Alex Tarnava
Appearances
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Our last universal common ancestor, the single cell organism that spawned all life on this planet, actually consumed hydrogen as its fuel source.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
We quickly realized that doing this in mass, making millions of tablets at high speed is dramatically different for safety, for getting the reaction right, everything, than making 20 in a mortar and pestle, mixing by hand and then hand pressing. It took us a year to... over 2,000 iterative adjustments, and 15 failed scale-up attempts at manufacturing to get our first production-ready tablet. Wow.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Since then, we've stopped counting at version 5,000. Right. But we're probably at 10,000 iterative adjustments in the R&D process to get to where we are.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
the water and get in in this open cup and get these small nano bubbles in the 10 to 30 nanometer in range which is critically important so that in in say half a liter of water or 16.8 ounces we're getting over 12 parts per million that's incredible i mean that's really incredible and i think a lot of people uh you know when i talk about hydrogen gas in the water they're
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And I know I told you we have a couple of clinical trials head to head against caffeine after acute sleep deprivation. So in the first study, we showed equivalent improvement in the attention network test to caffeine, but they affected different domains of attention. Caffeine affects alerting, and the hydrogen affected orienting.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So we did a bigger, better controlled study with four groups, and it was a crossover design also. So everyone did all therapies. So it was a quadruple crossover, so a crazy design. So there was placebo-placebo, hydrogen-placebo, caffeine-placebo, and caffeine plus hydrogen. And it found that...
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
The hydrogen groups with or without caffeine had a substantially more robust improvement in brain metabolism. So choline to creatine ratios in the brain than the caffeine alone. So hydrogen was basically it's as your brain metabolism slows due to the acute stress of sleep deprivation. Hydrogen is temporarily restoring it back to proper function.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Well, that's linked to young blood. So anyone who's seen the research where they take an aged mouse and they take the blood of a young mouse and, you know, swap it out like an oil change and it revitalizes the old mouse, their skeletal tissue anyways, that's linked to TET2.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Was it actually in that study? Uh, so that's, uh, you can bring it in. Like research is, is very important to me when I decided to go down this road. Um, as we all know, there's so many snake oil salesmen in the health industry and supplements.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And I wanted to do something that I could look at myself in the mirror and go to bed happy and feel like I'm having a purpose in life and I'm doing something good, not just out there to make money. Right. Right. So, uh, As we were getting ready to launch, I did a bunch of research on what the regulatory requirements are. So we have grass status and new dietary ingredient status with the FDA.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Actually, now we have 21 validated structure function claims to FTC standards through an expert panel that reviewed all our research. But I wanted to make sure that my hunch that the higher concentration and dose we were delivering was actually going to have an effect and wasn't going to have a harm. Because that's... very important with any molecule.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Every molecule works on a dose dependent and sometimes concentration dependent response. And increasing the dose can increase efficacy, but there could be side effects. And I really wanted to explore this to make sure I was delivering something that was safe and effective for people.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So before we launched, as we were doing our first production run, I emailed every single first and corresponding author on every single clinical trial on hydrogen and preclinical in mice. And I offered free product, free placebo, and to donate funds, no questions asked. So I don't believe in silencing science.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
We cannot understand this world better if we're not publishing negative data. Wow. As we've talked about before, the big problem there is a law passed in the 1920s called shareholder supremacy. So corporations have to do what's best for their shareholders. And if they don't, they're breaking the law and can be sued.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So that's why I've kept my company private so that I can make my own decisions and be like, this is what is true and ethical and moral.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
right this is how I'm gonna do and that's why I've resisted all you know venture capitalists who have tried to invest right in my companies so I got some bites and that's why now just in the last six seven years since we've been doing research we actually have more clinical and preclinical research than all other commercial hydrogen water products combined Wow right so
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And we have way more that's, you know, we have like over 20 human studies now.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And we can actually even talk about it from the very beginning, why it's important from evolution and why we're not getting it. Yeah, let's do that. So... What we're realizing is, first, we realize that hydrogen is having this impact on the body, right? Then the question is, what's the mechanism? How is it having this impact?
