BackTable Urology
Ep. 210 Personalizing ADT Across the Prostate Cancer Spectrum with Dr. Rana McKay
Tue, 21 Jan 2025
What is the role of androgen deprivation therapy (ADT) in prostate cancer treatment? In this episode of the BackTable Urology Podcast, Dr. Rana McKay, a medical oncologist from UC San Diego, joins host Dr. Aditya Bagrodia to discuss the administration of ADT and other management strategies for prostate cancer. --- This podcast is supported by: Photocure https://www.photocure.com/ --- SYNPOSIS The doctors offer a historical perspective into the evolution of ADT over time and discuss the variety of different ADT treatment options available. They compare management strategies for localized and metastatic prostate cancer and discuss how to align therapy with patient goals, focusing on the side effects. The conversation also explores the impact of prostate-specific membrane antigen (PSMA) PET imaging on management and the future directions of hormonal therapies in urologic oncology. --- TIMESTAMPS 00:00 - Introduction 05:25 - ADT Options 10:36 - Choosing an Agent and Managing Side Effects 26:42 - Continuous Versus Intermittent Therapy 30:30 - Closing Remarks --- RESOURCES Photocure https://www.photocure.com/
Full Episode
We know that TURBT procedure is critical in the care of patients with non-muscle invasive bladder cancer. With data that shows that CIS was missed by TURBT in more than 45% of radical cystectomy cases and 86% of residual tumors have been found at the original resection site, it's clear that enhanced visualization could be a significant benefit during TURBT's.
Further, with only 23% of patients coming back for re-resection, it's all the more important to do a complete TURBT right from the start.
everybody does it different, every doc doesn't different, there isn't sort of like a system. So I think like kind of being a little bit more systematic about, you know, these are the options that you have.
And these are the side effects, you know, at our institution, a DTF kind of we piloted together kind of like an ADT order set, you know, like when you're going to start ADT, these are the things to think of, these are the labs to think of, this is the imaging, here's the teaching. And I think that that really kind of takes out a lot of bias from the process.
So I think standardization is important and also kind of seeing what the goals are for the patient and aligning with them is really key.
This is Aditya Bagrodia as your host this week. And I'm very excited to introduce our guest today, Raina McKay, who's one of my partners here at UC San Diego. Welcome back to the show, Raina. How are you doing today?
I'm doing great. Thanks for having me.
Oh, it's a pleasure, Raina. I literally think every time I interact with you, I get inspired and I get smarter. And, you know, what you're able to do for our team and for the GU community is amazing. And I've got to take this opportunity to throw a little plug in. Raina is on the ballot for the nominating committee for ASCO elections this year.
There's literally I don't think anybody who's out there currently that's contributed so much to our field and oncology in general. So if you're a member, get out there and vote for Raina. She's amazing. You don't need me to tell you that. All right, Raina. So this is actually an episode that is kind of backed by request and popular demand.
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