Right. But as far as how they would do if bird flu really took off?
The good answer is we don't know really, right? Because we've never had a pandemic in humans. Yeah, we've never had a pandemic to know how good they are in humans, which is a good thing.
And we have stuff like antivirals that can help too.
It's funny because I have to go get my flu vaccine now because it's an early human flu season in Australia. But it did make me think that is this something that you can do?
Yeah. I mean, look, it's not going to do anything specifically for bird flu. They're just different enough. But you should do it. You should do it. I mean, a lot of scientists reminded me that the regular flu, Wendy, I mean, it kills thousands of people every year. Like that's still going on. Yeah.
And getting the flu vaccine does reduce the chance that, I mean, if you happen to be very unlucky, right, and also get bird flu, get that reassortment thing that we talked about, that you, Wendy, you know, will be patient zero of the bird flu pandemic. And actually, one of the things that Health and Human Services Department here in the U.S.
told me is that they are actually giving agricultural workers access to the seasonal flu vaccine as kind of part of their strategy here.
And so then just finally, what is the U.S. government saying about all this?
So, I mean, yeah, overall, like, bird flu does not really seem to be a big focus right now. You know, at the USDA, they are looking at ways to stop it in chickens. But like I mentioned at the start of the show, you know, the Trump administration is also like firing tons of people, including people whose job it was to work on diseases like this.
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