Menu
Sign In Search Podcasts Charts Entities Add Podcast API Pricing

Molly Webster (host)

πŸ‘€ Person
185 appearances

Podcast Appearances

Radiolab
The Spark of Life

Wait, wait, am I glowing right now?

Radiolab
The Spark of Life

Hey, this is Radiolab.

Radiolab
The Spark of Life

I'm Molly Webster.

Radiolab
The Spark of Life

So I was a bio major and we had to take maybe one physics class and then we never thought about it again.

Radiolab
The Spark of Life

And this is often how it goes in the sciences.

Radiolab
The Spark of Life

You've got biology.

Radiolab
The Spark of Life

The environment, animals, our bodies, the kind of organic, messy physical stuff, that's on one side.

Radiolab
The Spark of Life

And then you have physics, all the abstract stuff, waves, energy, invisible particles, that's all on the other side.

Radiolab
The Spark of Life

They very much feel like two different worlds.

Radiolab
The Spark of Life

Can I ask you a couple questions before we get started?

Radiolab
The Spark of Life

You can ask me so many questions.

Radiolab
The Spark of Life

But for Narosha Murugan, they go hand in hand.

Radiolab
The Spark of Life

What I learned from talking to Narosha and what you're going to hear in our conversation today, it is definitely a leap into the unknown.

Radiolab
The Spark of Life

But it starts with a very simple idea about how living thingsβ€”bacteria, cactuses, humans, whateverβ€”

Radiolab
The Spark of Life

how they do what they do.

Radiolab
The Spark of Life

And it's an idea that made me think about the kind of mark we leave on the world.

Radiolab
The Spark of Life

So we're going to start with Narosha as a student.

Radiolab
The Spark of Life

Norosha says she was standing there thinking about all the little molecules in her skin and nerves and spine, all these proteins bumping into each other, interacting and passing along a signal, burn, ow, until it reached her spine.

Radiolab
The Spark of Life

And then a signal goes back, more proteins bumping into each other, interacting, signaling, move, move your hand, move your hand, back down her arm, all in a split second.

Radiolab
The Spark of Life

Yeah, there's this shorthand that we use for talking about biology, which is that a lock and a key go together and that like makes things happen in the cell.

Radiolab
The Spark of Life

So something is a shape and it fits into a hole.

Radiolab
The Spark of Life

I'm like, wow, this is why you were a better bio student than I was.

Radiolab
The Spark of Life

Because I was like...

Radiolab
The Spark of Life

I don't know.

Radiolab
The Spark of Life

There's a lock.

Radiolab
The Spark of Life

There's a key.

Radiolab
The Spark of Life

Like one of them is the lock shape.

Radiolab
The Spark of Life

One of them is the key shape.

Radiolab
The Spark of Life

The key goes into the lock.

Radiolab
The Spark of Life

It's just floating along.

Radiolab
The Spark of Life

Yeah, and with also, if you think about like the interior of a cell, it's like there's thousands of other proteins and there's, you know, trash and there's the nucleus and there's, I don't know, endoplasmic reticulum.

Radiolab
The Spark of Life

There's like all sorts of things inside the cell that are between the lock and the key, between the two shapes like finding each other.

Radiolab
The Spark of Life

Damn, it's pretty fast.

Radiolab
The Spark of Life

It's like the janitor took the ring of keys and just threw it at a lock and somehow the right key on that ring disappeared.

Radiolab
The Spark of Life

Gets into the lock and like it makes it across the space, even though there's so, so much in the middle.

Radiolab
The Spark of Life

As Narosha kept puzzling this, she thought maybe there's something in physics, the world where particles are always zipping around really fast, maybe there's something there that could help me out.

Radiolab
The Spark of Life

What Narosha stumbled into was a weird little corner of biology pioneered by this Russian biologist, Alexander Gurvich.

Radiolab
The Spark of Life

In the 1920s, he did a series of experiments on onion roots to understand how they grow.

Radiolab
The Spark of Life

And I'm gonna be real with you, the original papers in Russian, it was kind of a crazily complicated experimental setup.

Radiolab
The Spark of Life

But basically in the process of doing these experiments,

Radiolab
The Spark of Life

He made a discovery that seemed to suggest that the onion cells inside the roots were making and releasing their own light.

Radiolab
The Spark of Life

So not only am I emitting light or cells are emitting light, they could be emitting light of different color.

Radiolab
The Spark of Life

Wait a second.

Radiolab
The Spark of Life

So when my friends try and like drag me down to get my aura red, is that this?

Radiolab
The Spark of Life

Okay, so if I'm a cell and I'm giving off light and maybe we have to pick a specific cell, I don't know.

Radiolab
The Spark of Life

How does that actually work?

Radiolab
The Spark of Life

So you probably know this.

Radiolab
The Spark of Life

One of the structures inside the cell is the mitochondria.

Radiolab
The Spark of Life

It looks like a microscopic kidney bean with tiny little folds inside of it.

