291 | Venki Ramakrishnan on the Biology of Death and Aging

3407.211 - 3434.31 Venki Ramakrishnan

So all of these proteins that accumulate that are defective or entire organelles that are defective are taken to the lysosome and recycled, basically degraded and recycled. But that process called autophagy can also decline with age. And then cells themselves can decline. So I pointed out that when cells are stressed, when they sense damage, they go into a state called senescence.