Ep. 186 Blue Light Cystoscopy: Improving Bladder Cancer Detection with Dr. Suzanne Merrill
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This week on the Backtable podcast.
The data really over time has shown us that blue light is a technology that should be offered to our patients, that it has good enough evidence behind it, that it can impact our patients course of disease and outcome. Even back in 2013, there was a meta-analysis of nine studies, which ultimately showed that detection of TA and T1 lesions may be up to 25% greater, okay, with blue light cystoscopy and use of CISFU. than compared to white light. And overall, this translated looking at really the raw data from this meta-analysis that the rate of recurrence with use of blue light can be reduced by about 11%, and it can certainly prolong the time to recurrence by about seven-ish months.
Welcome to the Backtable podcast, your source for all things urology. You can find all previous episodes of our podcasts on Apple Podcasts, Spotify, and at backtable.com. We all know that TURBT procedure is critical in the care of patients with non-muscle invasive bladder cancer. Unfortunately, there's data that shows that carcinoma in situ, or CIS, was missed on TURBT more than 45% of the time on subsequent radical cystectomy cases. And 86% of residual tumors have been found at the original resection site. With this, it's clear that enhanced visualization is of utmost importance and will be a significant benefit during TURBT. Furthermore, patient compliance can often be an issue, with only 23% of patients coming back for re-resection. It's therefore all the more important to ensure a complete TURBT The first time, right from the start. Listen to this podcast interview with Dr. Suzanne Merrow, who discusses the benefits of blue light cystoscopy to enhance visualization and ensure a high quality TURBT.
I'm your host today, Dr. Suzette Sutherland, and I'm super excited to have Dr. Suzanne Merrill here today to talk to us about diagnostic aspects of bladder cancer and how to enhance that, specifically with a newer type of technology called blue light cystoscopy. Thanks for being here with us today, Dr. Merrill. It's my pleasure. Thanks for having me, Suzette. Yeah, let me tell you a little bit about Dr. Suzanne Merrill. She is trained at Duke University for her urology residency and then did a GU oncology fellowship at Mayo Clinic in 2015. She's now 10 years out of fellowship, so she has a lot of experience under her belt. She started on faculty at Penn State Hershey Medical Center. where she was program director there too for the urology residents.
And now since about a few years, since 2021, she's in Colorado at Colorado Urology, which is under a bigger umbrella of United Urology and specializing in GU oncology and also considered a regional bladder cancer specialist. So she really knows what she's talking about here today. And I'm so happy that she's here to share that with us today. Well, thank you. So let's just get started. Like, first of all, just a couple of, you know, good fun facts, I suppose, not so fun. But, you know, we know bladder cancer, it seems like it's getting even more common today than it was even when I was training. It's quite common, more so in men than women. Tell us the statistics around the epidemiology today.
Yeah, of course. It's a lot more surprising when we're talking to our patients about how common bladder cancer is. So in 2024, it ranks as the fourth most common cancer in men and the sixth most common cancer in the U.S. for both men and women. And so superficial bladder cancer actually comprises of greater than 60% of all our new diagnoses that go on. And when people get superficial bladder cancer, the main concern is that there is a high risk of recurrence. And that recurrence in just year one can be as high as 60 percent and obviously escalates going forward in time. So this discussion we're going to have today about diagnosing it, getting the right stage and grade done, And fully taking care of it when we go in for that TURBT is absolutely critical for both our patients and getting them on the right track for treatment.
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