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And we've now been able to identify there's a few different mechanisms that's working. Throughout the whole body, it's acting as something called the mitohormetic effector. So that's hormesis of the mitochondria. So hormesis is anything like a stress that's mild enough that we get stronger from and adapt. So exercise, cold exposure, sauna. Sunlight.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Even radiation in certain amounts, like sunlight. even ethanol at the right dose, right? And timing. It's just with hormetic agents, they all operate on like a reverse U or a reverse J. When you don't get it at all, you start here. If you get the right dose and timing, you improve your health. And then if you go too high, it goes either back to baseline or a lot worse.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Like with alcohol, it's a very tight reverse J, which is why we can't really recommend alcohol for anyone at any dose because... every person would find a benefit at a different dose and every day. So we just don't have the science there to make advice. But so we're acting kind of like exercise for the mitochondria, which is improving the health and the number of the mitochondria.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
In addition, hydrogen is interacting with our microbiome, it's improving gut health. And in a yet to be fully understood mechanism, we know we're partially metabolizing it in the liver, and it's driving liver homeostasis. So there's a few ways that hydrogen is helping. And now why is hydrogen doing this in our body? What role did it have? We actually have to go back to the
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
very beginning of evolution. So our last universal common ancestor, the single-cell organism that spawned all life on this planet, actually consumed hydrogen as its fuel source, right? And then our first mitochondria came from eukaryotes. And those eukaryotes was a symbiotic relationship between organelle, one of which... expelled hydrogen as a waste product.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And now we've actually carried that throughout all of evolution. And there's other factors, too. At times in evolution, a couple billion years ago, there was a lot more hydrogen in the air and water.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Molecular hydrogen is the first molecule in the universe, too, right? So it seems obvious in retrospect that it has a role In our life and our body. And we actually, we evolved to produce a tremendous amount of hydrogen gas internally, endogenously. We do this by fermenting fiber.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
The big problem here is throughout the majority of human evolution, we were consuming 100 to 150 grams of dietary fiber a day. Now, the average person in the Western world consumes 10 to 15 grams of dietary fiber a day. But the average person on a standard American diet is only consuming 1 to 3 grams of fiber a day. Wow. So we're not getting the fuel to produce hydrogen.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And the bacteria that are breaking down fiber in this process and releasing H2 gas, they're like any living thing. If you stop feeding them, they die. And that is one of the reasons we're getting this dysbiosis of the microbiome. These hydrogen-producing bacteria are dying out. They're being replaced by methane-producing bacteria.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So actually when we do studies, we can look at a high percentage of middle-aged and older metabolic-impaired people. We give them a hydrogen breath test after lactulose, and they produce more methane than hydrogen, or no hydrogen at all. And this is critically important because we know... that methane is strongly correlated with basically every disease outcome. It's correlated with mortality.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So I'll be as brief as possible so you can focus on the good stuff. But as we were talking about earlier, I mean, up until this event in my life, I would research learn about something for a few months and then get bored and move on. And so I was kind of a generalist. I had an encyclopedia of knowledge on a million different things, but wasn't really close to an expert on anything.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And we also know that hydrogen is correlated with longevity. So a study in centenarians, so people over 100 in Okinawa, found that these centenarians had higher breath hydrogen than the average young person. Wow. So their lifestyle had carried it through. Which meant they had the healthy microbiome to produce the hydrogen gas. Yeah.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And as we know with a lot of the gut dysbiosis, some of the bacteria doesn't come back. Right. Right. So for a lot of people that have not lived a perfect lifestyle, which who has, you can maybe only get your hydrogen at the right dose exogenously through hydrogen water or hydrogen inhalation or gas. Yeah. Yeah.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Hydrogen water gets into the gut a lot better than inhalation. They elevate different tissues in different capacities. It's better for a lot of these metabolic conditions.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
an anti-inflammatory you know we can measure it's it's orp i've got an orp meter right here we can measure its oxidative reduction potential it's highly negative which is great um but explain that mechanism this is actually where it gets kind of interesting and makes hydrogen a lot more profound than just a standard anti-inflammatory or an antioxidant so hydrogen is in fact a weak antioxidant in vitro
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And, uh, Fast forward to when I was 29 and I was running a successful business in a completely different industry on an innovation I'd had there. But that business was giving me a lot of free time. I was on the road like a week out of the month. And when I was at home, I was working like an hour a day, two hours a day.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So outside of a living body in a test tube or a cell culture, which is why we can get a negative ORP from it. But how it's actually working as an antioxidant in vivo is similar to how exercise works. It's actually acutely an oxidative stress in the mitochondria. That's what's actually triggering Nrf2 reaction.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
you know, activation, which exactly, which we produce more glutathione, catalase, superoxide dismutase. So we're producing more of our endogenous antioxidants and it's only driving towards homeostasis. And this is actually critically important because there are a lot of deleterious effects from taking too high of antioxidants, right?
