Habits and Hustle
Episode 440: The Hidden Benefits of GLP-1s: More Than Just Weight Loss Medication
Fri, 11 Apr 2025
Listen to the full episode here: https://podcasts.apple.com/us/podcast/habits-and-hustle/id1451897026?i=1000674829479 Are there hidden benefits to GLP-1s the FDA doesn’t want us to know? In this Fitness Friday episode on the Habits and Hustle Podcast, I speak with Dr. Tyna Moore who cuts through the misconceptions about GLP-1 medications. We explore the true nature of peptides beyond their popular use for weight loss. We also discuss why the current conversation around these medications has become unnecessarily polarized and vilified. Dr. Tyna is a leading expert in holistic regenerative medicine and resilient health with nearly three decades of experience in the medical world. As both a Licensed Naturopathic Physician and a Chiropractor, Dr. Tyna brings a unique perspective to building robust health foundations, having graduated from the National College of Natural Medicine and the University of Western States Chiropractic College. She is also a #1 Best Selling author, international speaker, and host of The Dr Tyna Show Podcast. What we discuss: What GLP-1s actually are (peptides vs. drugs) and how they work in the body The surprising research on GLP-1s' effects on neuroregeneration and inflammation How compounded versions allow for personalized microdosing The controversy surrounding pharmaceutical companies and compounding pharmacies Why these medications should be part of a comprehensive health protocol, not a standalone solution The background of peptide therapies in regenerative medicine and how they work How the FDA has recently restricted access to many peptide treatments Thank you to our sponsor: AquaTru: Get 20% off any purifier at aquatru.com with code HUSTLE Therasage: Head over to therasage.com and use code Be Bold for 15% off TruNiagen: Head over to truniagen.com and use code HUSTLE20 to get $20 off any purchase over $100. Magic Mind: Head over to www.magicmind.com/jen and use code Jen at checkout. BiOptimizers: Want to try Magnesium Breakthrough? Go to https://bioptimizers.com/jennifercohen and use promo code JC10 at checkout to save 10% off your purchase. Timeline Nutrition: Get 10% off your first order at timeline.com/cohen Air Doctor: Go to airdoctorpro.com and use promo code HUSTLE for up to $300 off and a 3-year warranty on air purifiers. Bio.me: Link to daily prebiotic fiber here, code Jennifer20 for 20% off. Momentous: Shop this link and use code Jen for 20% off To learn more about Dr. Tyna Moore: Ozempic Uncovered: https://www.drtyna.com/ozempicuncovered Instagram: https://www.instagram.com/drtyna/ Youtube: https://youtube.com/@drtyna Find more from Jen: Website: https://www.jennifercohen.com/ Instagram: @therealjencohen Books: https://www.jennifercohen.com/books Speaking: https://www.jennifercohen.com/speaking-engagements
Chapter 1: What are GLP-1s and how do they function in the body?
Let's start with what GLP-1 is. It's a peptide. So it's a string of amino acids linked together by peptide bonds. So it's a peptide. We make GLP-1 in our bodies naturally in our brain and in our guts. We have receptors for GLP-1s all over our body that do a whole lot of different things. It just was serendipitous that it got figured out for type 2 diabetes.
It does a whole lot of other things in the body. And this was really interesting to me when I started studying it. It's a peptide in that it's in and out of the body very quickly. So the body produces it and the half-life is very short. The pharmaceutical version has been tinkered with so that the half-life is much longer. So the half-life is maybe four to seven days. So that's it.
It's bioidentical. At least Ozempic, which is semaclutide, is bioidentical to our own GLP-1 for the most part. And about a year ago, I started finding literature outside of what most people understand it for. Most people understand it for reducing appetite because it plays on the centers of our brain that control appetite, for slowing gut motility so you feel fuller longer.
And that's kind of where the story ends. That's kind of where people understood how it works. And that's why it's a weight loss drug. And that's why it's for type 2 diabetes. It has multiple impacts on our metabolic health in a myriad of ways that have a lot more to do than just that. And there are receptors in our brains, in our heart, in our pancreas, in our immune cells.
Chapter 2: What are the potential health benefits of GLP-1s beyond weight loss?
And I started finding literature that was really, really interesting about this, and I started going on podcasts and sharing about it and finding information. Recent studies have come out showing significant reduction in all-cause mortality for those who are on it, reduction in different types of cancers. Cancers?
colon cancer specifically, this was correlative, not causative, but they were comparing people on semaclutide versus, or even some of the other GLP-1s for a period of time versus, I think, insulin. And not a great, I mean, it's not a super clear comparison because insulin is pro-grow, so insulin can cause problems in and of itself.
But interesting data coming out there recently, 13 different types of, potentially reducing 13 different types of obesity-related cancers in And then I was finding data and sharing out about potential protection against COVID and upper respiratory illness. And I was sharing about it on podcast thinking, well, if anything, I'm helping big pharma sell their peptides.
