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Dr. Peter Attia

👤 Person
11178 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So even if they were taking some hit off the bike, it was probably more than compensated for by their healthy lifestyle, which included probably riding the bike. But obviously there's a healthy user bias because anybody who's riding their bike to work is probably consuming less Guinness, fewer fish and chips, smoking less.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So even if they were taking some hit off the bike, it was probably more than compensated for by their healthy lifestyle, which included probably riding the bike. But obviously there's a healthy user bias because anybody who's riding their bike to work is probably consuming less Guinness, fewer fish and chips, smoking less.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

In other words, riding a bike is a proxy for being healthy, but in spite of that, it didn't offset that health risk, unless we found people who were equally healthy who didn't ride a bike.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

In other words, riding a bike is a proxy for being healthy, but in spite of that, it didn't offset that health risk, unless we found people who were equally healthy who didn't ride a bike.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

That's because it's a leather saddle and it fit to you. Yeah. Iconic. Okay, let's talk about alcohol specifically, and let's talk about any other recreational drugs.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

That's because it's a leather saddle and it fit to you. Yeah. Iconic. Okay, let's talk about alcohol specifically, and let's talk about any other recreational drugs.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Any evidence that it's having an epigenetic effect? Probably. I don't know about evidence, but I'm sure it does. Let's talk about common recreational drugs. Let's start with marijuana.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Any evidence that it's having an epigenetic effect? Probably. I don't know about evidence, but I'm sure it does. Let's talk about common recreational drugs. Let's start with marijuana.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And we think that that's causal? I don't know. It just worries me. Weed worries me. Interesting, given that it otherwise seems kind of benign. I personally can't stand this stuff, but I know so many people that use it so frequently that seem to have relatively few effects.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And we think that that's causal? I don't know. It just worries me. Weed worries me. Interesting, given that it otherwise seems kind of benign. I personally can't stand this stuff, but I know so many people that use it so frequently that seem to have relatively few effects.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

I'm not saying that one is driving stoned is good, but there are probably far fewer people that die at the hands of a stoned driver than a drunk driver. Probably.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

I'm not saying that one is driving stoned is good, but there are probably far fewer people that die at the hands of a stoned driver than a drunk driver. Probably.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

What do you think is the mechanism of action by which THC is having these negative fertility impacts? Not sure. I don't think it's the mechanism.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

What do you think is the mechanism of action by which THC is having these negative fertility impacts? Not sure. I don't think it's the mechanism.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So you can get low testosterone, but it's not been that profound. What about nicotine, either synthetically or in the form of tobacco? Bad actor at high doses, I think, too. Either one? Yep.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So you can get low testosterone, but it's not been that profound. What about nicotine, either synthetically or in the form of tobacco? Bad actor at high doses, I think, too. Either one? Yep.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

It's the oxidants that do it. It's oxidizing things. You mentioned diabetes earlier as part of your history and physical. What is it about diabetes? Is it the high levels of glucose? Is it the microvascular damage? Is it the inflammation that typically travels in parallel with it? Why is type 2 diabetes a risk factor for infertility?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

It's the oxidants that do it. It's oxidizing things. You mentioned diabetes earlier as part of your history and physical. What is it about diabetes? Is it the high levels of glucose? Is it the microvascular damage? Is it the inflammation that typically travels in parallel with it? Why is type 2 diabetes a risk factor for infertility?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

What's the physical finding you're seeing in the testes that tells you, like, you know how an ophthalmologist will often make the diagnosis because they're looking into the eye?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

What's the physical finding you're seeing in the testes that tells you, like, you know how an ophthalmologist will often make the diagnosis because they're looking into the eye?