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
You can go into reductive stress, which is as harmful as being in oxidative stress. So hydrogen just drives towards redox homeostasis. It's getting this harmony back. Between the yin and yang are reductive molecules.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Exactly, and it's doing the same thing with inflammation. So it can actually acutely spike inflammation just like exercise. Exercise will release interleukin-6, which is one of the nastiest pro-inflammatory cytokines, but it's such a low amount from skeletal tissue that it's a myokine role. And hydrogen does the same thing, which drives this harmonious inflammatory response.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And a lot of people just think of inflammation as a bad word. It's only bad when it's not behaving how it's supposed to. Mm-hmm. Inflammation is critically important to our physiology. It's part of our healing. Exactly. Nothing in the body would heal without the inflammatory response. Exactly. It's part of our immune system to fight off viruses.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Actually, that was one of the big issues with COVID-19. A lot of people's bodies weren't recognizing it was a threat, so they didn't have sufficient inflammatory response at the beginning. And then once the virus started taking over, their body would panic, and they'd go into cytokine storm. Right.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Having this healthy, harmonious inflammatory response is incredibly important and hydrogen drives that. And it does that for a lot of other processes too, like autophagy. You know, it's all the rage and anti-aging with autophagy. And a lot of people think, oh, I want to always be activating autophagy. But no, you want to intermittently activate autophagy.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And in a lot of research, hydrogen has shown to actually activate autophagy. But in some important studies, it's shown to inhibit autophagy. like after heart failure and drowning resuscitation, when you absolutely don't want that to happen. So in a way, it's kind of, we'll explain hydrogen, kind of like a supervisor in our cell.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So I was basically training as if I was a professional athlete, even though I wasn't. I was training four to six hours a day five days a week, six days a week, and having an active recovery day once or twice a week. And this was like Muay Thai, Jiu-Jitsu? Yeah, various martial arts, CrossFit. I did some CrossFit competitions at the time, too. And I was in by far the best shape of my life, right?
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And we've talked about this before. So there's really cool research on hydrogen with other hormetic stresses, whether it be heat exposure, cold exposure, or exercise, that acutely hydrogen is actually increasing the stress response. But then after the stress finishes, it's driving back to homeostasis faster. Wow. So like with exercise, that's as if you worked out harder and recovered quicker.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Yeah. Because it's spiking the inflammation and oxidative stress higher and then dropping back down to homeostasis faster.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
unit like they won the lottery but i've seen it we we have a couple clinical trials using uh you know i can't wait for those yeah these h2 tabs um you know in bathing yeah right and anecdotally like uh as we talked about i i love martial arts i'm a lifetime martial artist and um a buddy of mine uh is a former ufc fighter and during one of his camps he he uh cracked his rip right like um
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And he was a, I gave him a ton of H2 tabs, right? And he was taking daily baths. And he was able to continue training every day and make his fight. Wow. Six weeks later when he cracked his rep. Wow. So really cool anecdotes like that.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Hydrogen is regulating inflammatory response, but it's actually increasing blood plasma flow. So this was an acute study, and I wish we'd recruited more people. I think it was only like 12 participants. And we were equivalent to Rice Protocol, but... in four very important markers, we had strong trends to be better after this single session than Rice Protocol.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
