Dr. Paul Waytz
👤 PersonAppearances Over Time
Podcast Appearances
Okay. So lupus is an autoimmune disease that generally affects women 10 times more than men. So you're correct there. And like with rheumatoid arthritis that primarily involves the joints, you can get joint involvement with lupus, but generally speaking, you have other organ systems involved, such as the skin. The lining of the lungs, the lining of the heart. So you have multiple symptoms.
Okay. So lupus is an autoimmune disease that generally affects women 10 times more than men. So you're correct there. And like with rheumatoid arthritis that primarily involves the joints, you can get joint involvement with lupus, but generally speaking, you have other organ systems involved, such as the skin. The lining of the lungs, the lining of the heart. So you have multiple symptoms.
You have joint pain. You have chest pain. You have shortness of breath. The bad thing with lupus, the really bad thing, is I think the statistics are, let's just say, a good proportion, over 50%, will have kidney problems. That the inflammation attacks the kidney, which causes kidney failure.
You have joint pain. You have chest pain. You have shortness of breath. The bad thing with lupus, the really bad thing, is I think the statistics are, let's just say, a good proportion, over 50%, will have kidney problems. That the inflammation attacks the kidney, which causes kidney failure.
And there are several different kinds of kidney failure such that you really need to recognize what's going on. So part of a lupus evaluation includes looking at a urine specimen and doing blood tests that look at kidney function. Lupus can affect the brain. It can affect not only the lining of the heart, but the heart itself. It can affect other blood vessels.
And there are several different kinds of kidney failure such that you really need to recognize what's going on. So part of a lupus evaluation includes looking at a urine specimen and doing blood tests that look at kidney function. Lupus can affect the brain. It can affect not only the lining of the heart, but the heart itself. It can affect other blood vessels.
So it is potentially a life-threatening disease. Whereas rheumatoid arthritis tends to not be life-threatening, but chronic in pain, you can have life-threatening issues. And just like rheumatoid arthritis, it's a disease of young people, especially young women, women between the ages of 20 and 40. Wow. Wow. Wow. So, all right.
So it is potentially a life-threatening disease. Whereas rheumatoid arthritis tends to not be life-threatening, but chronic in pain, you can have life-threatening issues. And just like rheumatoid arthritis, it's a disease of young people, especially young women, women between the ages of 20 and 40. Wow. Wow. Wow. So, all right.
Yeah, yeah. The yes, overuse can certainly lead to more wear and tear arthritis. And again, it's about the idea of pounding that cartilage in the knee or hips or shoulders with people, whatever they're doing, torquing or lifting weights and this type of thing that you're putting an unusual amount of force into. Cartilage is made to absorb a certain amount of force.
Yeah, yeah. The yes, overuse can certainly lead to more wear and tear arthritis. And again, it's about the idea of pounding that cartilage in the knee or hips or shoulders with people, whatever they're doing, torquing or lifting weights and this type of thing that you're putting an unusual amount of force into. Cartilage is made to absorb a certain amount of force.
If you overdo it for too long, then that's going to create some problem there. So that nice cushioning of the cart that the cartilage provides falters. And then it sets off, you know, a process that then includes inflammation that just aggravates the process. Now people said, well, does running or does running cause or not cause arthritis of the knees?
If you overdo it for too long, then that's going to create some problem there. So that nice cushioning of the cart that the cartilage provides falters. And then it sets off, you know, a process that then includes inflammation that just aggravates the process. Now people said, well, does running or does running cause or not cause arthritis of the knees?
And there have been studies that looked at marathon runners over years. And early studies suggested that it doesn't, that running doesn't, you know, marathon running. Now, you have to factor in a couple of things. You have to really look at more than a few years after as time goes on, so maybe 10, 15, 20 years. And that data still doesn't exist in clear fashion yet.
And there have been studies that looked at marathon runners over years. And early studies suggested that it doesn't, that running doesn't, you know, marathon running. Now, you have to factor in a couple of things. You have to really look at more than a few years after as time goes on, so maybe 10, 15, 20 years. And that data still doesn't exist in clear fashion yet.
The other thing is marathon runners tend to be very athletic, so they're not overweight and they're taking good care of themselves and they're eating properly, this type of thing. So it can be multifactorial. The other thing is that a prior injury someplace, so say you, I don't know, fell down some stairs when you were a kid and you had a bad knee, that is a precursor
The other thing is marathon runners tend to be very athletic, so they're not overweight and they're taking good care of themselves and they're eating properly, this type of thing. So it can be multifactorial. The other thing is that a prior injury someplace, so say you, I don't know, fell down some stairs when you were a kid and you had a bad knee, that is a precursor
to running, aggravating the knee problem. So if there's something underlying going on, then you're gonna have issues. So overuse can certainly lead to wear and tear arthritis, but we're talking decades down the line, we're talking decades. Now, let me just, you know, I love stories. There were autopsy studies of Korean War casualties.
to running, aggravating the knee problem. So if there's something underlying going on, then you're gonna have issues. So overuse can certainly lead to wear and tear arthritis, but we're talking decades down the line, we're talking decades. Now, let me just, you know, I love stories. There were autopsy studies of Korean War casualties.