Radiolab
The Spark of Life

And it is often called the powerhouse of the cell.

Radiolab
The Spark of Life

Hey, internet.

Radiolab
The Spark of Life

It creates all of the energy that makes us run.

Radiolab
The Spark of Life

So that's neurons firing, muscles contracting, bodies working.

Radiolab
The Spark of Life

It all comes from the mitochondria.

Radiolab
The Spark of Life

And the way that works is molecules will pass electrons back and forth to each other all along the inner folds.

Radiolab
The Spark of Life

And that process of passing releases energy.

Radiolab
The Spark of Life

Is like a high energy electron like a kid with a lot of sugar and then like a low energy electron is like when they come down off the sugar?

Radiolab
The Spark of Life

Dad, this part is like the juicy part.

Radiolab
The Spark of Life

So you're saying that, I don't know, we're giving off life because we're doing fun things with our electrons.

Radiolab
The Spark of Life

Because we're alive.

Radiolab
The Spark of Life

We're because, yeah.

Radiolab
The Spark of Life

There are a number of different ideas about where light could be coming from inside the cell.

Radiolab
The Spark of Life

It could be these electrons.

Radiolab
The Spark of Life

It could be a buildup and release of charged particles.

Radiolab
The Spark of Life

It could be something having to do with fatty acids.

Radiolab
The Spark of Life

It could be a combination of things.

Radiolab
The Spark of Life

For Narosha, she's finding that when she interrupts that electron chain, the light changes.

Radiolab
The Spark of Life

Do you have a sense of how many photons a cell is emitting at any moment?

Radiolab
The Spark of Life

About a million.

Radiolab
The Spark of Life

So say a million brain cells emitting 100 photons a second as a group.

Radiolab
The Spark of Life

I got really lost in an image of like the mitochondria just releasing like fireworks all the time.

Radiolab
The Spark of Life

Like I was like, oh, these little cells are popping off.

Radiolab
The Spark of Life

It's like after a baseball game on the 4th of July.

Radiolab
The Spark of Life

Yeah, that's probably accurate.

Radiolab
The Spark of Life

And is it that light that I might potentially be seeing if I had an amazingly dark space?

Radiolab
The Spark of Life

That's exactly it.

Radiolab
The Spark of Life

I wonder if some of it is like people have been like, that's bullshit.

Radiolab
The Spark of Life

Because it's like we've already talked about auras.

Radiolab
The Spark of Life

I can imagine like a lot of folks being like, no, this isn't legit.

Radiolab
The Spark of Life

Sensing organ.

Radiolab
The Spark of Life

Light-sensing organ.

Radiolab
The Spark of Life

And so it senses light.

Radiolab
The Spark of Life

But that's where my light interaction shuts down.

Radiolab
The Spark of Life

And it sounds like you're saying there's more light interactions happening.

Radiolab
The Spark of Life

Wait, is that the only direct interaction I have with the wavelengths from the sun that I'm like actively converting?

Radiolab
The Spark of Life

We as creatures have evolved with the sun for so long that there are many, many elements of our cells that are able to absorb light.

Radiolab
The Spark of Life

And so now the question is, if that's the case, could the light coming from inside of our cells also be absorbed?

Radiolab
The Spark of Life

Could it be used purposefully to trigger some processes in us?

Radiolab
The Spark of Life

So we really are in a lot of like theoretical ideas.

Radiolab
The Spark of Life

Like once we get beyond the revelation, which will be a revelation to a lot of people that

Radiolab
The Spark of Life

biological material cells, me, you, are emitting light, then a lot of the questions that come after that of like how, why, when.

Radiolab
The Spark of Life

What does it mean?

Radiolab
The Spark of Life

What does it mean?

Radiolab
The Spark of Life

Coming up, Narosha tries to find out what the light inside our bodies might be doing.

Radiolab
The Spark of Life

Like, what are those little photons up to?

Radiolab
The Spark of Life

The cellular fireworks continue after the break.

Radiolab
The Spark of Life

Hey, I'm Molly Webster.

Radiolab
The Spark of Life

We're stepping into a world of questions.

Radiolab
The Spark of Life

And one of the first ones Narosha wants to tackle is how what seems like a cellular firework show might actually be more like a laser or something.

Radiolab
The Spark of Life

Like if there's a purpose to the light and it's directed, it's a sentinel of information, like, I don't know, isn't it a photon?

Radiolab
The Spark of Life

Don't they just flow through things when it just like flows?

Radiolab
The Spark of Life

So every cell is filled with individual little tubules.

Radiolab
The Spark of Life

that are help giving it its shape, little rods.

Radiolab
The Spark of Life

And your question was, do those things suck up some of the light?

Radiolab
The Spark of Life

There's a little tram system that's inside the cell.

Radiolab
The Spark of Life

Okay, but do you have any proof thus far that that light is not just being cast off like fireworks into the cellular night, that it is actually being moved from an A to a B?