I think the professor told me if we'd recruited like three more people, it would have been significantly better than Rice Protocol in lowering inflammation, improving range of motion and decreasing the visual analog score for pain. And there was another I can't.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And... All of a sudden I got really sick and they never were able to figure out what happened, but it's most probable I had some sort of virus that caused an autoimmune reaction. So basically overnight I developed sudden onset narcolepsy. You know, if I sit down and wasn't engaged for a minute or two, I'd fall asleep. I was sleeping like 16 hours a day. I had crushing fatigue.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And, you know, we have a rat study that came out of the Stony Brook in New York for post-stroke recovery that found some synergy between hydrogen and minocycline, right, to improve the post-stroke recovery. And Sundaybrook actually has a clinical trial underway on post-stroke recovery. Wow. So there's a lot of cool research that's coming down the pipe here.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
As I mentioned, we've got over 20 human studies. I think we have five more that are either finishing up peer review or in press that are about to publish and 15, 20 more that are in the planning stages underway. So the research isn't stopping. And actually because of my devotion to research,
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
advancing the research on hydrogen therapy, Dr. LeBaron from the Molecular Hydrogen Institute just invited me, and I accepted, to be a... Smartest guy I've ever spoken to about hydrogen. That guy will spin your beanie. If we're going to go into, say, the biochemistry of hydrogen, he is the top in the world. He understands the biochemistry of what hydrogen does in the body better than anyone.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
where the only thing I'd say that I have an advantage of him on is I have a better memory and I've read more papers than him. So it's not a contest. Sorry, Tyler. No, no, no. But I mean, he's exponentially more knowledgeable than me in the biochemistry, like exponentially. Right.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So I'm taking a sliver here, but he's invited me to be the first chairman of the hydrogen research committee under the MHI. So it's a volunteer position. And basically what I'll be doing is I'll be working with the MHI and working with the public in industry. So Dr. LeBaron has hired another PhD, Dr. Grace Russell from the UK, who's published a lot of research on hydrogen.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And I know her personally. She's going to be helping research teams fill in NIH grants. to get more funding for hydrogen research in the United States. And I'm going to be working with the public in industry to get more funding, to fund this research, in addition to supplement the NIH grants, and also to do outreach with the universities. Because that was one of the first things I did.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
I emailed, like I said, every first and corresponding author on every... study that I could find. So we're going to be doing that and saying, hey, this is where the evidence is. We can help these NIH grants. We can connect with industry to get further funding. And then at the end of the day, once we get partners that have all agreed,
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Dr. LeBaron and I are going to review the protocols to make sure that the targets make sense, the methodology makes sense, the dosing makes sense.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And we've reversed metabolic syndrome, you know, in a double-blind placebo-controlled trial with 60 people over six months. By the way, I'm going to link all these studies into the show notes below. I think it was 21 of 23 measured outcomes. We had a significant clinical and statistically significant impact.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
two tabs to drinking water. It was three H2 tabs a day and 12 ounces of water in these people, middle-aged and older with metabolic impairment. So that would cost you less than three bucks. Yeah. So we reversed metabolic syndrome. We've shown weight loss in weight loss or improved body comp in, I think it's six studies now. Now, how would the gas improve body composition or weight loss?
