303 | James P. Allison on Fighting Cancer with the Immune System

2876.854 - 2902.842 James P. Allison

Drugs in the form of, right now, one of the popular things are antibodies. These are just proteins that we can make that are very specific. I mean, that's what we did with CTLA-4 in the 90s. There was this molecule, and it was funny. It looked like a molecule that was the gas pedal of T cells, but this molecule called CTLA-4, and we showed that it was actually not a gas pedal, it was a brake.