Radiolab
The Spark of Life

So when there's activity in the brain, there's light in the brain.

Radiolab
The Spark of Life

That's correct.

Radiolab
The Spark of Life

I mean, do you have any hypotheses of like what information light might be carrying inside the brain?

Radiolab
The Spark of Life

There's honestly so much about this world of light inside the body that we don't know yet.

Radiolab
The Spark of Life

Some of the researchers describe this field as risky, like it could all add up to nothing.

Radiolab
The Spark of Life

But if they're right, it could change everything, or at least a lot of things.

Radiolab
The Spark of Life

For Narosha, even if she doesn't know what the purpose of the light is inside the body, like even if there isn't one, it might have a purpose for us outside the body.

Radiolab
The Spark of Life

To say, oh, hey, your body's growing cancer.

Radiolab
The Spark of Life

I guess the question then is, is there a significant difference between the photon release in cancer cells versus other cells?

Radiolab
The Spark of Life

And we've shown that and we've published that.

Radiolab
The Spark of Life

They have two different light signatures.

Radiolab
The Spark of Life

So with the light coming off cancer, you guys are actually diagnosing cancer earlier?

Radiolab
The Spark of Life

So even if it's like, even if the light was not biologically purposeful, you're thinking maybe it could still be diagnostically useful.

Radiolab
The Spark of Life

So it's like basically we've walked through...

Radiolab
The Spark of Life

I'm just gonna make you say it again, but you've like walked through brain cells that let out photons, tumor cells that let out photons, normal body cells that let out photons.

Radiolab
The Spark of Life

You're saying everybody, every cell that you've looked at

Radiolab
The Spark of Life

When does the light start?

Radiolab
The Spark of Life

And then does it truly go away?

Radiolab
The Spark of Life

Like a surgeon's just saying just for the purpose of surgery where we stop a heart and start a heart, there's like an electric explosion of light?

Radiolab
The Spark of Life

I don't have the scientific evidence for this, but... No, yeah, you clearly... Yeah, but I'm just saying, like, what my... I don't know how to solve that at all.

Radiolab
The Spark of Life

The energy has to go somewhere.

Radiolab
The Spark of Life

So it just is released.

Radiolab
The Spark of Life

It is the fireworks that I've been talking about.

Radiolab
The Spark of Life

Do we have any idea of when...

Radiolab
The Spark of Life

like the light first turns on?

Radiolab
The Spark of Life

I'm getting so excited.

Radiolab
The Spark of Life

Watch fireworks explode when a human egg is fertilized.

Radiolab
The Spark of Life

I'm hitting play.

Radiolab
The Spark of Life

It's stat news, so I believe it.

Radiolab
The Spark of Life

It is like an... There's like a round egg, and then the sperm is at the edge.

Radiolab
The Spark of Life

And then you just see kind of this explosion come off the surface.

Radiolab
The Spark of Life

A flash, yeah.

Radiolab
The Spark of Life

I mean, it is really crazy, because literally after we have this conversation, I'm going down to South Carolina, where my dad is in hospice, like near the end of his life.

Radiolab
The Spark of Life

you do have all these questions about just like what's happening, what's unfolding, like a notion that, I mean, I'm sure I'm not going to see like a flash of light happen.

Radiolab
The Spark of Life

I mean, I'll keep my eyes peeled, but you know, just like the notion of like a signal out into the world, like that's so

Radiolab
The Spark of Life

visual even if we can't really see it but like light is so meaningful to us you know that it could that like it is a signature of of us and that that it's like a final salute or something you're letting the energy that was patterned into this architecture that we are out back to be transformed into something else

Radiolab
The Spark of Life

Yeah, it's like it is.

Radiolab
The Spark of Life

Yeah, it's really pretty.

Radiolab
The Spark of Life

Thank you to Narosha Murugan.

Radiolab
The Spark of Life

You can find her at Wilfrid Laurier University in Canada.

Radiolab
The Spark of Life

This episode was produced by Sara Khari with help from me.

Radiolab
The Spark of Life

It was fact-checked by Natalie Middleton.

Radiolab
The Spark of Life

For those of you who are gonna go check out that life flash video, one thing to note, you're gonna see a big flash of light in the video.

Radiolab
The Spark of Life

That is not the biophotons.

Radiolab
The Spark of Life

That is a fluorescent dye that researchers added to the experiment so they could see it better.

Radiolab
The Spark of Life

But beneath that dye, the thing that it's very much illuminating is a very quiet, gentle light.

Radiolab
The Spark of Life

And I'd like to dedicate this episode to my dad.

Radiolab
The Spark of Life

I did not see a flash of light, but I certainly felt one.

Radiolab
The Spark of Life

I'm going to miss you, Pops.

Radiolab
The Spark of Life

Thanks for always listening.

Radiolab
The Spark of Life

This is Radiolab.

Radiolab
The Spark of Life

We will be back next week.