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
He had crushing fatigue. I had also central nervous system fatigue. So basically I Went from being able to do like 20 bar muscle-ups unbroken to I couldn't do a chest apart or a 54 inch plyometric box jump to I couldn't get airtime I couldn't jump an inch off the ground with both feet Wow And I couldn't sprint, do anything that was explosive and reactive.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So it could improve muscle mass by improving exercise recovery and energy output and everything like that. And we're actually finding some cool research. Some of this is not published yet, but I'm an author on some of it. I'll touch on it briefly, but we're regulating appetite. GLP-1. GLP-1. So we do have a study in mice under peer review right now that we regulated GLP-1. We had an effect.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And we have a clinical study, 12-week, I think it was N of 40, 40 participant double-blind placebo control. in obese, metabolically impaired people where we increased GLP-1, right? Wow. In addition, we regulated ghrelin already in a clinical trial on overweight people. And ghrelin is often called in pop culture like the hunger hormone. But it actually has a lot of other roles.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
It regulates our insulin response, glucose, homeostasis. It has a lot of neuroprotective effects. And what is poorly understood by the general population and even some physicians is that we actually want a peak and valley of ghrelin. So we want ghrelin to be very high when we're... on an empty stomach and crashed to nothing. Right. And in obese people, it becomes impaired.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So there's no peaks and valleys. It's just kind of in the middle all the time, which is why they're always snacking. They're never really hungry, but hungry. Yeah. And hungry, but also they're never really as hungry as a healthy person. They're just kind of hungry and snacky all the time. So we actually show to restore that, uh,
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Fasting Peak in Valley, and we're working on some more research in there. And we had another study where we improved and modulated the brain chemistry involved in satiety. So there's some interesting stuff there. We're actually planning several other large studies you know, clinical trials on metabolic outcomes with hydrogen. Some of them are currently enrolling.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Others are in the planning stages set to kick off in March. We're doing two of them in Serbia, one in Russia and one in Australia.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
But my slower movements, like my deadlift, my squat, my bench press, were completely unaffected. My strength was normal. Wow. Right? In addition, I had very high markers of inflammation. C-reactive protein. My C-reactive proteins were about 100 times abnormal. Wow. They were, you know, 34 milligrams a liter. Wow. At its peak.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
That's very important because there are certain bacteria that can come back within a few days or a week. There's others that might take months or years. And there's bacteria strains that we've identified by looking at like tribal peoples that we've discovered in the Amazon or South Asia where could be generational. They might never come back once we've lost them.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Now, in that same study where we regulated ghrelin, we reduced calprotectin, so a marker of inflammation in the stomach, and we improved a couple of short-chain fatty acids, propionic and butyric acid. Oh, wow.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
There's some definite... gut links and actually hydrogen water uniquely gets into the gut a lot better than inhalation obviously is going to your lungs. So that's why I was mentioning hydrogen water and hydrogen inhalation have different pharmacokinetics. They elevate different tissues in different capacities. So hydrogen water interacts with the gut better.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
It gets to the liver at a higher concentration and some of the internal organs, which is why it's perhaps better for a lot of these metabolic conditions. Whereas inhalation, it's getting obviously to your lungs better. It's getting to your muscles at a higher amount than drinking hydrogen water. So a lot of musculoskeletal issues, maybe inhalation will be better.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
For athletes, maybe you want to do both. And it's getting both are getting to the brain inhalation a little bit higher than hydrogen water. But hydrogen water also has the gut brain connection. It's improving your gut. So it's improving your brain. So I think the future we're going to be doing several modalities of hydrogen therapy. People are going to be doing.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
drinking high concentration hydrogen water, doing inhalation in a proper and safe way, bathing in hydrogen water. You know, there's hydrogen saline, like IVs, right, for purposes in the hospital.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So our studies range from one to, well, five tablets a day, but most of them one to three tablets a day at various volumes of water. I'm taking like five to eight. I take five personally, but I've got a lot of damage. Yeah, so first thing on an empty stomach is important. So the perfect volume of water is different for every person because it's the volume that you can chug, drink rapidly.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Right, at a room temperature. So because hydrogen is this stress, like H2 is this stress like exercise. You don't want to be sipping on it all day long. Right. That would be like you want to get the dosage.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Exactly. I do a liter, right? But most people can't chug a liter. So most of our research on athletes uses half a liter or 16.8 ounces. Our research on metabolic...
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And it's really important. You want to drink it on an empty stomach, right? So a lot of companies in hydrogen water don't actually talk about this because they don't understand it very well. But one, say you are producing a bit of hydrogen from consuming fiber. You don't want to be competing with that, right? You want that separately.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
But two, one of my patents involves I've turned hydrogen water and various fibers into dense foams and gels, right? It stabilizes. So if you eat it at a time where you've just had some fiber, you might not be getting rapid uptake into your system, which can affect the therapeutic value. So what we're learning right now in the hydrogen research We haven't found a plateau yet, right?