Chapter 3: Why is there controversy surrounding the use of GLP-1 medications?
So they'll probably leave me alone. Like I didn't think I was a threat there, you know? And honestly, the microdose is completely independent to the individual sitting in front of me. And that person, for that person, it might be the standard starting dose. Like that might be their microdose, right? So I have no idea. Yeah.
But then I started a second account a few days later, and it grew to 15,000 followers pretty quickly, and it was shut down within 36 hours. And that's when I realized, like, oh, somebody wants me to shut up.
Right, right, right. Well, I mean, if you're trying to take business away, who makes Ozempic? Who's the company that makes Ozempic?
Novo Nordisk, and then Monjoro is Terzepatide, and that's Eli Lilly. But I mean, I have no interest in... keeping people away from the standard. I don't care.
What's interesting is when I started talking about this, I was like, you guys, I'm finding all this amazing literature supporting GLP-1s for neuroregeneration and decreases in inflammation and neural inflammation, which I think is really cool. That's where I got most interested. And potential, there's studies being done right now on potential improvements in Alzheimer's and Parkinson's.
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Chapter 4: How do personalized microdoses of GLP-1s work?
And like, this is super exciting, guys. And my followers, so many of them turned on me and they're like, when did you get bought out by Big Pharma? When did you become a Big Pharma shill? So they're screaming at me in my comment section, accusing me of being a Big Pharma shill. And I'm like, no, I'm talking about compounded versions, you guys. I'm not even talking about the standard brand name.
But if you want to use the standard, great. And many of the people that I talked to in my following have said, you know, I could only get a hold of the standard brand. brand name, through my regular doctor, through regular pharmacy, and it's changed my life. So I'm like, cool. You know, I don't have any favoritism either way.
I'm just saying that if for someone like you, as lean as you are and metabolically optimized as you are, if you had maybe cardiovascular disease in your family or you were dealing with some kind of neurodegenerative condition, we would need tiny, tiny doses for you.
So wait, like, so, so yeah, that's what's interesting. So in your opinion, should everybody be on one of these GLP-1, like an anoxempic form for their metabolic health?
I think I get asked that a lot. I think that's kind of a bold statement to make. And I wouldn't say yes to that. I think the way that I've always practiced medicine is I'm just trying to treat the person in front of me. And I'm trying, I don't use this in isolation. It's not a monotherapy. It's part of a comprehensive protocol. So I'm a big fan of bioidentical hormone replacement.
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Chapter 5: What are the implications of GLP-1s on neurological health?
I've been using it in practice for a long time. My background was actually as a regenerative medicine doctor. So I was doing prolotherapy, PRP, stem cells, exosomes, regenerative therapies in my clinic for decades. So to me, peptides are just part of that. And this is just another peptide.
But where do peptides even come from? I feel like the word peptide has become very popular, very trendy only in the last few years. Like before, like five years ago, I never even heard of a peptide. Most of my friends never heard of a peptide. And then in the last four or five years, there's lots of peptides that people are taking, the BPC-157, the CJC-1290, whatever it is for peptides.
There's so many. And I think, number one, it's inconclusive from what I've heard. And so people don't, there's not much, but most people don't know much about them. And so it's scary. And I don't even think people that mass, and I only say that for people who are in my world, who are in the health and wellness space or longevity space or the fitness space.
Chapter 6: How has the FDA's regulation affected access to peptide treatments?
If I'm like confused, I can only imagine how people who are just layman's like, you know, an accountant working at a
You know what I mean?
Or someone in the marketing department at like Hasbro.
Yeah.
You know what I mean? Like, what, like, how do you even, like, I feel like, can you start from the beginning? Like, where did it even, how did it become even something that was even to be taken for optimizing your health or for your longevity? Yeah.
Well, these started popping up in the regenerative medicine space, at least in my, you know, when I caught wind of them, I would say 2017, 2018. And we use them short term and we use them, we cycle them. So say you injured your shoulder. Right. We put you on a stack of peptides to optimize your shoulder. I would probably do some regenerative injections.
You can even inject these locally to the injured area. Like stem cells. Yeah, you could do however you want. They seem quite safe. They're strings of amino acids, and they insert themselves in. Many of them have anti-inflammatory properties. Many of them have regenerative properties. And when I say regenerative, I think people get confused. It's not like...
We're going to drop some BPC-157 on a heart cell in a Petri dish or some GLP-1, and it's going to make new heart cells. What I mean when I say regenerative in the regenerative medicine world is that often we're just abating pathology. So when you hurt yourself, there's a whole downstream... process of cytokines and inflammatory molecules that happen as the body's trying to heal itself.
And sometimes the body gets caught in a loop. So a herniated disc is a great example. The nucleus pulposa will squish out of the disc and it's called the annulus, the protective coating of the intervertebral disc. And it's not supposed to be on the outside. And once it's on the outside, the body freaks out and sends in everything. And that's why the initial injury hurts.
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