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
For most indications. So some indications we need vastly higher amounts of hydrogen that then we can reasonably. Reasonably intense exercise, severe metabolic syndrome, liver health. For instance, liver health, we need 10 times more exercise to start seeing an effect. So dose and concentration is critically important.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
But for the average person that's listening to this podcast, it says I'm sold one to three times a day, three times a day, three times a day, the most water that you can comfortably chug down in one to three gulps, you know, within 15 to 30 seconds and on an empty stomach. So sometimes I like is in the morning. or right before you exercise. Yeah, you know, that's what I do.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Or I do middle, middle of the afternoon or right before dinner, like you can eat 510 minutes after you drink the hydrogen water, just don't drink it after you eat.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Yeah, I mean, usually you might spike to, yeah, one to three when you're sick, when you have a cold or the flu or something. Right. Most healthy people are below 0.5. Right. Right. Like if you're metabolically healthy. You know, if you have chronic inflammation, you start trending up. But for a 29-year-old in the shape I was in, I should have been below 0.5, below 0.3.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
A hundred percent. And actually there's a systematic review and meta-analysis showing an anti-fatigue effect with hydrogen water. And we have a couple of really cool studies that I know I briefly told you about that are in press right now on the H2 tabs, right? Showing remarkable benefits. So in the first, and they were in completely different study populations.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So the first one was a shorter term study. I think it was four weeks. It was in Olympic athletes and it was done in Russia. And they were taking two tablets in 16.8 ounces or 500 milliliters a day, you know, before and after training. And we improved body composition in these Olympic athletes, which was incredible. But we also improved their peak torque on leg extension at the end of the trial.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And more significantly after they'd exercised and warmed up, showing the anti-fatigue effect. Wow, so they took it during exercise. Right before and right after. Right before and right after. And we have another trial in the opposite study population. This was a 50 plus group.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And I was actually just, I was one of the authors on both of these, but I was just in Milan, Italy at Aspen at a conference presenting this study, you know, with the corresponding author. And so these 50-plus people who had no adult experience with exercise, they were very out of shape, so much so that they were starting doctor-guided exercise protocols to try and turn their lives around.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Yeah, there's a huge deconditioned population right now. Exactly. And this was, off memory, I think it was six weeks, six or eight weeks, I can't quite remember. But it was, again, double-blind, placebo-controlled. And in the placebo group, we actually saw... some very concerning things. They were borderline rhabdomyolysis. So the stress from the exercise, um, dysregulated their cortisol response.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
It increased, uh, um, myoglobin by 11, a hundred percent, right? So 11 times, um, it increased creatine kinase by like seven times, 700%. They had serious. That's where they get the kidney issues with rhabdo. Exactly. Oh, and with the hydrogen group, and we actually saw this too in the Olympians, it didn't raise the creatine kinase at all, no significant rise.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So we had no significant rise in creatine kinase or myoglobin. We regulated the cortisol.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
response we improved dhea and free testosterone wow and we improved sleep outcomes specifically in females so we're actually seeing a potential gender response it's gonna love you man there's a few studies now both in press and one published where we had stronger results in females and males yeah so it could be mediated by estrogen we're still trying to figure this out yeah but
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Because all machines start breaking down over time, but the tablets are getting this high dose every time. Unless you have a lab to test the machine, you don't know when it starts to deteriorate.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
We actually have a few studies underway that are separating gender to look deeper into these gender-based responses. And we're starting, I've just signed off on the protocol, we're starting the very first responder study on hydrogen. Looking at people's endogenous breath hydrogen production over some time to establish the difference in effect of people with
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
low breath hydrogen versus high breath hydrogen.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
I think just constantly the pursuit to improve, right? Not perfection. Right. It's just growing and learning. And I think that that a philosophy behind maintaining is accepting that you're going to respond to things after it's broken. That's what it implies. So the only way we can stay satisfied is by always trying to move forward. So my philosophy in life is always forward, right?
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
You know, and forward in as many ways as you can, you know, trying to improve your health, trying to improve your purpose, your business, your family life, right? Everything, just always be trying to make small improvements. Most people want to say with money, go to bed poor and wake up rich without having to do any work. And, you know, it's an age old saying, but Rome wasn't built in a day.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And the only way we can continue moving forward and achieve what we dream to achieve is by taking one step at a time. That's awesome. One small improvement. Yeah, one small improvement.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Yeah. Yeah. Yeah. And my roommate got really sick at the time, too, and it hit him different. He actually had to go to the hospital a couple of times with pneumonia. Right. And this was a guy who was, you know, top three and triathlons and Spartan races. So, again, he was a super fit, healthy 29 year old that got taken out by by whatever hit us.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
It's just he didn't get the autoimmune response like I did.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
But this lasted a couple of months. And when the dust settled. I was left with polyarthritis. So I developed osteoarthritis in 11 joints. The worst of which is my left shoulder, which this is as high as it goes now. It's bone on bone. But also my hip was quite bad. My hands and, you know, basically anywhere I'd had an injury in sports throughout my long life of contact and combat sports.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
I was told I had to quit working out, right? Period. You cannot exercise more. You can't lift weights. Just walk, right? Maybe... do like some swimming just like with, you know, breaststroke or something that doesn't need the shoulder. And they put me on 1,000 milligrams of naproxen a day. So think like super Aleve. Like Aleve is naproxen, but you might get 200 milligrams.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So I was on five times that dose. And I was taking cortisone injections. And I just knew that none of this was how I wanted the rest of my life to go. And it wasn't a long-term solution. It was going to lead to long-term side effects. So the time I'd spent exercising, I just dove into PubMed.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And I just started reading any study I could find on regulating inflammatory response and any sort of therapeutic. Started a ton of different biohacks from going to cryo saunas and normal saunas. Just trying to get this out of you, whatever it was. Just trying to get it out. And at the time, I found some research on hydrogen water. And the industry was very nascent at the time.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
There was only 40, 50 studies. But I found a couple of clinical trials. And I bought a machine for like $5,000. This water and hydrogen gas. Purportedly.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
okay so i went on my merry way and uh didn't know if what if anything was working because i was still taking the naproxen and the cortisone injections and um trying to get back into exercise and eight or nine months later i fainted a few times in the gym so i developed multiple ulcers from the naproxen and i had to abruptly stop right um so
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
basically as i stopped the naproxen i hadn't had a cortisone shot in a while all my joints froze within a few days wow so i realized that nothing i was doing was really helping like going to the sauna and the cryo it would help for a few hours or the rest of the day but then i'd wake up right rough again and you just stiff as a board exactly right i couldn't put on uh socks without sitting down or lying down i couldn't put on jackets and and some shirts like it was rough and uh
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
I went back to PubMed and I just started reading more and more. And in this nine month period, I found some new research on hydrogen water. And at first it pissed me off because I had this $5,000 paperweight that wasn't helping. But then it just dawned on me. I took the salesman's word for it that this made hydrogen water. how do I know there's hydrogen gas in here and what dose is needed?
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So I started buying the full studies to read the material and methods, and I found that not a single one of them at the time were using a machine like what I'd bought. They were making the hydrogen water in labs in various ways, like bubbling gas or using magnesium under pressure.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So then I found a reagent to test for hydrogen gas and water, and I ordered it, and the first test it detected no hydrogen. I had to over triple the input to reduce a single drop, putting it at... Is that the methylene blue test? Yeah, putting it at like 0.03 parts per million, which is well below the lowest ever observed Any kind of therapeutic dose.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Any type of physiological effect on the body, like 1 1 30th of the lowest observed minimum threshold to do anything. So that gave me a bit of hope. And I went about trying to source magnesium, which was going to be the easiest way for me to do it.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And first I sourced some rods, and then I had some concerns that with magnesium rods, I don't know how much magnesium I'm getting, and I didn't want to get hypermagnesia. And so then I was sort of thinking I need a powder so I can control the dose. Quickly realized it's very hard to get elemental magnesium powder. Like in the United States, it's... controlled by the State Department and DOD.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
You have to go through background checks and everything. So I sourced some from Eastern Europe and some from China at first, and they arrived saying, like, silver paint coloring powder. I'm like, okay, this is a little bit sketchy, but I tried anyways. I figured the powder floats, so I wasn't able to make the hydrogen water, and I'm going to need to compress this.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So that's where the tablet idea came.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Yeah, so basically the elemental magnesium and the organic acids we're using are reacting with the water, and it's breaking that bond between the H2 and the oxygen, right? And that's what creates these small nanobubbles that you see in the water so you can drink down the hydrogen water. Now...
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Basically, the magnesium in a couple of complex reactions goes from the elemental magnesium to just free magnesium ions, Mg2+, which is exactly what our body needs. So it doubles as a highly bioavailable magnesium supplement.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So many people sleep overnight by adding magnesium. And you likely know there's big bioavailability concerns with a lot of the magnesium supplements on the market. Someone might go buy a magnesium oxide that's on average 4% or 5% bioavailable. So we're delivering it in the exact form your body needs. Your stomach doesn't have to liberate it off of
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
another compound, it just freely goes into your system. So it's completely bioavailable because of the way we're delivering it. So yeah, when I started developing these tablets, I quickly started feeling better.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Were you bathing them? Were you both? I was drinking. So I was drinking several liters a day. And I was getting, at first, to about three parts per million, sealing them under pressure. And my joints loosened. I felt better. I'm like, wow, there's something here. But then I had a bit of a sober second thought. I didn't want to win a Darwin Award.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
You know, like blow yourself up, blow myself up in my kitchen with hydrogen gas.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Fifty eight hundred degrees Fahrenheit. Right. It's the white and fireworks. Right. Which is why it's so, so tightly controlled. And I had to go through background checks and everything like that. But also too, like I wanted to test for heavy metals and contaminants and is there any dangerous side reaction that's happening?
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Like I understood enough about the basic chemistry, but I'm not a chemist, right? So I found my founding partner, you know, Dr. Richard Holland, he's a PhD in organic chemistry. He works in the pharmaceutical industry. So he designed small molecules for different therapeutic topic, targets. And I found him, um, he was doing consulting work, offering it.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And I told him about my project and he said, this is the worst pseudoscience I've ever heard in my life. Not what you wanted to hear. Yeah. Well, he gave me a list of reasons why it wouldn't work. Why you like hydrogen has no role in the body. And even if it did, you should inhale it and not drink it because of the low saturation point. And, If you'd like, we can get into that later.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
The pharmacokinetics of inhalation and water are actually completely different. So they hit different organs in different ways. But because I'd read every study to date on hydrogen as a therapeutic, like at that time, I was able to rebut all of his responses with peer reviewed evidence. And he came back to me and said, like, I'm actually in shock. Right.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
I still don't really believe it, but there's enough that I can help you out. Sure. Right. So he starts tweaking my formula. I'm sending him a new publication every day just to pique his interest because I'm really excited about the project. And he calls me for lunch. And serendipitously, I sent him this clinical trial on a certain disease state, and it was a decent size.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
And it was using a high concentration at the time, about five parts per million over a liter a day. And it found pretty good results in this group, in this population. And I was not aware, but his current job was developing small molecules for this exact study. Wow. And he said, you know, with the other studies you've sent, I'm not a subject matter expert. Right.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
So I just have to trust the findings, look at the methodology and trust the researchers. But with this, I am. And unless this is fraud, this works and it works better than the molecules I'm developing. Right. Are you interested in commercializing this? Right. So I thought long and hard about it. Um, I had no expertise in this area.
The Ultimate Human with Gary Brecka
150. Alex Tarnava: Unlocking Longevity with Hydrogen Water - Anti-Aging, Increased Energy & Reducing Inflammation
Um, and I was just doing this as a do it yourself project for my own health, but I figured why not? What do I have to lose? I can learn as I go, let's do this. Right. So I proceeded forward and, uh, It only took a few weeks to refine. There wasn't much changes to my formulation to get to work in a mortar and pestle. But then the hard work started.